GnRH regulates the expression of its receptor accessory protein SET in pituitary gonadotropes.

Autor: Charlotte Avet, Chantal Denoyelle, David L'Hôte, Florence Petit, Céline J Guigon, Joëlle Cohen-Tannoudji, Violaine Simon

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0201494 (2018)

Reproductive function is under the control of the neurohormone GnRH, which activates a G-protein-coupled receptor (GnRHR) expressed in pituitary gonadotrope cells. GnRHR activates a complex signaling network to regulate synthesis and secretion of the

Externí odkaz: https://doaj.org/article/46afed9c6b2b4304835cba11b7afbfe2

L’hormone anti-müllérienne : un nouveau régulateur des cellules gonadotropes hypophysaires

Autor: Céline J. Guigon, Chantal Denoyelle, Nathalie di Clemente, Chrystèle Racine, David L'Hôte, Joëlle Cohen-Tannoudji, Ghislaine Garrel

Publikováno v: médecine/sciences. 32:1076-1078

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac9c773ad2ac00fe1f68cb2e50ce6bd5
https://doi.org/10.1051/medsci/20163212010

Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway

Autor: Valérie Grange-Messent, Julien Dairou, Jean-Marie Dupret, Violaine Simon, Chantal Denoyelle, Richard Wargnier, Alice Pierre, Joëlle Cohen-Tannoudji, Charlotte Avet

Publikováno v: Endocrinology
Endocrinology, Oxford University Press, 2017, 158 (10), pp.3200-3211. ⟨10.1210/en.2017-00374⟩

Secretion of 17-β-estradiol (E2) by human granulosa cells can be disrupted by various environmental toxicants. In the current study, we investigated whether carbon black nanoparticles (CB NPs) affect the steroidogenic activity of cultured human gran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91aecc8ef2f87cb8929ba443550a94e
https://pubmed.ncbi.nlm.nih.gov/28977593

AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs

Autor: Marc Foretz, Bertrand Friguet, Mustapha Rouis, Chantal Denoyelle, Michel Raymondjean, Benoit Viollet, Lucas Ravaux, Khadija El Hadri

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2015, 10 (7), pp.e0132498. ⟨10.1371/journal.pone.0132498⟩
PLoS ONE, Vol 10, Iss 7, p e0132498 (2015)
PLoS ONE, Public Library of Science, 2015, 10 (7), pp.e0132498. 〈10.1371/journal.pone.0132498〉
PLoS ONE, 2015, 10 (7), pp.e0132498. ⟨10.1371/journal.pone.0132498⟩

International audience; Secretory Phospholipase A2 of type IIA (sPLA2 IIA) plays a crucial role in the production of lipid mediators by amplifying the neointimal inflammatory context of the vascular smooth muscle cells (VSMCs), especially during athe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93eecbf626d3279e19f55c8e23736df
https://hal.sorbonne-universite.fr/hal-01233095/document

Unsaturated fatty acids disrupt Smad signaling in gonadotrope cells leading to inhibition of FSHβ gene expression

Autor: Julien Dairou, Violaine Simon, Chantal Denoyelle, Muhammad Ishaq, Stéphanie Migrenne, Joëlle Cohen-Tannoudji, Ghislaine Garrel, Christophe Magnan, Céline Cruciani-Guglielmacci, Claude Rouch

Publikováno v: Endocrinology. 155(2)

Reproductive function is highly dependent on nutritional input. We recently provided evidence that the unsaturated ω6 fatty acid (FA), linoleic acid (linoleic), interferes with transcription and secretion of the gonadotropin LH, highlighting the exi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3914e01cdd188da5b9f5ec6360562b98
https://pubmed.ncbi.nlm.nih.gov/24248462