Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chantal, Kwizera"'
Autor:
Lara Garcia-Varela, Khaled Attia, John Carlo Sembrano, Olivier Jacquet, Inês F. Antunes, Chantal Kwizera, Ton J. Visser, Rudi A. J. O. Dierckx, Philip H. Elsinga, Gert Luurtsema
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract Background [18F]MC225 is a radiotracer for imaging P-glycoprotein (P-gp) function at the blood-brain barrier. The P-gp function can be altered due to different factors, for instance, decreased P-gp function has been described in patients wit
Externí odkaz:
https://doaj.org/article/f11bc4b286374a8baf776605013c3d42
Autor:
Rudi Dierckx, Lara García-Varela, Ton J. Visser, Khaled A. Attia, Chantal Kwizera, Gert Luurtsema, John Carlo Sembrano, Inês Antunes, Olivier Jacquet, Philip H. Elsinga
Publikováno v:
EJNMMI Radiopharmacy and Chemistry
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-13 (2021)
EJNMMI Radiopharmacy and Chemistry, 6(1), 1-13. Springer
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-13 (2021)
EJNMMI Radiopharmacy and Chemistry, 6(1), 1-13. Springer
Background [18F]MC225 is a radiotracer for imaging P-glycoprotein (P-gp) function at the blood-brain barrier. The P-gp function can be altered due to different factors, for instance, decreased P-gp function has been described in patients with Alzheim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9b1b344c6173c1407265ac7d6d8cc1
https://doi.org/10.21203/rs.3.rs-377973/v1
https://doi.org/10.21203/rs.3.rs-377973/v1
Autor:
David Vállez García, M. C. Houwertjes, Philip H. Elsinga, Xiaoyun Zhou, Jurgen W. A. Sijbesma, Chantal Kwizera, Rudi Dierckx, Riemer H. J. A. Slart, Janine Doorduin, Bram Maas, Peter Meerlo, Aren van Waarde
Publikováno v:
Molecular Imaging and Biology
Sijbesma, J W A, Zhou, X, Vállez García, D, Houwertjes, M C, Doorduin, J, Kwizera, C, Maas, B, Meerlo, P, Dierckx, R A, Slart, R H J A, Elsinga, P H & van Waarde, A 2016, ' Novel Approach to Repeated Arterial Blood Sampling in Small Animal PET : Application in a Test-Retest Study with the Adenosine A1 Receptor Ligand [ 11 C]MPDX ', Molecular Imaging and Biology, vol. 18, no. 5, pp. 715-723 . https://doi.org/10.1007/s11307-016-0954-9
Molecular Imaging and Biology, 18(5), 715-723. SPRINGER
Molecular Imaging and Biology, 18(5), 715-723. Springer New York
Sijbesma, J W A, Zhou, X, Vállez García, D, Houwertjes, M C, Doorduin, J, Kwizera, C, Maas, B, Meerlo, P, Dierckx, R A, Slart, R H J A, Elsinga, P H & van Waarde, A 2016, ' Novel Approach to Repeated Arterial Blood Sampling in Small Animal PET : Application in a Test-Retest Study with the Adenosine A1 Receptor Ligand [ 11 C]MPDX ', Molecular Imaging and Biology, vol. 18, no. 5, pp. 715-723 . https://doi.org/10.1007/s11307-016-0954-9
Molecular Imaging and Biology, 18(5), 715-723. SPRINGER
Molecular Imaging and Biology, 18(5), 715-723. Springer New York
Purpose: Small animal positron emission tomography (PET) can be used to detect small changes in neuroreceptor availability. This often requires rapid arterial blood sampling. However, current catheterization procedures do not allow repeated blood sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09c4933db631f70d7b50423b4cfa620
https://hdl.handle.net/11370/403c8c28-c311-44a8-b5bb-09752f98f1fd
https://hdl.handle.net/11370/403c8c28-c311-44a8-b5bb-09752f98f1fd
Autor:
Kiichi Ishiwata, Chantal Kwizera, Csaba Nyakas, Nisha K. Ramakrishnan, Aren van Waarde, Rudi Dierckx, Jurgen W. A. Sijbesma, Anniek K. D. Visser, Anna A. Rybczynska, Paul G.M. Luiten, Philip H. Elsinga
Publikováno v:
Molecular Imaging and Biology
Molecular Imaging and Biology, 18(4), 588-597. SPRINGER
Molecular Imaging and Biology, 18(4), 588-597. SPRINGER
Purpose Sigma-1 receptor ligands modulate the release of several neurotransmitters and intracellular calcium signaling. We examined the binding of a radiolabeled sigma-1 agonist in the aging rat brain with positron emission tomography (PET). Procedur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8afab9f5729de974cfdf1e5d79ea8ea
https://doi.org/10.1007/s11307-015-0917-6
https://doi.org/10.1007/s11307-015-0917-6
Autor:
Kristoffer Sahlholm, Nisha Kuzhuppilly Ramakrishnan, Aren van Waarde, Jurgen W. A. Sijbesma, Philip H. Elsinga, Bram Maas, Daniel Marcellino, Rudi Dierckx, Chantal Kwizera
Publikováno v:
Psychopharmacology, 232(18), 3443-3453. SPRINGER
Psychopharmacology
Psychopharmacology
Rationale Dopamine stabilizers have stimulatory actions under low dopamine tone and inhibitory actions under high dopamine tone without eliciting catalepsy. These compounds are dopamine D2 receptor (D2R) antagonists or weak partial agonists and may h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e32ad941d8ee3196522032929f3525d
https://research.rug.nl/en/publications/280319d1-6a84-4485-bcf0-6a8ba3f7924a
https://research.rug.nl/en/publications/280319d1-6a84-4485-bcf0-6a8ba3f7924a
Autor:
Csaba Nyakas, Philip H. Elsinga, Paul G.M. Luiten, Aren van Waarde, Kiichi Ishiwata, Krisztina Marosi, Nisha Kuzhuppilly Ramakrishnan, Chantal Kwizera, Rudi Dierckx
Publikováno v:
Molecular Imaging and Biology, 17(2), 231-238. SPRINGER
PURPOSE: Sigma-1 receptors are involved in learning and memory processes. We assessed sigma-1 receptor expression and memory function in two animal models of cognitive impairment.PROCEDURES: Male Wistar-Hannover rats were either lesioned by unilatera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfec7d43c390e6f53587c40eb40bcf9
https://doi.org/10.1007/s11307-014-0780-x
https://doi.org/10.1007/s11307-014-0780-x
Autor:
Jan Pruim, Rudi Dierckx, Anna A. Rybczynska, Jurgen W. A. Sijbesma, Chantal Kwizera, Krisztina Marosi, Philip H. Elsinga, Csaba Nyakas, Aren van Waarde, Anniek K. D. Visser, Kiichi Ishiwata, Nisha Kuzhuppilly Ramakrishnan
Publikováno v:
Journal of Nuclear Medicine, 54(8), 1377-1383. SOC NUCLEAR MEDICINE INC
Pituitary tumors are often detected only after death or at late stages of the disease when they are macroadenomas with a low surgical cure rate. Spontaneous pituitary tumors occur in rats over 1 y of age. In an ongoing study of changes in sigma-1 ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5606a3bac8c51f8c2d6333fd0c2c88
https://doi.org/10.2967/jnumed.112.115931
https://doi.org/10.2967/jnumed.112.115931
Autor:
Enza, Lacivita, Ermelinda, Lucente, Chantal, Kwizera, Ines F, Antunes, Mauro, Niso, Paola, De Giorgio, Roberto, Perrone, Nicola A, Colabufo, Philip H, Elsinga, Marcello, Leopoldo
Publikováno v:
Bioorganicmedicinal chemistry. 25(1)
Gastrin-releasing peptide receptors (GRP-Rs, also known as bombesin 2 receptors) are overexpressed in a variety of human cancers, including prostate cancer, and therefore they represent a promising target for in vivo imaging of tumors using positron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::170fcf3ccb1d51a6b2a22606474efe6f
https://pubmed.ncbi.nlm.nih.gov/27863916
https://pubmed.ncbi.nlm.nih.gov/27863916
Autor:
V. Pilla Reddy, Rudi Dierckx, van Aren Waarde, K. Ishiwata, Philippus Elsinga, Jurgen W. A. Sijbesma, Johannes H. Proost, Csaba Nyakas, Nisha Kuzhuppilly Ramakrishnan, Chantal Kwizera
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 39:155-303
Cutamesine (SA4503) is a selective sigma-1 receptor agonist, currently in Phase II clinical trials for depression and post stroke neurological disturbances. Cutamesine has been found to be effective in several rodent models of amnesia and depression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b2c3ee98ef7b60a0fdd134f4a90957
https://doi.org/10.1007/s00259-012-2221-x
https://doi.org/10.1007/s00259-012-2221-x
Autor:
Nisha Kuzhuppilly Ramakrishnan, Aren van Waarde, Francesco Berardi, Mariangela Cantore, Anna A. Rybczynska, Roberto Perrone, Chantal Kwizera, Rudi Dierckx, Philip H. Elsinga, Nicola Antonio Colabufo, Jurgen W. A. Sijbesma, Johan R. de Jong
Publikováno v:
Journal of Medicinal Chemistry, 52(14), 4524-4532. AMER CHEMICAL SOC
P-glycoprotein (P-gp) is an ATP-dependent efflux pump protecting the body against xenobiotics. A P-gp substrate (7) and an inhibitor (6) were labeled with (11)C, resulting in potential tracers of P-gp function and expression. Methods: 6 and 7 were la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85343a6567686d278bc5a83583c6263
https://research.rug.nl/en/publications/e673ae89-3825-478a-8e92-19f15e686c6a
https://research.rug.nl/en/publications/e673ae89-3825-478a-8e92-19f15e686c6a