Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Chao-Da Xiao"'
Autor:
Xiao-Xia Hu, Sheng-Quan Wang, Shi-Quan Gan, Lei Liu, Ming-Qing Zhong, Meng-Hao Jia, Fei Jiang, Yan Xu, Chao-Da Xiao, Xiang-Chun Shen
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
G-quadruplexes are believed to have important biological functions, so many small molecules have been screened or developed for targeting G-quadruplexes. However, it is still a major challenge to find molecules that recognize specific G-quadruplexes.
Externí odkaz:
https://doaj.org/article/2f20155105b643479e8d937b51fb43c4
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract In this study, by combining nuclear magnetic resonance (NMR), circular dichroism (CD), liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS), and gel electrophoresis, we report an unusual topological structure of the RN
Externí odkaz:
https://doaj.org/article/b9eaae91570446d59a8f828c23d1461d
Publikováno v:
Molecules, Vol 25, Iss 18, p 4339 (2020)
G-quadruplexes are non-canonical four stranded secondary structures possessing great biological importance. Controlling G-quadruplex conformation for further regulating biological processes is both exciting and challenging. In this study, we describe
Externí odkaz:
https://doaj.org/article/843c47c6b80e43bb97b105d655f177a6
Publikováno v:
Molecules, Vol 23, Iss 10, p 2572 (2018)
In contrast to Z-DNA that was stabilized and well-studied for its structure by chemical approaches, the stabilization and structural study of Z-RNA remains a challenge. In this study, we developed a Z-form RNA stabilizer m8Gm, and demonstrated that i
Externí odkaz:
https://doaj.org/article/1982a53347d0447cb125d3ed721a64d2
Autor:
Lei Liu, Wei Zhang, Ming-Qing Zhong, Meng-Hao Jia, Fei Jiang, Yan Zhang, Chao-Da Xiao, Xin Xiao, Xiang-Chun Shen
Publikováno v:
RSC advances. 12(23)
G-Quadruplex (G4), as a non-canonical nucleic acid secondary structure, has been proved to be prevalent in genomes and plays important roles in many biological processes. Ligands targeting G4, especially small-molecular fluorescent light-up probes wi
Publikováno v:
Sensors and Actuators B: Chemical. 366:132006
Publikováno v:
Sensors and Actuators B: Chemical. 354:131189
In this study, tQ[14] based AIE supramolecular network polymers were first constructed through the host-guest interaction between tQ[14] and tetrakis[4-(1-methylpyridin-4-yl) phenyl]ethene iodide (TPE-4P), which display excellent fluorescence propert
Publikováno v:
Journal of the American Chemical Society. 139:2565-2568
Human telomeric RNA performs various cellular functions such as telomere length regulation, heterochromatin formation, and chromosome end protection. Using a combination of nuclear magnetic resonance, circular dichroism, and gel electrophoresis, we o
Publikováno v:
Chemical Communications. 54:3944-3946
Until now, RNA G-quadruplexes were believed to only adopt a parallel G-quadruplex structure. In this study, we describe the first observation of an antiparallel RNA G-quadruplex formed by human telomere RNA. This newly described topology is of great
Autor:
Wang Yi, Li Wanrong, Guoping Wu, Yan Junli, Shen Xiangchun, Jiajia Yang, Min Zhang, Wenli Yao, Wu Linjing, Ting Xiao, Jiang Feng, Zhou Xue, Chao-Da Xiao, Tao Ling, He Zhiyong
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 127
An optimised 1,8-cineole-loaded self-microemulsifying drug delivery system (CIN-SMEDDS) with a mean droplet size, polydispersity index, mean zeta potential and encapsulation efficiency of 38.14 ± 1.47 nm, 0.208 ± 0.036, −9.312 ± 1.764 mV and 95.