Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots.

Autor: Emily E Wear, Jawon Song, Gregory J Zynda, Leigh Mickelson-Young, Chantal LeBlanc, Tae-Jin Lee, David O Deppong, George C Allen, Robert A Martienssen, Matthew W Vaughn, Linda Hanley-Bowdoin, William F Thompson

Publikováno v: PLoS Genetics, Vol 16, Iss 10, p e1008623 (2020)

Plant cells undergo two types of cell cycles-the mitotic cycle in which DNA replication is coupled to mitosis, and the endocycle in which DNA replication occurs in the absence of cell division. To investigate DNA replication programs in these two typ

Externí odkaz: https://doaj.org/article/d95231f4b73940138ebe1343c36485a7

The Arabidopsis thaliana mobilome and its impact at the species level

Autor: Leandro Quadrana, Amanda Bortolini Silveira, George F Mayhew, Chantal LeBlanc, Robert A Martienssen, Jeffrey A Jeddeloh, Vincent Colot

Publikováno v: eLife, Vol 5 (2016)

Transposable elements (TEs) are powerful motors of genome evolution yet a comprehensive assessment of recent transposition activity at the species level is lacking for most organisms. Here, using genome sequencing data for 211 Arabidopsis thaliana ac

Externí odkaz: https://doaj.org/article/37db690129af43ceaadf65d865f1cd8c

The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication

Autor: Hossein Davarinejad, Yi-Chun Huang, Benoit Mermaz, Chantal LeBlanc, Axel Poulet, Geoffrey Thomson, Valentin Joly, Marcelo Muñoz, Alexis Arvanitis-Vigneault, Devisree Valsakumar, Gonzalo Villarino, Alex Ross, Benjamin H. Rotstein, Emilio I. Alarcon, Joseph S. Brunzelle, Philipp Voigt, Jie Dong, Jean-François Couture, Yannick Jacob

Publikováno v: Science
Davarinejad, H, Huang, Y-C, Mermaz, B, Leblanc, C, Poulet, A, Thomson, G, Joly, V, Muñoz, M, Arvanitis-Vigneault, A, Valsakumar, D, Villarino, G, Ross, A, Rotstein, B H, Alarcon, E I, Brunzelle, J S, Voigt, P, Dong, J, Couture, J-F & Jacob, Y 2022, ' The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication ', Science, vol. 375, no. 6586, pp. 1281-1286 . https://doi.org/10.1126/science.abm5320

The tail of replication-dependent histone H3.1 varies from that of replication-independent H3.3 at the amino acid located at position 31 in plants and animals, but no function has been assigned to this residue to demonstrate a unique and conserved ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9ac8d5b667a21faac2d0bd5e313c09
https://doi.org/10.1126/science.abm5320

Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin

Autor: Elin Axelsson, Daniel Buendía, Michael Borg, Tetsuya Higashiyama, Leonor C. Boavida, Yannick Jacob, Frédéric Berger, Chantal LeBlanc, Jörg Becker, Philipp Voigt, Robert A. Martienssen, Daichi Susaki, Tomokazu Kawashima

Publikováno v: Nat Cell Biol
Borg, M, Jacob, Y, Susaki, D, LeBlanc, C, Buendía, D, Axelsson, E, Kawashima, T, Voigt, P, Boavida, L, Becker, J, Higashiyama, T, Martienssen, R & Berger, F 2020, ' Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin ', Nature Cell Biology, vol. 22, no. 6, pp. 621-629 . https://doi.org/10.1038/s41556-020-0515-y

Epigenetic marks are reprogrammed in the gametes to reset genomic potential in the next generation. In mammals, paternal chromatin is extensively reprogrammed through the global erasure of DNA methylation and the exchange of histones with protamines1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428ed3bdeca7b4cf526576bccb2ab849
https://doi.org/10.1038/s41556-020-0515-y

H3.1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation

Autor: Benoit Mermaz, Yannick Jacob, Gonzalo H. Villarino, Philipp Voigt, Josefina Mendez, Kimberly M. Webb, Axel Poulet, Valentin Joly, Jie Dong, Chantal LeBlanc

Publikováno v: Dong, J, LeBlanc, C, Poulet, A, Mermaz, B, Villarino, G, Webb, K M, Joly, V, Mendez, J, Voigt, P & Jacob, Y 2021, ' H3.1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation ', Plant Cell, vol. 33, no. 4, koaa027, pp. 961–979 . https://doi.org/10.1093/plcell/koaa027
bioRxiv
Plant Cell

Epigenetic mechanisms play diverse roles in the regulation of genome stability in eukaryotes. In Arabidopsis thaliana, genome stability is maintained during DNA replication by the H3.1K27 methyltransferases ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (AT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0101cf33a51c29ac38a4f9e057a7fa8
https://www.pure.ed.ac.uk/ws/files/203917165/TPC2020_RA_00608R2_00608_Merged.pdf