Výsledky vyhledávání - "Chao, Leslie S."

Akademický článek

CRaTER enrichment for on-target gene editing enables generation of variant libraries in hiPSCs

Autor: Friedman, Clayton E., Fayer, Shawn, Pendyala, Sriram, Chien, Wei-Ming, Loiben, Alexander, Tran, Linda, Chao, Leslie S., Mckinstry, Ashley, Ahmed, Dania, Karbassi, Elaheh, Fenix, Aidan M., Murry, Charles E., Starita, Lea M., Fowler, Douglas M., Yang, Kai-Chun

Publikováno v: In Journal of Molecular and Cellular Cardiology June 2023 179:60-71

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Multiplexed Functional Assessments of MYH7 Variants in Human Cardiomyocytes.

Autor: Friedman CE; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle., Fayer S; Department of Genome Sciences (S.F., S.P., L.M.S., D.M.F.), University of Washington, Seattle., Pendyala S; Department of Genome Sciences (S.F., S.P., L.M.S., D.M.F.), University of Washington, Seattle., Chien WM; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle.; Cardiology/Hospital Specialty Medicine, VA Puget Sound HCS, Seattle, WA (W.-M.C., S.D.F., K.-C.Y.)., Loiben A; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle., Tran L; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle., Chao LS; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle., McKinstry A; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle., Ahmed D; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle., Farris SD; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle.; Cardiology/Hospital Specialty Medicine, VA Puget Sound HCS, Seattle, WA (W.-M.C., S.D.F., K.-C.Y.)., Stempien-Otero A; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle., Jonlin EC; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.)., Murry CE; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle.; Department of Laboratory Medicine and Pathology (C.E.M.), University of Washington, Seattle.; Department of Bioengineering (C.E.M., D.M.F.), University of Washington, Seattle., Starita LM; Department of Genome Sciences (S.F., S.P., L.M.S., D.M.F.), University of Washington, Seattle.; Brotman Baty Institute for Precision Medicine, Seattle, WA (L.M.S., D.M.F.)., Fowler DM; Department of Genome Sciences (S.F., S.P., L.M.S., D.M.F.), University of Washington, Seattle.; Department of Bioengineering (C.E.M., D.M.F.), University of Washington, Seattle.; Brotman Baty Institute for Precision Medicine, Seattle, WA (L.M.S., D.M.F.)., Yang KC; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., E.C.J., C.E.M., K.-C.Y.).; Center for Cardiovascular Biology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y), University of Washington, Seattle.; Department of Medicine/Cardiology (C.E.F., W.-M.C., A.L., L.T., L.S.C., A.M., D.A., S.D.F., A.S.-O., C.E.M., K.-C.Y.), University of Washington, Seattle.; Cardiology/Hospital Specialty Medicine, VA Puget Sound HCS, Seattle, WA (W.-M.C., S.D.F., K.-C.Y.).

Publikováno v: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2024 Apr; Vol. 17 (2), pp. e004377. Date of Electronic Publication: 2024 Feb 16.

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Cardiomyocyte apoptosis contributes to contractile dysfunction in stem cell model of MYH7 E848G hypertrophic cardiomyopathy.

Autor: Loiben AM; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA., Chien WM; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA.; Cardiology/Hospital Specialty Medicine, VA Puget Sound HCS, Seattle, WA, USA., Friedman CE; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA., Chao LS; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA., Weber G; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA., Goldstein A; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA.; Department of Mechanical Engineering, University of Washington, Seattle, WA, USA.; Department of Lab Medicine and Pathology, University of Washington, Seattle, WA, USA., Sniadecki N; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA.; Department of Mechanical Engineering, University of Washington, Seattle, WA, USA.; Department of Bioengineering, University of Washington, Seattle, WA, USA.; Department of Lab Medicine and Pathology, University of Washington, Seattle, WA, USA., Murry CE; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA.; Department of Bioengineering, University of Washington, Seattle, WA, USA.; Department of Lab Medicine and Pathology, University of Washington, Seattle, WA, USA., Yang KC; Institute for Stem Cell and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.; Department of Medicine/Cardiology, University of Washington, Seattle, WA, USA.; Cardiology/Hospital Specialty Medicine, VA Puget Sound HCS, Seattle, WA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jan 25. Date of Electronic Publication: 2023 Jan 25.

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