Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Chao-Jian Guan"'
Autor:
Yi-Tong Li, Cong Yi, Chen-Chen Chen, Huan Lan, Man Pan, Shao-Jin Zhang, Yi-Chao Huang, Chao-Jian Guan, Yi-Ming Li, Li Yu, Lei Liu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Acetylation of Atg3 regulates lipidation of Atg8 and therefore autophagy, but the molecular mechanisms remain unclear. Here, Liet al. semi-synthesize diacetylated Atg3, allowing them to show that acetylated Atg3 enhances Atg8 lipidation by promoting
Externí odkaz:
https://doaj.org/article/996b13abaf3f4b26a3749dc108a6dce0
Publikováno v:
Tetrahedron Letters. 58:1677-1680
The use of pre-prepared diaminodiacids has been established as an effective approach for the chemical synthesis of peptide disulfide bond mimics. A technical problem often encountered in the implementation of the diaminodiacids strategy is the use of
Autor:
Lei Liu, Chao-Jian Guan, Yi-Chao Huang, Huan Lan, Yi-Tong Li, Li Yu, Cong Yi, Man Pan, Yi-Ming Li, Chen-Chen Chen, Shaojin Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Nature Communications
Nature Communications
Acetylation of Atg3 regulates the lipidation of the protein Atg8 in autophagy. The molecular mechanism behind this important biochemical event remains to be elucidated. We describe the first semi-synthesis of homogeneous K19/K48-diacetylated Atg3 thr
Publikováno v:
RSC Advances. 6:47926-47930
The analogue of ubiquitin-based probe ubiquitin–7-amido-4-methylcoumarin (Ub–AMC) was efficiently synthesized through a methyl thioglycolate (MTG) assisted one-pot ligation–desulfurization protocol. To obtain peptide segments with higher yield,
Publikováno v:
Organic & Biomolecular Chemistry. 13:1500-1506
In this work, we describe an accelerated solid-phase synthetic protocol for ordinary or difficult peptides involving air-bath heating and amide protection. For the Hmsb-based backbone amide protection, an optimized acyl shift condition using 1,4-diox
Publikováno v:
Chemical Communications. 51:13189-13192
Rapid and catalyst-free hydrazone ligation reaction between ortho-halobenzaldehyde derivatives and peptide/protein hydrazides was observed at neutral pH and room temperature. 2-Chlorobenzaldehyde exhibited the fastest reaction and highest conversion
Autor:
Yang Xu1, Tao Wang2, Chao-Jian Guan2, Yi-Ming Li2, Lei Liu3, Jing Shi1 shijing@ustc.edu.cn, Bierer, Donald4 donald.bierer1@bayer.com
Publikováno v:
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Apr2017, Vol. 58 Issue 17, p1677-1680. 4p.
Publikováno v:
RSC Advances; 2016, Vol. 6 Issue 53, p47926-47930, 5p
Publikováno v:
Chemical Communications; 8/28/2015, Vol. 51 Issue 67, p13151-13157, 7p
Autor:
Xu, Yang, Xu, Ling, Xia, Yuan, Guan, Chao-Jian, Guo, Qing-Xiang, Fu, Yao, Wang, Chen, Li, Yi-Ming
Publikováno v:
Chemical Communications; 8/28/2015, Vol. 51 Issue 67, p13189-13192, 4p