Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Chantal Chudoba"'
Autor:
Kristina Wardelmann, Sabine Blümel, Michaela Rath, Eugenia Alfine, Chantal Chudoba, Mareike Schell, Weikang Cai, Robert Hauffe, Kathrin Warnke, Tanina Flore, Katrin Ritter, Jürgen Weiß, C. Ronald Kahn, André Kleinridders
Publikováno v:
Molecular Metabolism, Vol 21, Iss , Pp 68-81 (2019)
Objective: Insulin action in the brain controls metabolism and brain function, which is linked to proper mitochondrial function. Conversely, brain insulin resistance associates with mitochondrial stress and metabolic and neurodegenerative diseases. I
Externí odkaz:
https://doaj.org/article/7c9d14609d4c4b8591384c45fafcc306
Autor:
Mareike Schell, Chantal Chudoba, Antoine Leboucher, Eugenia Alfine, Tanina Flore, Katrin Ritter, Katharina Weiper, Andreas Wernitz, Janin Henkel, André Kleinridders
Publikováno v:
Nutrients, Vol 12, Iss 5, p 1518 (2020)
Overconsumption of high-fat and cholesterol-containing diets is detrimental for metabolism and mitochondrial function, causes inflammatory responses and impairs insulin action in peripheral tissues. Dietary fatty acids can enter the brain to mediate
Externí odkaz:
https://doaj.org/article/e6b96d0596f74683b775fcda5e3dc680
Autor:
Robert Hauffe, C. Ronald Kahn, Eugenia Alfine, Jürgen Weiß, Tanina Flore, Kathrin Warnke, Michaela Rath, Chantal Chudoba, Mareike Schell, Weikang Cai, Sabine Blümel, Kristina Wardelmann, Katrin Ritter, André Kleinridders
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 21, Iss, Pp 68-81 (2019)
Molecular Metabolism, Vol 21, Iss, Pp 68-81 (2019)
Objective Insulin action in the brain controls metabolism and brain function, which is linked to proper mitochondrial function. Conversely, brain insulin resistance associates with mitochondrial stress and metabolic and neurodegenerative diseases. In
Autor:
Katrin Ritter, Michaela Rath, Anna P. Kipp, André Kleinridders, Stefanie Deubel, Vanessa Stein, Tanina Flore, Mareike Schell, Kristina Wardelmann, Johannes F. Kopp, Kai Kappert, Chantal Chudoba, Robert Hauffe, Matthias Blüher, Maria Luiza Schwarz, Tanja Schwerdtle
Publikováno v:
JCI insight, 5(11):e136283
JCI Insight
JCI Insight
Insulin receptor signaling is crucial for white adipose tissue (WAT) function. Consequently, lack of insulin receptor (IR) in WAT results in a diabetes-like phenotype. Yet, causes for IR downregulation in WAT of patients with diabetes are not well un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b20cef75a5033321a0310948baad975
https://repository.publisso.de/resource/frl:6426621
https://repository.publisso.de/resource/frl:6426621
Autor:
André Kleinridders, Chantal Chudoba
Publikováno v:
Diabetes. 68
Brain insulin action regulates metabolism and behavior. Conversely in diabetes, brain insulin resistance associates with obesity and behavioral abnormalities. Intranasal insulin (INI) treatment activates brain insulin signaling in rodents and humans
Publikováno v:
Biological chemistry.
The prevalence of obesity and its co-morbidities such as insulin resistance and type 2 diabetes are tightly linked to increased ingestion of palatable fat enriched food. Thus, it seems intuitive that the brain senses elevated amounts of fatty acids (