Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chao-Jiang Gu"'
Autor:
Boe-Hyun Kim, Eran Hadas, Jennifer Kelschenbach, Wei Chao, Chao-Jiang Gu, Mary Jane Potash, David J. Volsky
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract HIV enters the brain within days of infection causing neurocognitive impairment (NCI) in up to half of infected people despite suppressive antiretroviral therapy. The virus is believed to enter the brain in infected monocytes through chemota
Externí odkaz:
https://doaj.org/article/bc0bc38fa5a3440cac15f2ef92457fdc
Autor:
Jennifer Kelschenbach, Hongxia He, Boe-Hyun Kim, Alejandra Borjabad, Chao-Jiang Gu, Wei Chao, Meilan Do, Leroy R. Sharer, Hong Zhang, Ottavio Arancio, Mary Jane Potash, David J. Volsky
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT HIV causes neurodegeneration and dementia in AIDS patients, but its function in milder cognitive impairments in virologically suppressed patients on antiretroviral therapy is unknown. Such patients are immunocompetent, have low peripheral an
Externí odkaz:
https://doaj.org/article/647ff4c2424c40439623f7e83ef035e1
Autor:
Chao-Jiang Gu, Alejandra Borjabad, Eran Hadas, Jennifer Kelschenbach, Boe-Hyun Kim, Wei Chao, Ottavio Arancio, Jin Suh, Bruce Polsky, JoEllyn McMillan, Benson Edagwa, Howard E Gendelman, Mary Jane Potash, David J Volsky
Publikováno v:
PLoS Pathogens, Vol 14, Iss 6, p e1007061 (2018)
Suppression of HIV replication by antiretroviral therapy (ART) or host immunity can prevent AIDS but not other HIV-associated conditions including neurocognitive impairment (HIV-NCI). Pathogenesis in HIV-suppressed individuals has been attributed to
Externí odkaz:
https://doaj.org/article/3593da4864114c1e82e78c8b2f270cc6
Autor:
Hui Li, Tong-Cun Zhang, Li Hanhan, Li Wang, Jia Peng Li, Yuan Xiang, Xiao-Yu Zhang, Yuan-Yuan Duan, Chang Chang Fan, Zhang Huimin, You Huang, Qian Chen, Xing-Hua Liao, Chao Jiang Gu, Yu-Yang Wang
Publikováno v:
Oncology Research
Abnormal cell proliferation caused by abnormal transcription regulation mechanism seems to be one of the reasons for the progression of breast cancer and also the pathological basis. MicroRNA-142-5p (miR-142-5p) is a low-expressed miRNA in breast can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca911d34565a92eb7c0f28181d3ca19
https://doi.org/10.3727/096504021x16274672547967
https://doi.org/10.3727/096504021x16274672547967
Autor:
Hui Li, Li Hanhan, Tong-Cun Zhang, Jia-Peng Li, Feng Huang, Xing-Hua Liao, Zhang Huimin, Liu Meijun, Zhou-Tong Dai, Chao Jiang Gu, Yuan Xiang
Publikováno v:
Journal of Cellular Biochemistry. 121:3392-3405
Although many methods and new therapeutic drugs have been developed, the overall survival rate and long-term survival rate of patients with gastric cancer (GC) are still not satisfactory. In this study, we investigated the effects of microRNA miR-133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ab3251b83d1bf256a4d2caced2d2d0
https://doi.org/10.1002/jcb.29613
https://doi.org/10.1002/jcb.29613
Autor:
Kun Chen, Han Han Li, Jun Wang, Zhang Zijian, Zhang Huimin, Zhou Tong Dai, Tong-Cun Zhang, Yuan Xiang, Leyuan Bao, Chao Jiang Gu, Feng Huang, Xing-Hua Liao, Hui Li, Jia Peng Li, Wei Guo
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-13 (2020)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
BackgroundFoxp3+CD4+regulatory T cells (Treg) constitutes a key event in autoimmune diseases. STAT5b is the critical link between the IL-2/15 and FOXP3, the master regulator of Treg cells.MethodsThe CD3+T cell and Foxp3+CD4+regulatory T cells were ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3897d13d4830ae466341cd5bada108e
https://doi.org/10.1186/s12964-020-00574-1
https://doi.org/10.1186/s12964-020-00574-1
Autor:
Xing-Hua Liao, Chao-Jiang Gu, Tong-Cun Zhang, Hui Li, Li Hanhan, Zi-Tan Peng, Zhang Huimin, Jia-Peng Li, Yuan Xiang, Fan Lijuan, Li Wang, Xiao-Yu Zhang
Publikováno v:
International Journal of Medical Sciences
Endothelial cell proliferation disorder caused by vascular injury seems to be one of the causes of atherosclerosis, which is the pathological basis of coronary heart disease. The role of STAT3 in the regulation of microRNAs and endothelial dysfunctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa05f56596b03d3c4fa5f858ca8c7de1
https://pubmed.ncbi.nlm.nih.gov/33456354
https://pubmed.ncbi.nlm.nih.gov/33456354
Autor:
Xing-Hua Liao, Chao-Jiang Gu, Tong-Cun Zhang, Ao Yao, Hui Li, Qin Huan, Cheng-Xi Yu, Yuan Xiang, Jia-Peng Li, Peng Hu, Wei Guo
Publikováno v:
Oncotarget
Signal transducer and activator of transcription 3 (Stat3) and Myocardin regulate cardiomyocyte differentiation, proliferation, and apoptosis. We report a novel aspect of the cellular function of Myocardin and Stat3 in the regulation of cardiomyocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3c8a5f56a8a267393f5a1700127023
https://doi.org/10.18632/oncotarget.20450
https://doi.org/10.18632/oncotarget.20450
Autor:
Chao-Jiang Gu, Jia-Peng Li, Qin Huan, Peng Hu, Tong-Cun Zhang, Xing-Hua Liao, Wei Guo, Hui Li, Yuan Xiang, Ao Yao, Cheng-Xi Yu
Publikováno v:
Experimental Cell Research. 357:135-144
Epithelial-mesenchymal transition (EMT) plays an important role in breast cancer cell metastasis. Both (megakaryoblastic leukemia)/myocardin-like 1 (MKL-1) and Signal transducer and activator of transcription 3 (STAT3) have been implicated in the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55f6ac9a54a1905f4106406b20dacec
https://doi.org/10.1016/j.yexcr.2017.05.007
https://doi.org/10.1016/j.yexcr.2017.05.007
Autor:
Hong Zhang, Hongxia He, Jennifer Kelschenbach, Boe-Hyun Kim, Wei Chao, Mary Jane Potash, David J. Volsky, Meilan Do, Alejandra Borjabad, Leroy R. Sharer, Ottavio Arancio, Chao-Jiang Gu
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
mBio, Vol 10, Iss 4, p e00591-19 (2019)
mBio
mBio, Vol 10, Iss 4, p e00591-19 (2019)
mBio
HIV neuropathogenesis has been attributed in large measure to neurotoxicity of viral proteins and inflammatory factors produced by infected monocytic cells in the brain. We show here that HIV expression in mouse brain causes lasting memory impairment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68cf7f0f346a5e9c13a705bfd7641deb
https://journals.asm.org/doi/10.1128/mBio.00591-19
https://journals.asm.org/doi/10.1128/mBio.00591-19