Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Chantal Baron"'
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4116 (2009)
BACKGROUND: Injection of CD8 T cells primed against immunodominant minor histocompatibility antigens (MiHA) such as H7(a) can eradicate leukemia and solid tumors. To understand why MiHA-targeted T cells have such a potent antitumor effect it is essen
Externí odkaz:
https://doaj.org/article/527a6446a38b4392a10d5168df6c5f0b
Autor:
Chantal Baron, Roland Somogyi, Larry D Greller, Vincent Rineau, Peter Wilkinson, Carolyn R Cho, Mark J Cameron, David J Kelvin, Pierre Chagnon, Denis-Claude Roy, Lambert Busque, Rafick-Pierre Sékaly, Claude Perreault
Publikováno v:
PLoS Medicine, Vol 4, Iss 1, p e23 (2007)
BackgroundGraft-versus-host disease (GVHD) results from recognition of host antigens by donor T cells following allogeneic hematopoietic cell transplantation (AHCT). Notably, histoincompatibility between donor and recipient is necessary but not suffi
Externí odkaz:
https://doaj.org/article/ba423f1c55f54622836516f885b18bda
Autor:
Chantal Baron, Samer Mansour, Denis-Claude Roy, Reda Salem, Louis-Mathieu Stevens, Nicolas Noiseux, Daiana Masckauchan, Jessica Forcillo, Eric Larose, Ignacio Prieto
Publikováno v:
Canadian Journal of Cardiology. 29:441-447
Background The Imp lantation of A utologous C D133 + S t em Cells in Patients Undergoing CABG (IMPACT-CABG) trial is investigating the feasibility, safety, and efficacy of intramyocardial injections of autologous CD133 + stem cells during coronary ar
Autor:
Claude Perreault, Richard LeBlanc, Mark J. Cameron, Chantal Baron, Marie-Christine Meunier, Etienne Caron, Caroline Côté, David J. Kelvin, Vincent Rineau
Publikováno v:
The Journal of Immunology. 177:8466-8475
Restriction of T cell responses to a few epitopes (immunodominance) is a central feature of immune responses. We analyzed the entire transcriptome of effector CD8 T cells specific for a dominant (H7a) and a cryptic (HY) mouse Ag and performed a longi
Autor:
Vincent Rineau, Jean-Sébastien Delisle, Julie Bergeron, Marie-Christine Meunier, Chantal Baron, Claude Perreault
Publikováno v:
Nature Medicine. 11:1222-1229
T cells responsive to minor histocompatibility (H) antigens are extremely effective in curing leukemia but it remains unknown whether they can eradicate solid tumors. We report that injection of CD8(+) T cells primed against the immunodominant H7(a)
Publikováno v:
Biology of Blood and Marrow Transplantation. 11(4):260-271
When presented alone, H7a and HY antigens elicit CD8 T-cell responses of similar amplitude, but H7a totally abrogates the response to HY when both antigens are presented on the same antigen-presenting cell. We found that H7a- and HY-specific T-cell p
Autor:
Kevin Mcbride, Serge Picard, Alexander W. Bell, Chantal Baron, John J.M. Bergeron, Stéphanie Martin, Claude Perreault, Daniel Boismenu
Publikováno v:
Immunogenetics. 54:562-569
The B6(dom1) minor histocompatibility antigen (MiHA) is a model antigen, since it is both the epitome of an immunodominant epitope and an ideal target for adoptive cancer immunotherapy. Based on DNA sequencing and MS/MS analyses, we report that B6(do
Autor:
Denis-Claude Roy, Pierre Fontaine, Claude Perreault, Laurent Knafo, Chantal Baron, Guillaume Roy-Proulx
Publikováno v:
Nature Medicine. 7:789-794
Adoptive transfer of T cells reactive to minor histocompatibility antigens has the unmatched ability to eradicate malignant hematopoietic cells. Unfortunately, its use is hampered by the associated graft-versus-host disease. The critical issue of a p
Autor:
Denis-Claude Roy, Lambert Busque, Bonny Y, Johanne Mattioli, Claude Perreault, Martin Guimond, Robert Bélanger, Chantal Baron
Publikováno v:
British Journal of Haematology. 109:130-137
Donor lymphocyte infusions are particularly effective for remission induction in malignant cells in patients who relapse after allogeneic progenitor cell transplantation (PCT) and who remain sensitive to the administration of unprimed donor T and/or
Publikováno v:
British Journal of Pharmacology. 127:969-979
1. The potent coronary vasoconstrictor, endothelin-1 (ET-1) may also regulate neutrophil traffic into tissues. The aim of the present study was to characterize the endothelin receptors responsible and to investigate the underlying mechanisms. 2. ET-1