Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Chantal Mattman"'
Publikováno v:
International Immunology, vol. 8, no. 1, pp. 57-63
Cytolytic T lymphocytes kill target cells by two independent cytolytic mechanisms. One pathway depends on the polarized secretion of granule-stored proteins including perforin and granzymes, causing target cell death through membrane and DNA damage.
Autor:
Kristina Ludigs, Queralt Seguín-Estévez, Sylvain Lemeille, Isabel Ferrero, Giorgia Rota, Sonia Chelbi, Chantal Mattmann, H Robson MacDonald, Walter Reith, Greta Guarda
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005088 (2015)
MHC class II (MHCII) genes are transactivated by the NOD-like receptor (NLR) family member CIITA, which is recruited to SXY enhancers of MHCII promoters via a DNA-binding "enhanceosome" complex. NLRC5, another NLR protein, was recently found to contr
Externí odkaz:
https://doaj.org/article/43e60c513221439798aebe7744bcb1a6