Zobrazeno 1 - 10
of 2 374
pro vyhledávání: '"Channelrhodopsin"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Vision restoration is one of the most promising applications of optogenetics. However, it is limited due to the poor-sensitivity, slow-kinetics and narrow band absorption spectra of opsins. Here, a detailed theoretical study of retinal gangl
Externí odkaz:
https://doaj.org/article/8f748d89ccbd44a29e318c5e5ae21b9e
Autor:
Sen‐Miao Li, Dian‐Dian Wang, Dan‐Hua Liu, Xiao‐Yan Meng, Zhizhong Wang, Xitong Guo, Qian Liu, Pei‐Pei Liu, Shu‐Ang Li, Songwei Wang, Run‐Zhou Yang, Yuming Xu, Longde Wang, Jian‐Sheng Kang
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Parkinson's disease (PD) is a mitochondria‐related neurodegenerative disease characterized by locomotor deficits and loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Majority of PD research primarily focused o
Externí odkaz:
https://doaj.org/article/62f42c40c5de4a5db3198e57338533c3
Akademický článek
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Autor:
Lillian Yang, John H. Martin
Publikováno v:
Brain Stimulation, Vol 16, Iss 3, Pp 759-771 (2023)
Background: Neural activity helps construct neural circuits during development and this function is leveraged by neuromodulation protocols to promote connectivity and repair in maturity. Neuromodulation targeting the motor cortex (MCX) strengthens co
Externí odkaz:
https://doaj.org/article/70354b55ad2548019b09b1fc7b797f0b
Akademický článek
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Autor:
Tianyu Terry Gao, Teak‐Jung Oh, Kritika Mehta, Yu‐En Andrew Huang, Tyler Camp, Huaxun Fan, Jeong Won Han, Collin Michael Barnes, Kai Zhang
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background Opsin‐based optogenetics has emerged as a powerful biomedical tool using light to control protein conformation. Such capacity has been initially demonstrated to control ion flow across the cell membrane, enabling precise control
Externí odkaz:
https://doaj.org/article/634d0495b07743afac5bb57cff0749bf
Autor:
Daniel J. Rindner, Gyorgy Lur
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The ability to control synaptic communication is indispensable to modern neuroscience. Until recently, only single-pathway manipulations were possible due to limited availability of opsins activated by distinct wavelengths. However, extensive protein
Externí odkaz:
https://doaj.org/article/01840d4eedd14d6f859bba57649bcbbe
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Self-grooming plays an essential role in hygiene maintenance, thermoregulation, and stress response. However, the neural populations involved in self-grooming remain largely unknown. The paraventricular hypothalamic nucleus (PVH) has been im
Externí odkaz:
https://doaj.org/article/a2ea85baf3324f4eadae8dbeb68eba73
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1856 (2023)
Alzheimer’s disease (AD) is the most common form of dementia, resulting in disability and mortality. The global incidence of AD is consistently surging. Although numerous therapeutic agents with promising potential have been developed, none have su
Externí odkaz:
https://doaj.org/article/a01d5fba04264434b9d544a1c4dbac41
Autor:
Schiewer, Enrico
Mikrobielle Rhodopsine sind Membranproteine, die Lichtsensitivität mit sensorischer, enzymatischer oder ionenleitender Funktion in einem Protein vereinen. Ihre strukturelle Kompaktheit macht lichtgetriebene Ionenpumpen und lichtgesteuerte Kanalrhodo
Externí odkaz:
http://edoc.hu-berlin.de/18452/29801
