Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chao-Hen Kuo"'
Publikováno v:
Toxicology. 22:149-160
The effect of trans -stilbene oxide (TSO) on organ function and morphology and on drug-metabolizing enzymes was determined in male Sprague-Dawley rats. TSO (300 or 600 mg/kg) was administered i.p., once daily for 5 consecutive days. At a dose of 300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d2b8081452f8ba7b264853597b2f20
https://doi.org/10.1016/0300-483x(81)90114-1
https://doi.org/10.1016/0300-483x(81)90114-1
Publikováno v:
Experimental Biology and Medicine. 174:165-171
Piperonyl butoxide has been shown to reduce accumulation of cephaloridine in rabbit renal cortex; however, the mechanism responsible for this effect remains unclear. Cepha- loridine is a zwitterion and its accumulation in renal cortex has been sugges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25261e15410f673e7b1fca35cf95b9e5
https://doi.org/10.3181/00379727-174-41720
https://doi.org/10.3181/00379727-174-41720
Publikováno v:
Toxicology and Applied Pharmacology. 64:244-254
Cephaloridine causes necrosis of renal proximal tubules in humans and laboratory animals. This antibiotic nephrotoxicity in rats has been shown to be reduced by mixed-function oxidase (MFO) inhibitors such as piperonyl butoxide and cobaltous chloride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab629c2cf36021aefc01e5f3c0340b3a
https://doi.org/10.1016/0041-008x(82)90221-6
https://doi.org/10.1016/0041-008x(82)90221-6
Publikováno v:
Toxicology and Applied Pharmacology. 67:78-88
Cephaloridine produces renal cortical injury, but the precise mechanism responsible for this nephrotoxicity remains unclear. Recently cephaloridine has been shown to deplete reduced glutathione (GSH) concentration selectively in renal cortex. Cephalo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abfbac0079477a098edbea5954034d8
https://doi.org/10.1016/0041-008x(83)90246-6
https://doi.org/10.1016/0041-008x(83)90246-6
Autor:
Jerry B. Hook, Chao-Hen Kuo
Publikováno v:
Life Sciences. 27:2433-2438
Postnatal development of renal and hepatic drug-metabolizing enzymes (DME) has been determined in male and female Fischer-344 (F344) rats. Arylhydrocarbon hydroxylase (AHH) epoxide hydrolase (EH), glutathione S-transferase (GST) and uridine diphospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6969cda7419c1bb035fd07d5b40940da
https://doi.org/10.1016/0024-3205(80)90518-4
https://doi.org/10.1016/0024-3205(80)90518-4
Publikováno v:
Toxicology and Applied Pharmacology. 81:416-430
Acetaminophen (APAP) produces proximal tubular necrosis in Fischer 344 (F344) rats. Recently, p-aminophenol (PAP), a known potent nephrotoxicant, was identified as a metabolite of APAP in F344 rats. The purpose of this study was to determine if PAP f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beba7838c6124fcad1af09f051e8fee4
https://doi.org/10.1016/0041-008x(85)90413-2
https://doi.org/10.1016/0041-008x(85)90413-2
Autor:
Jerry B. Hook, Chao-Hen Kuo
Publikováno v:
Life Sciences. 33:517-523
Effects of age and sex on hexachloro-1,3-butadiene (HCBD) nephrotoxicity were determined 24 hours after a single dose (0, 25, 50, 100 or 200 mg/kg) in 28- and 63-day-old Fischer 344 rats. HCBD treatment significantly increased the kidney to body weig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e9e8d0ef1b6765665d3474046fe0dc
https://doi.org/10.1016/0024-3205(83)90125-x
https://doi.org/10.1016/0024-3205(83)90125-x
Publikováno v:
Toxicology Letters. 20:23-32
I.p. administration of bromobenzene to male mice at doses ranging from 0 to 9.4 mmol kg resulted in a dose-dependent increase in blood urea nitrogen (BUN) and serum glutamic-pyruvic transaminase (SGPT) activity and a decrease in renal cortical accumu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8c0152d5535323b121487fb16f4599
https://doi.org/10.1016/0378-4274(84)90178-4
https://doi.org/10.1016/0378-4274(84)90178-4
Publikováno v:
Toxicology. 31:343-352
Administration of chloroform (CHCl3) to male C57/6J (C57) and DBA/2J (DBA) mice produced dose-dependent hepatic and renal damage. Hepatic arylhydrocarbon hydroxylase (AHH) activity was higher in C57 than DBA mice; in kidney, AHH activity was higher i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0480af37df7f4869f5f02ece0d71a6
https://doi.org/10.1016/0300-483x(84)90116-1
https://doi.org/10.1016/0300-483x(84)90116-1