Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Chantal Beauchemin"'
Autor:
Dan Sexton, Ryan Faucette, Melody Rivera-Hernandez, Jon A. Kenniston, Nikolaos Papaioannou, Janja Cosic, Kris Kopacz, Gary Salmon, Chantal Beauchemin, Salomé Juethner, Dave Yeung
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
BackgroundCleaved high-molecular-weight kininogen (HKa) is a disease state biomarker of kallikrein-kinin system (KKS) activation in patients with hereditary angioedema due to C1 inhibitor deficiency (HAE-C1INH), the endogenous inhibitor of plasma kal
Externí odkaz:
https://doaj.org/article/0d761743922e42949564199f1786651f
Autor:
Aline C Habison, Marta Pires de Miranda, Chantal Beauchemin, Min Tan, Sofia A Cerqueira, Bruno Correia, Rajesh Ponnusamy, Edward J Usherwood, Colin E McVey, J Pedro Simas, Kenneth M Kaye
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006555 (2017)
Many pathogens, including Kaposi's sarcoma herpesvirus (KSHV), lack tractable small animal models. KSHV persists as a multi-copy, nuclear episome in latently infected cells. KSHV latency-associated nuclear antigen (kLANA) binds viral terminal repeat
Externí odkaz:
https://doaj.org/article/7c5642703ce84bb681186f9a7a5ad271
Autor:
Bruno Correia, Sofia A Cerqueira, Chantal Beauchemin, Marta Pires de Miranda, Shijun Li, Rajesh Ponnusamy, Lénia Rodrigues, Thomas R Schneider, Maria A Carrondo, Kenneth M Kaye, J Pedro Simas, Colin E McVey
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003673 (2013)
Latency-associated nuclear antigen (LANA) mediates γ2-herpesvirus genome persistence and regulates transcription. We describe the crystal structure of the murine gammaherpesvirus-68 LANA C-terminal domain at 2.2 Å resolution. The structure reveals
Externí odkaz:
https://doaj.org/article/e9ab2330f422454c8330e6d4aa52cb19
Autor:
Colin E. McVey, Sofia A. Cerqueira, Bruno Correia, Rajesh Ponnusamy, Chantal Beauchemin, Edward J. Usherwood, J. Pedro Simas, Min Tan, Aline C. Habison, Marta Pires de Miranda, Kenneth M. Kaye
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006555 (2017)
PLoS Pathogens
PLoS Pathogens
Copyright: © 2017 Habison et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d27bd468347cd2bf5ab5d4b1e4f32d6
https://hdl.handle.net/10451/54372
https://hdl.handle.net/10451/54372
Publikováno v:
SLAS Discovery. 19:947-958
Kaposi's sarcoma-associated herpesvirus (KSHV) has a causative role in several human malignancies, especially in immunocompromised hosts. KSHV latently infects tumor cells and persists as an extrachromosomal episome (plasmid). KSHV latency-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bebe4201b389af0d118609976d57d8
https://doi.org/10.1177/1087057114520973
https://doi.org/10.1177/1087057114520973
Autor:
Alessandro Tocchio, Utkan Demirci, Alyssa Holman, Thiruppathiraja Chinnasamy, Sebnem Unluisler, Srikar Srivatsa, Pu Chen, Franceline Juillard, Chantal Beauchemin, Umut A. Gurkan, Serli Canikyan, Rami El Assal, Kenneth M. Kaye
Publikováno v:
Scientific Reports
Cancer cells have been increasingly grown in pharmaceutical research to understand tumorigenesis and develop new therapeutic drugs. Currently, cells are typically grown using two-dimensional (2-D) cell culture approaches, where the native tumor micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad00009d258813e343b04fa5b115321
https://doi.org/10.1038/srep39144
https://doi.org/10.1038/srep39144
Publikováno v:
Journal of Virology
Murine gammaherpesvirus 68 (MHV68) ORF73 (mLANA) has sequence homology to Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA). LANA acts on the KSHV terminal repeat (TR) elements to mediate KSHV episome maintenanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f65c73c1d55e9d46923f569e2c96c75
https://doi.org/10.1128/jvi.01656-12
https://doi.org/10.1128/jvi.01656-12
Publikováno v:
Journal of Virology. 81:10905-10913
Poly(A) binding protein 2 (PABP2) of Arabidopsis thaliana was previously shown to interact with VPg-Pro of turnip mosaic virus (TuMV) and may consequently play an important role during infection. Subcellular fractionation experiments revealed that PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c617b7b0db54840328ae0d68b37b9d
https://doi.org/10.1128/jvi.01243-07
https://doi.org/10.1128/jvi.01243-07
Publikováno v:
Transgenic Research. 16:213-222
We developed an inactivated DNA replicon of Turnip Mosaic Virus (TuMV), which was reactivated by a recombination event based on the Cre-loxP system. Viral replication was prevented by the insertion of a translation terminator sequence flanked by two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6feb7afb0be331be73f65960866bf133
https://doi.org/10.1007/s11248-006-9038-y
https://doi.org/10.1007/s11248-006-9038-y
Autor:
Bruno, Correia, Sofia A, Cerqueira, Chantal, Beauchemin, Marta, Pires de Miranda, Shijun, Li, Rajesh, Ponnusamy, Lénia, Rodrigues, Thomas R, Schneider, Maria A, Carrondo, Kenneth M, Kaye, J Pedro, Simas, Colin E, McVey
Publikováno v:
PLoS Pathogens
Latency-associated nuclear antigen (LANA) mediates γ2-herpesvirus genome persistence and regulates transcription. We describe the crystal structure of the murine gammaherpesvirus-68 LANA C-terminal domain at 2.2 Å resolution. The structure reveals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbc112eeda7cae9a212863e79abcaf2a
https://pubmed.ncbi.nlm.nih.gov/24146618
https://pubmed.ncbi.nlm.nih.gov/24146618