Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Chantal L. Bachmann"'
Autor:
Ramin Radpour, Ursina Lüthi, Gabriela M. Baerlocher, Sven Hoppe, Nils Maria Kallen, Damian T. Bürgin, Christian M. Schürch, Miroslav Arambasic, Christoph E. Albers, Carsten Riether, Adrian F. Ochsenbein, Chantal L. Bachmann
Publikováno v:
Riether, Carsten; Radpour, Ramin; Kallen, Nils M.; Bürgin, Damian T.; Bachmann, Chantal; Schürch, Christian M.; Lüthi, Ursina; Arambasic, Miroslav; Hoppe, Sven; Albers, Christoph E.; Baerlocher, Gabriela M.; Ochsenbein, Adrian (2021). Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells. Cell reports, 34(4), p. 108663. Cell Press 10.1016/j.celrep.2020.108663
Summary Self-renewal is a key characteristic of leukemia stem cells (LSCs) responsible for the development and maintenance of leukemia. In this study, we identify CD93 as an important regulator of self-renewal and proliferation of murine and human LS
Autor:
Miroslav Arambasic, Ramin Radpour, Christian M. Schürch, Gabriela M. Baerlocher, Chantal L. Bachmann, Adrian F. Ochsenbein, Carsten Riether
Publikováno v:
Blood. 134:187-187
Background: The introduction of BCR/ABL-specific tyrosine kinase inhibitors (TKIs) more than two decades ago revolutionized chronic myelogenous leukemia (CML) therapy. The majority of CML patients treated with TKIs obtain durable cytogenetic and mole