Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Chanse Fyffe"'
Autor:
Emily Capone, Charlotte E. Edling, Riccardo Ferro, Tania Maffucci, Marco Falasca, Simona Rapposelli, Aikaterini Emmanouilidi, Stefano Iacobelli, Gianluca Sala, Chanse Fyffe, Rossano Lattanzio, Simona Sestito
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-12 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background The very aggressive nature and low survival rate of pancreatic ductal adenocarcinoma (PDAC) dictates the necessity to find novel efficacious therapies. Recent evidence suggests that phosphoinositide 3-kinase (PI3K) and 3-phosphoinositide-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76164d71a8b9c7b30fe325fc5a67ef0b
http://link.springer.com/article/10.1186/s13046-019-1191-2
http://link.springer.com/article/10.1186/s13046-019-1191-2
Autor:
Lidia Sacchetto, M Piantelli, Syamsul Ahmad Arifin, Rossano Lattanzio, Owen J. Sansom, Tania Maffucci, Aleksandra Adamska, Ioanna Mavrommati, Charlotte E. Edling, Riccardo Ferro, Giovanna Chiorino, Gianluca Sala, Chanse Fyffe, V De Laurenzi, Marco Falasca
Publikováno v:
Oncogene. 37:6368-6382
The life expectancy for pancreatic cancer patients has seen no substantial changes in the last 40 years as very few and mostly just palliative treatments are available. As the five years survival rate remains around 5%, the identification of novel ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4764ddf3f7d05f62a37f46eff4fc0669
https://doi.org/10.1038/s41388-018-0390-1
https://doi.org/10.1038/s41388-018-0390-1
Autor:
Emmanouilidi, Aikaterini, Chanse Fyffe, Ferro, Riccardo, Edling, Charlotte, Capone, Emily, Sestito, Simona, Rapposelli, Simona, Lattanzio, Rossano, Iacobelli, Stefano, Sala, Gianluca, Maffucci, Tania, Falasca, Marco
Synthetic procedure followed for the synthesis of MP7 and characterization of intermediates. (DOCX 129 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2680d0b5edbf487ca61ebd3389f5f9c9
Autor:
Marco Falasca, Chanse Fyffe
Publikováno v:
Cancer Management and Research
It should be noted that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is a protein encoded by the PDPK1 gene, which plays a key role in the signaling pathways activated by several growth factors and hormones. PDK1 is a crucial kinase that func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5e223820d9dada7d4f51c3e64ba288
http://europepmc.org/articles/PMC3771848
http://europepmc.org/articles/PMC3771848
Publikováno v:
Current Pharmaceutical Design. 19:680-686
The last quarter of a century has witnessed remarkable progress in the understanding of phosphoinositide 3-kinases (PI3K) signalling and their involvement in different diseases such as cancer, diabetes and inflammation. Nevertheless, many questions r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b3e144d1717cf8fc95808997e394f8
https://doi.org/10.2174/138161213804581873
https://doi.org/10.2174/138161213804581873