Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Chao Chien Chang"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Most proton pump inhibitors (PPIs) inhibit the bioactivation of clopidogrel to its active metabolite. There is controversy concerning whether PPIs alter the effectiveness of clopidogrel in reducing the risk of ischemic stroke (IS). We theref
Externí odkaz:
https://doaj.org/article/3f59e9b92b5642ae9fc9aa53829ec3f3
Autor:
Wei-Chieh Huang, Thanasekaran Jayakumar, Joen-Rong Sheu, Chih-Wei Hsia, Chih-Hsuan Hsia, Ting-Lin Yen, Chao-Chien Chang
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Background Platelets play a crucial role in cardiovascular diseases (CVDs) and are activated by endogenous agonists like collagen. These agonists initiate signal transduction through specific platelet receptors, resulting in platelet aggrega
Externí odkaz:
https://doaj.org/article/08cd4386dd7e433882de1f0309f958d2
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 15 (2021)
Background Heart failure (HF) is a major health problem worldwide because of its high morbidity and mortality. Recently, the role of the microvasculature in HF has gained more attention. Age‐related macular degeneration (AMD) is manifested through
Externí odkaz:
https://doaj.org/article/454e1ca47f1446d5998e50be9f1817f7
Autor:
Yi Chang, Wei-Chieh Huang, Chia-Yuan Hsu, Chih-Wei Hsia, Thanasekaran Jayakumar, Cheng-Ying Hsieh, Wan-Jung Lu, Chao-Chien Chang
Publikováno v:
Applied Sciences, Vol 12, Iss 15, p 7426 (2022)
Metformin is widely used as first-line medication for type 2 diabetes (T2D), the main disease comorbid with kidney disease, cardiovascular diseases (CVDs), and retinopathy. Platelets are crucial in platelet-dependent arterial thrombosis, which causes
Externí odkaz:
https://doaj.org/article/05f82dca96554b92a63d7546fafa9f0b
Autor:
Thanasekaran Jayakumar, Kao-Chang Lin, Chao-Chien Chang, Chih-Wei Hsia, Manjunath Manubolu, Wei-Chieh Huang, Joen-Rong Sheu, Chih-Hsuan Hsia
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 92 (2021)
Studies have discovered that different extracts of Evodia rutaecarpa and its phytochemicals show a variety of biological activities associated with inflammation. Although rutaecarpine, an alkaloid isolated from the unripe fruit of E. rutaecarpa, has
Externí odkaz:
https://doaj.org/article/bc2106614b034ce6bb23b1c8ef182f0b
Publikováno v:
In Journal of Traditional Chinese Medicine June 2017 37(3):326-332
Autor:
Chun-Jen Huang, Wei-Chieh Huang, Wei-Ting Lin, Lan-Hsin Shu, Joen-Rong Sheu, Oanh-Thi Tran, Chih-Wei Hsia, Thanasekaran Jayakumar, Periyakali Saravana Bhavan, Cheng-Ying Hsieh, Chao-Chien Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11109 (2021)
The role of activated platelets in acute and chronic cardiovascular diseases (CVDs) is well established. Therefore, antiplatelet drugs significantly reduce the risk of severe CVDs. Evodia rutaecarpa (Wu-Chu-Yu) is a well-known Chinese medicine, and r
Externí odkaz:
https://doaj.org/article/9345c6e3d7bf4f02afb245f5cc1412ca
Autor:
Thanasekaran Jayakumar, Joen-Rong Sheu, Chih-Wei Hsia, Periyakali Saravana Bhavan, Chao-Chien Chang
Publikováno v:
Applied Sciences, Vol 11, Iss 21, p 10092 (2021)
Inflammation is the primary biological reaction to induce severe infection or injury in the immune system. Control of different inflammatory cytokines, such as nitric oxide (NO), interleukins (IL), tumor necrosis factor alpha-(TNF-α), noncytokine me
Externí odkaz:
https://doaj.org/article/dea28a0aefa949f5ae81a6985c99c4ce
Publikováno v:
Tzu-Chi Medical Journal, Vol 29, Iss 3, Pp 148-153 (2017)
Objective: Hypertension is a risk factor for peripheral artery disease (PAD). Serum leptin plays an important role in promoting endothelial dysfunction. The aim of this study is to investigate whether the leptin level is associated with PAD in hypert
Externí odkaz:
https://doaj.org/article/3b2e37f6048d46a4879be6244a90f95c
Autor:
Chao‐Chien Chang, Kee‐Chin Sia, Jia‐Feng Chang, Chia‐Mo Lin, Chuen‐Mao Yang, I‐Ta Lee, Thi Thuy Tien Vo, Kuo‐Yang Huang, Wei‐Ning Lin
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:3850-3861
Obesity is a world-wide problem, especially the child obesity, with the complication of various metabolic diseases. Child obesity can be developed as early as the age between 2 and 6. The expansion of fat mass in child age includes both hyperplasia a