Vi polysaccharide and conjugated vaccines afford similar early, IgM or IgG-independent control of infection but boosting with conjugated Vi vaccines sustains the efficacy of immune responses.

Autor: Jossi SE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Arcuri M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.; GSK Vaccines Institute for Global Health SRL, Siena, Italy., Alshayea A; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Persaud RR; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Marcial-Juárez E; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Palmieri E; GSK Vaccines Institute for Global Health SRL, Siena, Italy., Di Benedetto R; GSK Vaccines Institute for Global Health SRL, Siena, Italy., Pérez-Toledo M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Pillaye J; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Channell WM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Schager AE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Lamerton RE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Cook CN; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Goodall M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Haneda T; Laboratory of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan., Bäumler AJ; Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, CA, United States., Jackson-Jones LH; Division of Biomedical and Life Sciences, Lancaster University, Lancaster, United Kingdom., Toellner KM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., MacLennan CA; Bill & Melinda Gates Foundation, London, United Kingdom.; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Henderson IR; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, Australia., Micoli F; GSK Vaccines Institute for Global Health SRL, Siena, Italy., Cunningham AF; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Mar 23; Vol. 14, pp. 1139329. Date of Electronic Publication: 2023 Mar 23 (Print Publication: 2023).

HRMAn 2.0: Next-generation artificial intelligence-driven analysis for broad host-pathogen interactions.

Autor: Fisch D; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, UK.; Host-Toxoplasma Interaction Laboratory, The Francis Crick Institute, London, UK., Evans R; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, UK.; Host-Toxoplasma Interaction Laboratory, The Francis Crick Institute, London, UK., Clough B; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, UK., Byrne SK; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, UK., Channell WM; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, UK., Dockterman J; Department of Immunology, Duke University Medical Center, Durham, North Carolina, USA., Frickel EM; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, UK.

Publikováno v: Cellular microbiology [Cell Microbiol] 2021 Jul; Vol. 23 (7), pp. e13349. Date of Electronic Publication: 2021 May 16.

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface.

Autor: Domínguez-Medina CC; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Pérez-Toledo M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK.; Medical Research Unit on Immunochemistry, Specialties Hospital, National Medical Centre 'Siglo XXI' Mexican Institute for Social Security, Mexico City, Mexico., Schager AE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Marshall JL; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK., Cook CN; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Bobat S; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Hwang H; School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta GA, 30332, USA., Chun BJ; School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta GA, 30332, USA., Logan E; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Cape Town, Western Cape, 7925, South Africa., Bryant JA; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Channell WM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK., Morris FC; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Jossi SE; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK., Alshayea A; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK., Rossiter AE; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Barrow PA; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Leicestershire, LE12 5RD, UK., Horsnell WG; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Cape Town, Western Cape, 7925, South Africa., MacLennan CA; Jenner Institute, Nuffield Department of Medicine, Old Road Campus Research Building, Roosevelt Drive, University of Oxford, Oxford, OX3 7DQ, UK., Henderson IR; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK., Lakey JH; Institute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne, NE2 4HH, UK., Gumbart JC; School of Physics, Georgia Institute of Technology, Atlanta, GA, 30332, USA., López-Macías C; Medical Research Unit on Immunochemistry, Specialties Hospital, National Medical Centre 'Siglo XXI' Mexican Institute for Social Security, Mexico City, Mexico., Bavro VN; School of Life Sciences, University of Essex, Wivenhoe Park, Colchester, CO4 3SQ, UK. v.bavro@essex.ac.uk., Cunningham AF; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, B15 2TT, UK. a.f.cunningham@bham.ac.uk.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, B15 2TT, UK. a.f.cunningham@bham.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2020 Feb 12; Vol. 11 (1), pp. 851. Date of Electronic Publication: 2020 Feb 12.