Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Chansik Hong"'
Autor:
Xingyou Huang, Seok Choi, Wenhao Wu, Pawan Kumar Shahi, Jun Hyung Lee, Chansik Hong, Jae Yeoul Jun
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3997 (2024)
We examined the localization of the 5-hydroxytryptamine (5-HT) receptor and its effects on mouse colonic interstitial cells of Cajal (ICCs) using electrophysiological techniques. Treatment with 5-HT increased the pacemaker activity in colonic ICCs wi
Externí odkaz:
https://doaj.org/article/b871cc57a2844b93986f4b181fa1110c
Autor:
Young Jong Ko, Hong Moon Sohn, Yuria Jang, Mineon Park, Bora Kim, Beomchang Kim, Jae‐Il Park, Hoon Hyun, Byeongseok Jeong, Chansik Hong, Wonbong Lim
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 3, Pp n/a-n/a (2021)
Abstract Background The discovery of receptor activator of nuclear factor‐ĸB ligand (RANKL) as the final effector in the pathogenesis of osteoporosis has led to a better understanding of bone remodeling. When RANKL binds to its receptor (RANK), os
Externí odkaz:
https://doaj.org/article/df783077c68341ddb6de2432e728455d
Autor:
Seok Choi, Hyun Goo Kang, Mei Jin Wu, Han Yi Jiao, Dong Hoon Shin, Chansik Hong, Jae Yeoul Jun
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 6, Pp 2887-2899 (2018)
Background/Aims: Anoctamin1 (Ca2+-activated Cl- channel, ANO1) is a specific marker of the interstitial cells of Cajal (ICC) in the gastrointestinal tract, and are candidate proteins that can function as pacemaker channels. Recently, novel selective
Externí odkaz:
https://doaj.org/article/68f84e90a100416f9754030e6c83dfc8
Autor:
Chansik Hong, Byeongseok Jeong, Hyung Joon Park, Ji Yeon Chung, Jung Eun Lee, Jinsung Kim, Young-Cheul Shin, Insuk So
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The development of treatment for neurodegenerative diseases (NDs) such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis is facing medical challenges due to the increasingly aging population. H
Externí odkaz:
https://doaj.org/article/2098e40a9b7a43dd9996c06a6a95f36b
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Hypertension and aneurysm are frequently associated with autosomal dominant polycystic kidney disease (ADPKD) caused by polycystin-1 (PC1) mutations, which is closely related to endothelial dysfunction. PC1 is an atypical G-protein-coupled r
Externí odkaz:
https://doaj.org/article/6b1dac94af454f40b779ad80c02bde32
Autor:
Byung Joo Kim, Chansik Hong
Publikováno v:
Integrative Medicine Research, Vol 5, Iss 2, Pp 124-130 (2016)
Transient receptor potential (TRP) proteins are a family of ion channels, which are responsible for a wide array of cellular functions. In particular, TRP melastatin type (TRPM) 7 is expressed everywhere and permeable to divalent cations such as Mg2+
Externí odkaz:
https://doaj.org/article/169560ec0ae9468e84f238269df031f2
Publikováno v:
Cells, Vol 9, Iss 1, p 73 (2019)
The study of the structure−function relationship of ion channels has been one of the most challenging goals in contemporary physiology. Revelation of the three-dimensional (3D) structure of ion channels has facilitated our understanding of many of
Externí odkaz:
https://doaj.org/article/e8f4d3270f0e40478667f1aec3999cae
Autor:
null Seok Choi, null Jun Hyung Lee, null Dong Hoon Shin, null Wenhao Wu, null Xingyou Huang, null Chansik Hong, null Jae Yeoul Jun
Publikováno v:
Cellular and Molecular Biology. 69:67-73
Autor:
Byeongseok Jeong, Young Pyo Song, Ji Yeon Chung, Ki Chul Park, Jin Hyeong Kim, Insuk So, Chansik Hong
Publikováno v:
American Journal of Physiology-Cell Physiology.
Traditionally prescribed for mood disorders, tricyclic antidepressants (TCAs) have shown promising therapeutic effects on chronic neuralgia and irritable bowel syndrome. However, the mechanism by which these atypical effects manifest is unclear. Amon
Autor:
Kyu Joo Park, Tae Sik Sung, Jae Yeoul Jun, Insuk So, Chansik Hong, Byeongseok Jeong, Dongju Jeon
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:4911-4923
Background: Tricyclic antidepressants (TCAs) have been used to treat depression and were recently approved for treating irritable bowel syndrome (IBS) patients with severe or refractory IBS symptoms. However, the molecular mechanism of TCA action in