Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Chantal Pauli"'
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Backrgound Merkel cell carcinoma (MCC) is a rare, aggressive primary cutaneous neuroendocrine carcinoma, frequently associated with clonal Merkel cell polyomavirus integration. MCC can pose significant diagnostic challenges due to its divers
Externí odkaz:
https://doaj.org/article/454cba4a3113406a80c8c8b5880d9273
Autor:
Lilian Roth, Linda Huynh-Russo, Laura Heeb, Sima Ulugöl, Rafael Freire Dos Santos, Eva Breuer, Udo Ungethüm, Martina Haberecker, Chantal Pauli, Viktor Koelzer, Kuno Lehmann, Anurag Gupta
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Multimodal therapy for peritoneal metastasis (PM) including cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provides long-term survival in highly selected colorectal cancer patients. Mechanisms behind HIPEC
Externí odkaz:
https://doaj.org/article/fad11af395664b6181c3d0cec33526fd
Autor:
Sam G. Edalat, Reto Gerber, Miranda Houtman, Janine Lückgen, Rui Lourenço Teixeira, Maria del Pilar Palacios Cisneros, Tamara Pfanner, Tadeja Kuret, Nadja Ižanc, Raphael Micheroli, Joaquim Polido-Pereira, Fernando Saraiva, Swathi Lingam, Kristina Burki, Blaž Burja, Chantal Pauli, Žiga Rotar, Matija Tomšič, Saša Čučnik, João Eurico Fonseca, Oliver Distler, Ângelo Calado, Vasco C. Romão, Caroline Ospelt, Snežna Sodin-Semrl, Mark D. Robinson, Mojca Frank Bertoncelj
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109707- (2024)
Summary: In this study, we optimized the dissociation of synovial tissue biopsies for single-cell omics studies and created a single-cell atlas of human synovium in inflammatory arthritis. The optimized protocol allowed consistent isolation of highly
Externí odkaz:
https://doaj.org/article/4949afb345a94708b58cea17f6bb5dbc
The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis
Autor:
Muriel Elhai, Raphael Micheroli, Miranda Houtman, Masoumeh Mirrahimi, Larissa Moser, Chantal Pauli, Kristina Bürki, Andrea Laimbacher, Gabriela Kania, Kerstin Klein, Philipp Schätzle, Mojca Frank Bertoncelj, Sam G. Edalat, Leandra Keusch, Alexandra Khmelevskaya, Melpomeni Toitou, Celina Geiss, Thomas Rauer, Maria Sakkou, George Kollias, Marietta Armaka, Oliver Distler, Caroline Ospelt
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Although patients with rheumatoid arthritis (RA) typically exhibit symmetrical joint involvement, some patients develop alternative disease patterns in response to treatment, suggesting that different molecular mechanism may underlie disease
Externí odkaz:
https://doaj.org/article/69a704ad8e714379b5b6e4a46b31ca7a
Autor:
Patricia Beer, Chantal Pauli, Martina Haberecker, Paula Grest, Erin Beebe, Daniel Fuchs, Enni Markkanen, Christiane Krudewig, Mirja Christine Nolff
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionComplete surgical tumor resection is paramount in the management of soft tissue sarcoma (STS) in humans, dogs, and cats alike. Near-infrared targeted tracers for fluorescence-guided surgery (FGS) could facilitate intraoperative visualizat
Externí odkaz:
https://doaj.org/article/28e4155deaed4c03bc20cce0eb443212
Autor:
Lara Planas‐Paz, Alicia Pliego‐Mendieta, Catherine Hagedorn, Domingo Aguilera‐Garcia, Martina Haberecker, Fabian Arnold, Marius Herzog, Lorenz Bankel, Roman Guggenberger, Sabrina Steiner, Yanjiang Chen, Abdullah Kahraman, Martin Zoche, Mark A Rubin, Holger Moch, Christian Britschgi, Chantal Pauli
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 4, Pp 1-21 (2023)
Abstract Defects in homologous recombination repair (HRR) in tumors correlate with poor prognosis and metastases development. Determining HRR deficiency (HRD) is of major clinical relevance as it is associated with therapeutic vulnerabilities and rem
Externí odkaz:
https://doaj.org/article/d874520ba4d8464eacd895ed33371d67
Autor:
Marco M. Bühler, Hanna Honcharova-Biletska, Chantal Pauli, Dimitrios Chronas, Kristina Bolten
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101233- (2023)
In depth molecular studies are constantly expanding our understanding and refining the classification of gynecological neoplasms. NTRK rearranged spindle cell neoplasms of the lower genital tract are an emerging entity, of particular interest due to
Externí odkaz:
https://doaj.org/article/3face2c61a404f9dacc4fa3b5e60d42a
Autor:
Oliver Distler, Adrian Ciurea, Caroline Ospelt, Raphael Micheroli, Kristina Bürki, Chantal Pauli, Philipp Rossbach
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/e26f68f63f024fc491f5f22832b07fc6
Autor:
Christian K. Hirt, Tijmen H. Booij, Linda Grob, Patrik Simmler, Nora C. Toussaint, David Keller, Doreen Taube, Vanessa Ludwig, Alexander Goryachkin, Chantal Pauli, Daniela Lenggenhager, Daniel J. Stekhoven, Christian U. Stirnimann, Katharina Endhardt, Femke Ringnalda, Lukas Villiger, Alexander Siebenhüner, Sofia Karkampouna, Marta De Menna, Janette Beshay, Hagen Klett, Marianna Kruithof-de Julio, Julia Schüler, Gerald Schwank
Publikováno v:
Cell Genomics, Vol 2, Iss 2, Pp 100095- (2022)
Summary: Pancreatic cancer (PDAC) is a highly aggressive malignancy for which the identification of novel therapies is urgently needed. Here, we establish a human PDAC organoid biobank from 31 genetically distinct lines, covering a representative ran
Externí odkaz:
https://doaj.org/article/528029a5e0b440e9b617944420259540
Autor:
Loredana Puca, Rohan Bareja, Davide Prandi, Reid Shaw, Matteo Benelli, Wouter R. Karthaus, Judy Hess, Michael Sigouros, Adam Donoghue, Myriam Kossai, Dong Gao, Joanna Cyrta, Verena Sailer, Aram Vosoughi, Chantal Pauli, Yelena Churakova, Cynthia Cheung, Lesa Dayal Deonarine, Terra J. McNary, Rachele Rosati, Scott T. Tagawa, David M. Nanus, Juan Miguel Mosquera, Charles L. Sawyers, Yu Chen, Giorgio Inghirami, Rema A. Rao, Carla Grandori, Olivier Elemento, Andrea Sboner, Francesca Demichelis, Mark A. Rubin, Himisha Beltran
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
There are few available models to study neuroendocrine prostate cancer. Here they develop and characterize patient derived organoids from metastatic lesions, use these models to show the role of EZH2 in driving neuroendocrine phenotype, and perform h
Externí odkaz:
https://doaj.org/article/6298c3191ca44642a1ee5adc286008a4