Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Chantal, Csajka"'
Autor:
Yann Thoma, Annie E Cathignol, Yuan J Pétermann, Margaretha L Sariko, Bibie Said, Chantal Csajka, Monia Guidi, Stellah G Mpagama
Publikováno v:
JMIR Research Protocols, Vol 13, p e58720 (2024)
BackgroundThe end tuberculosis (TB) strategy requires a novel patient treatment approach contrary to the one-size-fits-all model. It is well known that each patient’s physiology is different and leads to various rates of drug elimination. Therapeut
Externí odkaz:
https://doaj.org/article/6abcebaf4e39496f8758faf47eba9e28
Autor:
Jean Terrier, Frédéric Gaspar, Pauline Gosselin, Olivier Raboud, Camille Lenoir, Victoria Rollason, Chantal Csajka, Caroline Samer, Pierre Fontana, Youssef Daali, Jean‐Luc Reny, for the OptimAT study group
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 12, Pp 1872-1883 (2023)
Abstract When used in real‐world conditions, substantial interindividual variations in direct oral anticoagulant (DOAC) plasma concentrations are observed for a given dose, leading to a risk of over‐ or under‐exposure and clinically significant
Externí odkaz:
https://doaj.org/article/1a99f15a9a8e4eef9631ce2e055ca3a6
Autor:
Verena Gotta, Julia Anna Bielicki, Paolo Paioni, Chantal Csajka, Dominic Stefan Bräm, Christoph Berger, Elisabeth Giger, Michael Buettcher, Klara M. Posfay-Barbe, John van den Anker, Marc Pfister
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 4 (2024)
BACKGROUND AND AIMS: Pharmacometric in silico approaches are frequently applied to guide decisions concerning dosage regimes during the development of new medicines. We aimed to demonstrate how such pharmacometric modelling and simulation can provide
Externí odkaz:
https://doaj.org/article/1e2536a16ca447fea78a789062ead18b
Autor:
Claire Coumau, Frederic Gaspar, Jean Terrier, Angela Schulthess-Lisibach, Monika Lutters, Marie-Annick Le Pogam, Chantal Csajka
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Toxicity or treatment failure related to drug-drug interactions (DDIs) are known to significantly affect morbidity and hospitalization rates. Despite the availability of numerous databases for DDIs identification and management, their inf
Externí odkaz:
https://doaj.org/article/1c60891baf2e4fc6b4d1b63ac225f268
Autor:
Frédéric Gaspar, Jean Terrier, Samantha Favre, Pauline Gosselin, Pierre Fontana, Youssef Daali, Camille Lenoir, Caroline Flora Samer, Victoria Rollason, Jean‐Luc Reny, Chantal Csajka, Monia Guidi
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 10, Pp 1541-1552 (2023)
Abstract This study aimed to characterize apixaban pharmacokinetics (PKs) and its variability in a real‐world clinical setting of hospitalized patients using a population PK (PopPK) approach. Model‐based simulations helped to identify factors tha
Externí odkaz:
https://doaj.org/article/12bfdd438de34a6eaf7cee9749ed2cb1
Autor:
Perrine Courlet, Daniel Abler, Monia Guidi, Pascal Girard, Federico Amato, Naik Vietti Violi, Matthieu Dietz, Nicolas Guignard, Alexandre Wicky, Sofiya Latifyan, Rita De Micheli, Mario Jreige, Clarisse Dromain, Chantal Csajka, John O. Prior, Karthik Venkatakrishnan, Olivier Michielin, Michel A. Cuendet, Nadia Terranova
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 8, Pp 1170-1181 (2023)
Abstract The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer therapy but only a fraction of patients benefits from this therapy. Model‐informed drug development can be used to assess prognostic and predictive clinical f
Externí odkaz:
https://doaj.org/article/8022c02f0e224911a18a052e668f5e9a
Autor:
Anaëlle Monfort, Evelina Cardoso, Chin B. Eap, Céline J. Fischer Fumeaux, Myriam Bickle Graz, Mathilde Morisod Harari, Etienne Weisskopf, Peggy Gandia, Karel Allegaert, Hedvig Nordeng, Jean-Michel Hascoët, Olivier Claris, Manuella Epiney, Chantal Csajka, Monia Guidi, Ema Ferreira, Alice Panchaud
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionFluvoxamine is widely used to treat depression during pregnancy and lactation. However, limited data are available on its transfer to the fetus or in human milk. This case series provides additional information on the infant exposure to f
Externí odkaz:
https://doaj.org/article/9f9c1db79b0247a78d95dda076c41324
Autor:
Andrea Brioschi Guevara, Melanie Bieler, Daniele Altomare, Marcelo Berthier, Chantal Csajka, Sophie Dautricourt, Jean-François Démonet, Alessandra Dodich, Giovanni B. Frisoni, Carlo Miniussi, José Luis Molinuevo, Federica Ribaldi, Philip Scheltens, Gael Chételat
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Cognitive complaints in the absence of objective cognitive impairment, observed in patients with subjective cognitive decline (SCD), are common in old age. The first step to postpone cognitive decline is to use techniques known to improve co
Externí odkaz:
https://doaj.org/article/d51c674f98664552a6c8f8fd130d5969
Autor:
Frederic Gaspar, Monika Lutters, Patrick Emanuel Beeler, Pierre Olivier Lang, Bernard Burnand, Fabio Rinaldi, Christian Lovis, Chantal Csajka, Marie-Annick Le Pogam
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 11, p e40456 (2022)
BackgroundOne-third of older inpatients experience adverse drug events (ADEs), which increase their mortality, morbidity, and health care use and costs. In particular, antithrombotic drugs are among the most at-risk medications for this population. R
Externí odkaz:
https://doaj.org/article/2092b630904a42268d50fec77e89ec24
Autor:
Georgia Mitropoulou, Angela Koutsokera, Chantal Csajka, Sylvain Blanchon, Alain Sauty, Jean-Francois Brunet, Christophe von Garnier, Grégory Resch, Benoit Guery
Publikováno v:
European Respiratory Review, Vol 31, Iss 166 (2022)
Lower respiratory tract infections lead to significant morbidity and mortality. They are increasingly caused by multidrug-resistant pathogens, notably in individuals with cystic fibrosis, hospital-acquired pneumonia and lung transplantation. The use
Externí odkaz:
https://doaj.org/article/de2e561e43614de5a9f439481863ab50