Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chantal J.M. Van Opbergen"'
Autor:
Marta Pérez-Hernández, Chantal J.M. van Opbergen, Navratan Bagwan, Christoffer Rasmus Vissing, Grecia M. Marrón-Liñares, Mingliang Zhang, Estefania Torres Vega, Andrea Sorrentino, Lylia Drici, Karolina Sulek, Ruxu Zhai, Finn B. Hansen, Alex Hørby Christensen, Søren Boesgaard, Finn Gustafsson, Kasper Rossing, Eric M. Small, Michael J. Davies, Eli Rothenberg, Priscila Y. Sato, Marina Cerrone, Thomas Hartvig Lindkær Jensen, Klaus Qvortrup, Henning Bundgaard, Mario Delmar, Alicia Lundby
Publikováno v:
Circulation. 146(11)
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by high propensity to life-threatening arrhythmias and progressive loss of heart muscle. More than 40% of reported genetic variants linked to ARVC reside in the PKP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edd7414fa4b54f3858bd75e129cda12
https://pubmed.ncbi.nlm.nih.gov/35959657
https://pubmed.ncbi.nlm.nih.gov/35959657
Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm
Autor:
Marina Cerrone, Jerome Montnach, Xianming Lin, Yan-Ting Zhao, Mingliang Zhang, Esperanza Agullo-Pascual, Alejandra Leo-Macias, Francisco J. Alvarado, Igor Dolgalev, Thomas V. Karathanos, Kabir Malkani, Chantal J.M. Van Opbergen, Joanne J.A. van Bavel, Hua-Qian Yang, Carolina Vasquez, David Tester, Steven Fowler, Fengxia Liang, Eli Rothenberg, Adriana Heguy, Gregory E. Morley, William A. Coetzee, Natalia A. Trayanova, Michael J. Ackerman, Toon A.B. van Veen, Hector H. Valdivia, Mario Delmar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
It is believed that mutations in desmosomal adhesion complex protein plakophilin 2 (PKP2) cause arrhythmia due to loss of cell-cell communication. Here the authors show that PKP2 controls the expression of proteins involved in calcium cycling in adul
Externí odkaz:
https://doaj.org/article/4417834a57fb40c18499881ece963bc6
Publikováno v:
Circulation Research. 130:725-727
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b191441dd06157a8fad5673f0527c00f
https://doi.org/10.1161/circresaha.122.320798
https://doi.org/10.1161/circresaha.122.320798
Autor:
Chantal J.M. van Opbergen, Maartje Noorman, Anna Pfenniger, Jaël S. Copier, Sarah H. Vermij, Zhen Li, Roel van der Nagel, Mingliang Zhang, Jacques M.T. de Bakker, Aaron M. Glass, Peter J. Mohler, Steven M. Taffet, Marc A. Vos, Harold V.M. van Rijen, Mario Delmar, Toon A.B. van Veen
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4076 (2019)
Human variants in plakophilin-2 (PKP2) associate with most cases of familial arrhythmogenic cardiomyopathy (ACM). Recent studies show that PKP2 not only maintains intercellular coupling, but also regulates transcription of genes involved in Ca2+ cycl
Externí odkaz:
https://doaj.org/article/3524f74346104ca29ffea14b78d8a22e
Autor:
Chantal J.M. van Opbergen, Navratan Bagwan, Svetlana R. Maurya, Joon-Chul Kim, Abigail N. Smith, Daniel J. Blackwell, Jeffrey N. Johnston, Björn C. Knollmann, Marina Cerrone, Alicia Lundby, Mario Delmar
Publikováno v:
Circulation
Van Opbergen, C J M, Bagwan, N, Maurya, S R, Kim, J C, Smith, A N, Blackwell, D J, Johnston, J N, Knollmann, B C, Cerrone, M, Lundby, A & Delmar, M 2022, ' Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts ', Circulation, vol. 145, no. 19, pp. 1480-1496 . https://doi.org/10.1161/CIRCULATIONAHA.121.057757
Van Opbergen, C J M, Bagwan, N, Maurya, S R, Kim, J C, Smith, A N, Blackwell, D J, Johnston, J N, Knollmann, B C, Cerrone, M, Lundby, A & Delmar, M 2022, ' Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts ', Circulation, vol. 145, no. 19, pp. 1480-1496 . https://doi.org/10.1161/CIRCULATIONAHA.121.057757
Background: Exercise training, and catecholaminergic stimulation, increase the incidence of arrhythmic events in patients affected with arrhythmogenic right ventricular cardiomyopathy correlated with plakophilin-2 (PKP2) mutations. Separate data show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d75342d9dbc919b43db6dae713acc6f
https://europepmc.org/articles/PMC9086182/
https://europepmc.org/articles/PMC9086182/
Autor:
Chantal J.M. van Opbergen, Alison Smith, Rakesh R. Maurya, Duk Jae Kim, Alison N. Smith, Darren J. Blackwell, Jeffrey N. Johnston, Bjorn C. Knollmann, Marina Cerrone, Alicia Lundby, Mario Delmar
Publikováno v:
Heart Rhythm. 19:S99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b3d7814c29d5f9142028960be6db5c2
https://doi.org/10.1016/j.hrthm.2022.03.775
https://doi.org/10.1016/j.hrthm.2022.03.775
Publikováno v:
Microscopy & Microanalysis; 2022 Supplement, Vol. 28, p1448-1449, 2p
Autor:
Pérez-Hernández, Marta, van Opbergen, Chantal J.M., Bagwan, Navratan, Vissing, Christoffer Rasmus, Marrón-Liñares, Grecia M., Zhang, Mingliang, Torres Vega, Estefania, Sorrentino, Andrea, Drici, Lylia, Sulek, Karolina, Zhai, Ruxu, Hansen, Finn B., Hørby Christensen, Alex, Boesgaard, Søren, Gustafsson, Finn, Rossing, Kasper, Small, Eric M., Davies, Michael J., Rothenberg, Eli, Sato, Priscila Y.
Publikováno v:
Circulation; 9/13/2022, Vol. 146 Issue 11, p851-867, 17p
Autor:
van Opbergen, Chantal J.M., Bagwan, Navratan, Maurya, Svetlana R., Kim, Joon-Chul, Smith, Abigail N., Blackwell, Daniel J., Johnston, Jeffrey N., Knollmann, Björn C., Cerrone, Marina, Lundby, Alicia, Delmar, Mario
Publikováno v:
Circulation; 5/10/2022, Vol. 145 Issue 19, p1480-1496, 17p