Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Chantal Durette"'
Autor:
Leslie Hesnard, Catherine Thériault, Maxime Cahuzac, Chantal Durette, Krystel Vincent, Marie-Pierre Hardy, Joël Lanoix, Gabriel Ouellet Lavallée, Juliette Humeau, Pierre Thibault, Claude Perreault
Publikováno v:
Current Oncology, Vol 31, Iss 6, Pp 3099-3121 (2024)
Epithelial ovarian cancer (EOC) has not significantly benefited from advances in immunotherapy, mainly because of the lack of well-defined actionable antigen targets. Using proteogenomic analyses of primary EOC tumors, we previously identified 91 abe
Externí odkaz:
https://doaj.org/article/12eb4b94c81d4840bf379764f030a99c
Autor:
Jean-David Larouche, Céline M Laumont, Assya Trofimov, Krystel Vincent, Leslie Hesnard, Sylvie Brochu, Caroline Côté, Juliette F Humeau, Éric Bonneil, Joel Lanoix, Chantal Durette, Patrick Gendron, Jean-Philippe Laverdure, Ellen R Richie, Sébastien Lemieux, Pierre Thibault, Claude Perreault
Publikováno v:
eLife, Vol 12 (2024)
Transposable elements (TEs) are repetitive sequences representing ~45% of the human and mouse genomes and are highly expressed by medullary thymic epithelial cells (mTECs). In this study, we investigated the role of TEs on T-cell development in the t
Externí odkaz:
https://doaj.org/article/f8e5dc8f11474cf292db53bbc1880f9d
Autor:
Maria Virginia Ruiz Cuevas, Marie-Pierre Hardy, Jean-David Larouche, Anca Apavaloaei, Eralda Kina, Krystel Vincent, Patrick Gendron, Jean-Philippe Laverdure, Chantal Durette, Pierre Thibault, Sébastien Lemieux, Claude Perreault, Grégory Ehx
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-33 (2023)
Abstract MHC-I-associated peptides deriving from non-coding genomic regions and mutations can generate tumor-specific antigens, including neoantigens. Quantifying tumor-specific antigens’ RNA expression in malignant and benign tissues is critical f
Externí odkaz:
https://doaj.org/article/23d904d29bc341d1bcfd3983798d9305
Autor:
Jean-David Larouche, Assya Trofimov, Leslie Hesnard, Gregory Ehx, Qingchuan Zhao, Krystel Vincent, Chantal Durette, Patrick Gendron, Jean-Philippe Laverdure, Éric Bonneil, Caroline Côté, Sébastien Lemieux, Pierre Thibault, Claude Perreault
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-16 (2020)
Abstract Background Endogenous retroelements (EREs) constitute about 42% of the human genome and have been implicated in common human diseases such as autoimmunity and cancer. The dominant paradigm holds that EREs are expressed in embryonic stem cell
Externí odkaz:
https://doaj.org/article/d473cb8940d0454994221bb51e7f2e8e
Autor:
Maria Virginia Ruiz Cuevas, Marie-Pierre Hardy, Jaroslav Hollý, Éric Bonneil, Chantal Durette, Mathieu Courcelles, Joël Lanoix, Caroline Côté, Louis M. Staudt, Sébastien Lemieux, Pierre Thibault, Claude Perreault, Jonathan W. Yewdell
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108815- (2021)
Summary: Combining RNA sequencing, ribosome profiling, and mass spectrometry, we elucidate the contribution of non-canonical translation to the proteome and major histocompatibility complex (MHC) class I immunopeptidome. Remarkably, of 14,498 protein
Externí odkaz:
https://doaj.org/article/8429cc69806348e1a2f6b013296bbb36
Autor:
Céline M. Laumont, Tariq Daouda, Jean-Philippe Laverdure, Éric Bonneil, Olivier Caron-Lizotte, Marie-Pierre Hardy, Diana P. Granados, Chantal Durette, Sébastien Lemieux, Pierre Thibault, Claude Perreault
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Cryptic translation of the 'non-coding' genome is increasingly recognised, however its biological significance remains unclear. Laumont et al.employ proteogenomic techniques to map the human immunoproteome, and find that approximately 10% of MHC clas
Externí odkaz:
https://doaj.org/article/8e030826a1744d55a142f5a4d3124d1e
Autor:
Venkatesh Kota, Gunhild Sommer, Chantal Durette, Pierre Thibault, Erna A van Niekerk, Jeffery L Twiss, Tilman Heise
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156365 (2016)
The RNA-binding protein La is involved in several aspects of RNA metabolism including the translational regulation of mRNAs and processing of pre-tRNAs. Besides its well-described phosphorylation by Casein kinase 2, the La protein is also posttransla
Externí odkaz:
https://doaj.org/article/69539dd566674c2b92c297fa8321867f
Autor:
Claude Perreault, Pierre Thibault, Pamela S. Ohashi, Douglas G. Millar, Sébastien Lemieux, Mathieu Courcelles, Krystel Vincent, Patrick Gendron, Céline M. Laumont, Éric Bonneil, Caroline Côté, Chantal Durette, Joël Lanoix, Jean-Philippe Laverdure, Qingchuan Zhao
Table S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25ed94e4467b7ba35fea55b4a5057116
https://doi.org/10.1158/2326-6066.22542735.v1
https://doi.org/10.1158/2326-6066.22542735.v1
Autor:
Claude Perreault, Pierre Thibault, Pamela S. Ohashi, Douglas G. Millar, Sébastien Lemieux, Mathieu Courcelles, Krystel Vincent, Patrick Gendron, Céline M. Laumont, Éric Bonneil, Caroline Côté, Chantal Durette, Joël Lanoix, Jean-Philippe Laverdure, Qingchuan Zhao
High-grade serous ovarian cancer (HGSC), the principal cause of death from gynecologic malignancies in the world, has not significantly benefited from advances in cancer immunotherapy. Although HGSC infiltration by lymphocytes correlates with superio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780275a8dc523ffe4f4ff08a1f9583db
https://doi.org/10.1158/2326-6066.c.6550029
https://doi.org/10.1158/2326-6066.c.6550029
Autor:
Claude Perreault, Pierre Thibault, Pamela S. Ohashi, Douglas G. Millar, Sébastien Lemieux, Mathieu Courcelles, Krystel Vincent, Patrick Gendron, Céline M. Laumont, Éric Bonneil, Caroline Côté, Chantal Durette, Joël Lanoix, Jean-Philippe Laverdure, Qingchuan Zhao
Supplementary figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112db95cc7c677f617565aa2c169e403
https://doi.org/10.1158/2326-6066.22542747.v1
https://doi.org/10.1158/2326-6066.22542747.v1