Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Chantal, Allamargot"'
Publikováno v:
Kidney360. 4:162-176
Autor:
Jiliang Xia, Hongwei Xu, Xiaoyan Zhang, Chantal Allamargot, Kristen L. Coleman, Randy Nessler, Ivana Frech, Guido Tricot, Fenghuang Zhan
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 41-49 (2017)
High-dose chemotherapies to treat multiple myeloma (MM) can be life-threatening due to toxicities to normal cells and there is a need to target only tumor cells and/or lower standard drug dosage without losing efficacy. We show that pharmacologically
Externí odkaz:
https://doaj.org/article/e916b68488b5402aa134edaabcd08728
Diabetic nephropathy (DN) is characterized by increased endocytosis and degradation of nephrin, a protein that comprises the molecular sieve of the glomerular filtration barrier, but the key trafficking mechanism that connects the initial endocytic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9960c6c7b9e0660e5b6b8d8e9e9c4ab
https://doi.org/10.1101/2022.10.01.510475
https://doi.org/10.1101/2022.10.01.510475
Autor:
Shubha Murthy, Olha M Koval, Juan M Ramiro Diaz, Santosh Kumar, Daniel Nuno, Jason A Scott, Chantal Allamargot, Linda J Zhu, Kim Broadhurst, Velarchana Santhana, William J Kutschke, Kaikobad Irani, Kathryn G Lamping, Isabella M Grumbach
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186311 (2017)
The multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine kinase important in transducing intracellular Ca2+ signals. While in vitro data regarding the role of CaMKII in the regulation of endothelial nitric oxide
Externí odkaz:
https://doaj.org/article/f354a460347249199e1fb8733db21214
Autor:
Sudhanshu P Raikwar, Eun-Mi Kim, William I Sivitz, Chantal Allamargot, Daniel R Thedens, Nicholas Zavazava
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116582 (2015)
Type 1 diabetes (T1D) is caused by autoimmune disease that leads to the destruction of pancreatic β-cells. Transplantation of cadaveric pancreatic organs or pancreatic islets can restore normal physiology. However, there is a chronic shortage of cad
Externí odkaz:
https://doaj.org/article/312804c105e143baa5f66b37b6c86853
Autor:
Jacob Sharafuddin, E. Dale Abel, Kathy Zimmerman, Long-Sheng Song, Greg V Collins, Theo Romac, Diwan Abhinav, Harsh Goel, Jared M. McLendon, Chantal Allamargot, Helena Kenny, Renata O. Pereira, Dao-Fu Dai, Taha Gesalla, Eric T. Weatherford, Jennifer Streeter
TFEB promotes lysosomal biogenesis, autophagy, and lysosomal exocytosis. The present study characterized the consequence of inducible TFEB overexpression in cardiomyocytes in vivo. We generated cardiomyocyte-specific doxycycline inducible (Tet off) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ccac5f0096fe3ff197759d243230d9
https://doi.org/10.1101/2021.02.16.431474
https://doi.org/10.1101/2021.02.16.431474
Publikováno v:
The Journal of Infectious Diseases
Studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–infected patients and experimentally infected animals indicate a critical role for augmented expression of proinflammatory chemokines and cytokines in severe disease. Here, we
Autor:
Paige Noble, William H. Thiel, Chantal Allamargot, Isabella M. Grumbach, Emily K. Nguyen, Stefan Strack, Meng Wu, Kim Broadhurst, Olha M. Koval
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:1333-1345
Objective— The main objective of this study is to define the mechanisms by which mitochondria control vascular smooth muscle cell (VSMC) migration and impact neointimal hyperplasia. Approach and Results— The multifunctional CaMKII (Ca 2+ /calmodu
Autor:
Chantal Allamargot, Ivana Frech, Hongwei Xu, Guido Tricot, Xiaoyan Zhang, Fenghuang Zhan, Kristen L Coleman, Jiliang Xia, Randy Alan Nessler
Publikováno v:
EBioMedicine
EBioMedicine, Vol 18, Iss C, Pp 41-49 (2017)
EBioMedicine, Vol 18, Iss C, Pp 41-49 (2017)
High-dose chemotherapies to treat multiple myeloma (MM) can be life-threatening due to toxicities to normal cells and there is a need to target only tumor cells and/or lower standard drug dosage without losing efficacy. We show that pharmacologically
Autor:
Shubha Murthy, A. Brent Carter, Sara C. Sebag, Omar A. Jaffer, John D. Paschke, Christopher J. Winters, Chantal Allamargot, Isabella M. Grumbach, Olha M. Koval
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 310:L86-L94
The calcium and calmodulin-dependent kinase II (CaMKII) translates increases in intracellular Ca2+into downstream signaling events. Its function in pulmonary pathologies remains largely unknown. CaMKII is a well-known mediator of apoptosis and regula