Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Chantal Gauthier"'
Autor:
Justyna Ciolek, Claude Zoukimian, Justine Dhot, Mélanie Burban, Mathilde Triquigneaux, Benjamin Lauzier, Christelle Guimbert, Didier Boturyn, Marine Ferron, Lidia Ciccone, Livia Tepshi, Enrico Stura, Pierre Legrand, Philippe Robin, Gilles Mourier, Béatrice Schaack, Imen Fellah, Guillaume Blanchet, Chantal Gauthier-Erfanian, Rémy Beroud, Denis Servent, Michel De Waard, Nicolas Gilles
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 150, Iss , Pp 113094- (2022)
All five muscarinic receptors have important physiological roles. The endothelial M2 and M3 subtypes regulate arterial tone through direct coupling to Gq or Gi/o proteins. Yet, we lack selective pharmacological drugs to assess the respective contribu
Externí odkaz:
https://doaj.org/article/81fb19f4b1464cb2be0363e9765a0645
Autor:
Justine Dhot, Marine Ferron, Valentine Prat, Antoine Persello, David Roul, David Stévant, Damien Guijarro, Nicolas Piriou, Virginie Aillerie, Angélique Erraud, Gilles Toumaniantz, Morteza Erfanian, Angela Tesse, Amandine Grabherr, Laurent Tesson, Séverine Menoret, Ignacio Anegon, Jean‐Noël Trochu, Marja Steenman, Michel De Waard, Bertrand Rozec, Benjamin Lauzier, Chantal Gauthier
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 4159-4171 (2020)
Abstract Aims Diastolic dysfunction is common in cardiovascular diseases, particularly in the case of heart failure with preserved ejection fraction. The challenge is to develop adequate animal models to envision human therapies in the future. It has
Externí odkaz:
https://doaj.org/article/303759f709374a3a807f6f14fd31e462
Autor:
Roselle Gélinas, Florence Mailleux, Justine Dontaine, Laurent Bultot, Bénédicte Demeulder, Audrey Ginion, Evangelos P. Daskalopoulos, Hrag Esfahani, Emilie Dubois-Deruy, Benjamin Lauzier, Chantal Gauthier, Aaron K. Olson, Bertrand Bouchard, Christine Des Rosiers, Benoit Viollet, Kei Sakamoto, Jean-Luc Balligand, Jean-Louis Vanoverschelde, Christophe Beauloye, Sandrine Horman, Luc Bertrand
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
AMPK activation inhibits cardiac hypertrophy. Here the authors show that this occurs independently of previously proposed mechanisms and that AMPK controls the phosphorylation of the aminotransferase GFAT, thereby preventing cardiac hypertrophy throu
Externí odkaz:
https://doaj.org/article/46a09b637dfb42aab34016e0737a3bb6
Autor:
Justine Dhot, Valentine Prat, Marine Ferron, Virginie Aillerie, Angélique Erraud, Bertrand Rozec, Michel De Waard, Chantal Gauthier, Benjamin Lauzier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 774 (2021)
The use of animal models in fundamental or pre-clinical research remains an absolute requirement for understanding human pathologies and developing new drugs. In order to transpose these results into clinical practice, many parameters must be taken i
Externí odkaz:
https://doaj.org/article/fb13ef1bb2de4a32bc77d7028e293504
Autor:
Hatsumi Yoshiki, Atsushi Nishimune, Fumiko Suzuki, Shigeru Morishima, Takeshi Ikeda, Masato Sasaki, Leslie M. Audigane, Chantal Gauthier, Ikunobu Muramatsu
Publikováno v:
Journal of Pharmacological Sciences, Vol 110, Iss 3, Pp 389-396 (2009)
Abstract.: [3H]-CGP12177 biphasically bound to β-adrenoceptors with high and low affinities in the segments and crude membranes of rabbit left ventricle. The low-affinity sites for [3H]-CGP12177 in the segments was double in density, compared to the
Externí odkaz:
https://doaj.org/article/572ea20b99f342c7bf41425dfb26404d
Autor:
Nolwenn Merlet, Nicolas Piriou, Bertrand Rozec, Amandine Grabherr, Benjamin Lauzier, Jean-Noël Trochu, Chantal Gauthier
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64711 (2013)
BACKGROUND: The toxicity of doxorubicin, leading to an irreversible heart failure, limits its use as chemotherapeutic agent. The beneficial effects of early administration of β-blocker were reported in patients with heart failure due to doxorubicin,
Externí odkaz:
https://doaj.org/article/f6b72633983649afb4cdde82dda7f3cf
Autor:
Thomas Dupas, Thomas Pelé, Justine Dhot, Mélanie Burban, Antoine Persello, Virginie Aillerie, Angélique Erraud, Angela Tesse, David Stevant, Angélique Blangy-Letheule, Céline Menguy, Vincent Sauzeau, Michel De Waard, Bertrand Rozec, Chantal Gauthier, Benjamin Lauzier
Publikováno v:
Oxidative medicine and cellular longevity. 2022
50% of patients with heart failure have a preserved ejection fraction (HFpEF). Numerous studies have investigated the pathophysiological mechanisms of HFpEF and have shown that endothelial dysfunction plays an important role in HFpEF. Yet no studies
Autor:
David, Roul, Bertrand, Rozec, Marine, Ferron, Mortéza, Erfanian, Antoine, Persello, Leslie, Audigane, Amandine, Grabherr, Angelique, Erraud, Nolwenn, Merlet, Damien, Guijarro, Ikunobu, Muramatsu, Benjamin, Lauzier, Chantal, Gauthier
Publikováno v:
Life sciences. 236
Endothelial dysfunction is one of the earliest symptoms in septic patients and plays an important role in the cardiovascular alterations. However, the endothelial mechanisms involved in the impaired sympathetic regulation of the cardiovascular system
Autor:
M. De Waard, E. Abgueguen, Chantal Gauthier, Angélique Erraud, A. Persello, P. Guedat, Bertrand Rozec, Benjamin Lauzier, P. Miniou, Virginie Aillerie
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 12:229
Background The systemic inflammation response syndrome (SIRS) is a consequence of the cardiopulmonary bypass (CPB) in cardiac surgery that can trigger multiple organ dysfunction (MOD). Pulmonary, renal and cerebral dysfunctions are the most common po
Autor:
Bertrand Rozec, A. Persello, Chantal Gauthier, P. Guedat, Benjamin Lauzier, P. Miniou, E. Abgueguen, Angélique Erraud, Virginie Aillerie, M. De Waard
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 11:219-220
Background The systemic inflammation response syndrome (SIRS) is a common side-effect of the cardiopulmonary bypass (CPB) in cardiac surgery. SIRS can trigger multiple organ dysfunction which can lead to patient death. Pulmonary dysfunction is the mo