Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Chanoch Kronman"'
Autor:
Inbar Cohen-Gihon, Ofir Israeli, Avital Tidhar, Anita Sapoznikov, Yentl Evgy, Dana Stein, Moshe Aftalion, David Gur, Irit Orr, Anat Zvi, Tamar Sabo, Chanoch Kronman, Reut Falach
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Severe manifestations of coronavirus disease 2019 (COVID-19) are mostly restricted to distinct groups of people who have preexisting morbidities. Most COVID-19 animal models develop a mild pathology that resolves within a relatively short period of t
Externí odkaz:
https://doaj.org/article/11b795ca9d3548e39310a72bb1c3c99f
Autor:
Anita Sapoznikov, Yoav Gal, Ron Alcalay, Yentl Evgy, Tamar Sabo, Chanoch Kronman, Reut Falach
Publikováno v:
Toxins, Vol 14, Iss 9, p 614 (2022)
Abrin is a highly toxic protein obtained from the seeds of the rosary pea plant Abrus precatorius, and it is closely related to ricin in terms of its structure and chemical properties. Both toxins inhibit ribosomal function, halt protein synthesis an
Externí odkaz:
https://doaj.org/article/7a0c3772835641058563a43767788911
Autor:
Reut Falach, Liat Bar-On, Shlomi Lazar, Tamar Kadar, Ohad Mazor, Moshe Aftalion, David Gur, Yentl Evgy, Ohad Shifman, Tamar Aminov, Ofir Israeli, Inbar Cohen-Gihon, Galia Zaide, Hila Gutman, Yaron Vagima, Efi Makdasi, Dana Stein, Ronit Rosenfeld, Ron Alcalay, Eran Zahavy, Haim Levy, Itai Glinert, Amir Ben-Shmuel, Tomer Israely, Sharon Melamed, Boaz Politi, Hagit Achdout, Shmuel Yitzhaki, Chanoch Kronman, Tamar Sabo
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Mice are normally unaffected by SARS coronavirus 2 (SARS-CoV-2) infection since the virus does not bind effectively to the murine version of the angiotensin-converting enzyme 2 (ACE2) receptor molecule. Here, we report that induced mild pulmonary mor
Externí odkaz:
https://doaj.org/article/f15ac9c77afc452ba0b7c4173a5bfbfe
Autor:
Anita Sapoznikov, Yoav Gal, Yentl Evgy, Moshe Aftalion, Shahaf Katalan, Tamar Sabo, Chanoch Kronman, Reut Falach
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12345 (2021)
Ricin toxin isolated from the castor bean (Ricinus communis) is one of the most potent and lethal molecules known. While the pathophysiology and clinical consequences of ricin poisoning by the parenteral route, i.e., intramuscular penetration, have b
Externí odkaz:
https://doaj.org/article/0b91a9f1acf747ff990e8c9006b2be9d
Autor:
Shahaf Katalan, Reut Falach, Amir Rosner, Michael Goldvaser, Tal Brosh-Nissimov, Ayana Dvir, Avi Mizrachi, Orr Goren, Barak Cohen, Yoav Gal, Anita Sapoznikov, Sharon Ehrlich, Tamar Sabo, Chanoch Kronman
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 2, Pp 173-183 (2017)
Pulmonary exposure to the plant toxin ricin leads to respiratory insufficiency and death. To date, in-depth study of acute respiratory distress syndrome (ARDS) following pulmonary exposure to toxins is hampered by the lack of an appropriate animal mo
Externí odkaz:
https://doaj.org/article/0312cae60c4e4943b8da78af916a5891
Autor:
Anita Sapoznikov, Reut Falach, Ohad Mazor, Ron Alcalay, Yoav Gal, Nehama Seliger, Tamar Sabo, Chanoch Kronman
Publikováno v:
Toxins, Vol 7, Iss 11, Pp 4817-4831 (2015)
Ricin, a plant-derived exotoxin, inhibits protein synthesis by ribosomal inactivation. Due to its wide availability and ease of preparation, ricin is considered a biothreat, foremost by respiratory exposure. We examined the in vivo interactions betwe
Externí odkaz:
https://doaj.org/article/48224fcba03b4554a5825704a11df2d3
Autor:
Reut Falach, Anita Sapoznikov, Yentl Evgy, Moshe Aftalion, Arik Makovitzki, Avi Agami, Avishai Mimran, Elad Lerer, Alon Ben David, Ran Zichel, Shahaf Katalan, Amir Rosner, Tamar Sabo, Chanoch Kronman, Yoav Gal
Publikováno v:
Toxins, Vol 12, Iss 6, p 354 (2020)
Ricin, a plant-derived toxin originating from the seeds of Ricinus communis (castor bean plant), is one of the most lethal toxins known. To date, there is no approved post-exposure therapy for ricin exposures. This work demonstrates for the first tim
Externí odkaz:
https://doaj.org/article/8983b4478e4848209053341e5c0b4dfd
Autor:
Ron Alcalay, Reut Falach, Yoav Gal, Anita Sapoznikov, Tamar Sabo, Chanoch Kronman, Ohad Mazor
Publikováno v:
Antibodies, Vol 9, Iss 2, p 11 (2020)
Abrin, a toxin isolated from the seeds of Abrus precatorius (jequirity pea) is considered a biological threat agent by the Center for Disease Control and Prevention. To date, there is no effective postexposure treatment for abrin poisoning, and effor
Externí odkaz:
https://doaj.org/article/a1f31c86cffa4374b4b8a2dedc30ca96
Autor:
Yoav Gal, Anita Sapoznikov, Reut Falach, Ohad Mazor, Ron Alcalay, Eytan Elhanany, Moshe Aftalion, Sharon Ehrlich, Chanoch Kronman, Tamar Sabo
Publikováno v:
Antibodies, Vol 9, Iss 1, p 4 (2020)
Abrin and ricin are potent AB toxins, which are considered biological threats. To date, there are no approved treatments against abrin or ricin intoxications. Previously, we showed that the administration of polyclonal anti-abrin antibodies to mice t
Externí odkaz:
https://doaj.org/article/e3eb9387e6c245c3aa693a76d797f4cf
Autor:
Yoav Gal, Ohad Mazor, Ron Alcalay, Nehama Seliger, Moshe Aftalion, Anita Sapoznikov, Reut Falach, Chanoch Kronman, Tamar Sabo
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 496-504 (2014)
Ricin, a highly toxic plant-derived toxin, is considered a potential weapon in biological warfare due to its high availability and ease of preparation. Pulmonary exposure to ricin results in the generation of an acute edematous inflammation followed
Externí odkaz:
https://doaj.org/article/15718d73a41d4fc19d00296199a0e87f