Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Chantal Prévost"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14896 (2023)
Homologous recombination (HR) is a fundamental process common to all species. HR aims to faithfully repair DNA double strand breaks. HR involves the formation of nucleoprotein filaments on DNA single strands (ssDNA) resected from the break. The nucle
Externí odkaz:
https://doaj.org/article/6126615b19564d1cb19bf7066f009c92
Autor:
Mara Prentiss, Dianzhuo Wang, Jonathan Fu, Chantal Prévost, Veronica Godoy-Carter, Nancy Kleckner, Claudia Danilowicz
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288611 (2023)
In E. coli, double strand breaks (DSBs) are resected and loaded with RecA protein. The genome is then rapidly searched for a sequence that is homologous to the DNA flanking the DSB. Mismatches in homologous partners are rare, suggesting that RecA sho
Externí odkaz:
https://doaj.org/article/1bcd6cbdcd8f43f0a1c3f713f1e07764
Autor:
Anne-Elisabeth Molza, Yvonne Westermaier, Magali Moutte, Pierre Ducrot, Claudia Danilowicz, Veronica Godoy-Carter, Mara Prentiss, Charles H. Robert, Marc Baaden, Chantal Prévost
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Recent advances in structural biophysics and integrative modelling methods now allow us to decipher the structures of large macromolecular assemblies. Understanding the dynamics and mechanisms involved in their biological function requires rigorous i
Externí odkaz:
https://doaj.org/article/cbb8e3ac6752421ebb24cb7700b5bdd9
Publikováno v:
Bio-Protocol, Vol 11, Iss 14 (2021)
Protein filaments are dynamic entities that respond to external stimuli by slightly or substantially modifying the internal binding geometries between successive protomers. This results in overall changes in the filament architecture, which are diffi
Externí odkaz:
https://doaj.org/article/36d47cf4de534f6b86a1541432202c12
Publikováno v:
Molecules, Vol 27, Iss 6, p 1841 (2022)
Protein–protein assemblies act as a key component in numerous cellular processes. Their accurate modeling at the atomic level remains a challenge for structural biology. To address this challenge, several docking and a handful of deep learning meth
Externí odkaz:
https://doaj.org/article/3fcb87d98fc94b7f9c41530daf2ade14
Autor:
Sophie Sacquin-Mora, Chantal Prévost
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1529 (2021)
The degree of proteins structural organization ranges from highly structured, compact folding to intrinsic disorder, where each degree of self-organization corresponds to specific functions: well-organized structural motifs in enzymes offer a proper
Externí odkaz:
https://doaj.org/article/859cf5efbbc8429d8c172d8fbfee0009
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 2, Pp 1316-1333 (2011)
Rapid progress of theoretical methods and computer calculation resources has turned in silico methods into a conceivable tool to predict the 3D structure of macromolecular assemblages, starting from the structure of their separate elements. Still, so
Externí odkaz:
https://doaj.org/article/720c5522dfe24f8fa02f27a6566d3469
An integrative approach to the study of filamentous oligomeric assemblies, with application to RecA.
Autor:
Benjamin Boyer, Johann Ezelin, Pierre Poulain, Adrien Saladin, Martin Zacharias, Charles H Robert, Chantal Prévost
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0116414 (2015)
Oligomeric macromolecules in the cell self-organize into a wide variety of geometrical motifs such as helices, rings or linear filaments. The recombinase proteins involved in homologous recombination present many such assembly motifs. Here, we examin
Externí odkaz:
https://doaj.org/article/d6ca1d7e556c408fb0e0e1edceaa3832
The microtubule-associated protein (MAP) tau plays a key role in the regulation of microtubule assembly and spatial organisation. Tau hyperphosphorylation affects its binding on the tubulin surface and has been shown to be involved in several patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5b69df475f875a0ed212d2abc828846
https://doi.org/10.1101/2023.02.09.527845
https://doi.org/10.1101/2023.02.09.527845
RecA balances genomic stability and evolution using many successive mismatch tolerant homology tests
Autor:
Mara Prentiss, John Wang, Jonathan Fu, Chantal Prévost, Veronica Godoy-Carter, Nancy Kleckner, Claudia Danilowicz
A double-strand break (DSB) must usually be repaired with as little alteration to the genome as possible, though some rare alterations provide valuable genomic evolution. InE.coli, a DSB undergoes resection to give 3’ ssDNA tails. These invading st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88d04ead915d39e6408799edd552e54f
https://doi.org/10.1101/2022.12.09.519633
https://doi.org/10.1101/2022.12.09.519633