Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Chanthirika, Ragulan"'
Autor:
Jessica Burns, Christopher P. Wilding, Lukas Krasny, Xixuan Zhu, Madhumeeta Chadha, Yuen Bun Tam, Hari PS, Aswanth H. Mahalingam, Alexander T. J. Lee, Amani Arthur, Nafia Guljar, Emma Perkins, Valeriya Pankova, Andrew Jenks, Vanessa Djabatey, Cornelia Szecsei, Frank McCarthy, Chanthirika Ragulan, Martina Milighetti, Theodoros I. Roumeliotis, Stephen Crosier, Martina Finetti, Jyoti S. Choudhary, Ian Judson, Cyril Fisher, Eugene F. Schuster, Anguraj Sadanandam, Tom W. Chen, Daniel Williamson, Khin Thway, Robin L. Jones, Maggie C. U. Cheang, Paul H. Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of tumour specimens from 321 STS patients representing 11 histological subtypes. Within l
Externí odkaz:
https://doaj.org/article/9d213184d1a64b60a226a35cf5a6990a
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/cf9a788148764fcf99732575130f6ee8
Autor:
Aruna Korlimarla, PS Hari, Jyoti Prabhu, Chanthirika Ragulan, Yatish Patil, VP Snijesh, Krisha Desai, Aju Mathews, Sandhya Appachu, Ravi B. Diwakar, BS Srinath, Alan Melcher, Maggie Cheang, Anguraj Sadanandam
Publikováno v:
Translational Oncology, Vol 27, Iss , Pp 101574- (2023)
Externí odkaz:
https://doaj.org/article/8af7d49800d6483188b46b69120e86c7
Autor:
Aruna Korlimarla, Hari PS, Jyoti Prabhu, Chanthirika Ragulan, Yatish Patil, Snijesh VP, Krisha Desai, Aju Mathews, Sandhya Appachu, Ravi B. Diwakar, Srinath BS, Alan Melcher, Maggie Cheang, Anguraj Sadanandam
Publikováno v:
Translational Oncology, Vol 25, Iss , Pp 101511- (2022)
Purpose: Triple-negative breast cancer (TNBC) is a heterogeneous disease with a significant challenge to effectively manage in the clinic worldwide. Immunotherapy may be beneficial to TNBC patients if responders can be effectively identified. Here we
Externí odkaz:
https://doaj.org/article/a88adf8242244906823d8dcfed4bdb5f
Autor:
Zeribe C. Nwosu, Matthew H. Ward, Peter Sajjakulnukit, Pawan Poudel, Chanthirika Ragulan, Steven Kasperek, Megan Radyk, Damien Sutton, Rosa E. Menjivar, Anthony Andren, Juan J. Apiz-Saab, Zachary Tolstyka, Kristee Brown, Ho-Joon Lee, Lindsey N. Dzierozynski, Xi He, Hari PS, Julia Ugras, Gift Nyamundanda, Li Zhang, Christopher J. Halbrook, Eileen S. Carpenter, Jiaqi Shi, Leah P. Shriver, Gary J. Patti, Alexander Muir, Marina Pasca di Magliano, Anguraj Sadanandam, Costas A. Lyssiotis
Publikováno v:
Nature, vol 618, iss 7963
Pancreatic ductal adenocarcinoma (PDA) is a lethal disease notoriously resistant to therapy1,2. This is mediated in part by a complex tumour microenvironment3, low vascularity4, and metabolic aberrations5,6. Although altered metabolism drives tumour
Autor:
Elisa Fontana, Anguraj Sadanandam, Paul Carter, Nick West, Sandra Demaria, Kevin Harrington, Alan Melcher, David Mansfield, Katharina von Loga, Fiona Errington-Mais, Anna Wilkins, Gift Nyamundanda, Hannah Bye, Chanthirika Ragulan, Yatish Patil, Jennifer Kingston, Daniel Bottomley, Emma Tinkler-Hundal, Jessica Downs, Magnus Dillon, David Sebag-Montefiore, Arish Noshirwani
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Rectal cancers show a highly varied response to neoadjuvant radiotherapy/chemoradiation (RT/CRT) and the impact of the tumor immune microenvironment on this response is poorly understood. Current clinical tumor regression grading systems a
Externí odkaz:
https://doaj.org/article/48882b43944f4a79aa411b08dcce06cb
Autor:
Kevin J. Harrington, Martin McLaughlin, Alan Melcher, Anguraj Sadanandam, Anna C. Wilkins, Krisha Desai, Elisa Fontana, Chanthirika Ragulan, Galabina Bozhanova, Shane Foo, Radhika R. Patel, James T.E. Paget, Henry G. Smith, Alex Pearson, Emmanuel C. Patin, Eva Crespo-Rodriguez, Harriet Whittock, Malin Pedersen, Katharina F. Bergerhoff, Magnus T. Dillon
Purpose:ATR inhibitors (ATRi) are in early phase clinical trials and have been shown to sensitize to chemotherapy and radiotherapy preclinically. Limited data have been published about the effect of these drugs on the tumor microenvironment.Experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4954af3c614c3181d2ace55e502316ce
https://doi.org/10.1158/1078-0432.c.6527228.v1
https://doi.org/10.1158/1078-0432.c.6527228.v1
Autor:
Kevin J. Harrington, Martin McLaughlin, Alan Melcher, Anguraj Sadanandam, Anna C. Wilkins, Krisha Desai, Elisa Fontana, Chanthirika Ragulan, Galabina Bozhanova, Shane Foo, Radhika R. Patel, James T.E. Paget, Henry G. Smith, Alex Pearson, Emmanuel C. Patin, Eva Crespo-Rodriguez, Harriet Whittock, Malin Pedersen, Katharina F. Bergerhoff, Magnus T. Dillon
Supplementary figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e78d734f34504452c9609a08573d068
https://doi.org/10.1158/1078-0432.22469357
https://doi.org/10.1158/1078-0432.22469357
Autor:
Aruna Korlimarla, PS Hari, Jyoti Prabhu, Chanthirika Ragulan, Yatish Patil, VP Snijesh, Krisha Desai, Aju Mathews, Sandhya Appachu, Ravi B. Diwakar, BS Srinath, Maggie Cheang, Anguraj Sadanandam
BackgroundTriple-negative breast cancer (TNBC) is a heterogeneous disease with a significant clinical challenge. TNBC alarmingly comprises 25-30% of breast cancers in India compared with only 10-15% in the West. However, immunotherapy was approved fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41218f739a5fc7fe90eebb5dd0d0ac59
https://doi.org/10.1101/2022.03.06.483159
https://doi.org/10.1101/2022.03.06.483159
Autor:
Marina Pasca di Magliano, Christopher J. Halbrook, Chanthirika Ragulan, Anguraj Sadanandam, Gift Nyamundanda, Li Zhang, Eileen S. Carpenter, Anthony Andren, Costas A. Lyssiotis, Matthew H. Ward, Steven Kasperek, Zeribe C. Nwosu, Rosa E. Menjivar, Zach Tolstyka, Pawan Poudel
Pancreatic ductal adenocarcinoma (PDA) is a lethal disease characterized by high invasiveness, therapeutic resistance, and metabolic aberrations. Although altered metabolism drives PDA growth and survival, the complete spectrum of metabolites used as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0b4ce56bccda25f9c66aa5cbb6c4ff9
https://doi.org/10.1101/2021.06.07.447448
https://doi.org/10.1101/2021.06.07.447448