Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Chanitra Thuwajit"'
Autor:
Chanida Thinyakul, Yasuhisa Sakamoto, Mayuko Shimoda, Yanliang Liu, Suyanee Thongchot, Omnia Reda, Akihiro Nita, Romgase Sakamula, Somponnat Sampattavanich, Ayato Maeda, Paweenapon Chunthaboon, David Nduru, Mayumi Niimura, Yohei Kanamori, Peti Thuwajit, Keiichi I. Nakayama, Kun-Liang Guan, Yorifumi Satou, Chanitra Thuwajit, Toshiro Moroishi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Cancer cells adeptly manipulate the tumor microenvironment (TME) to evade host antitumor immunity. However, the role of cancer cell-intrinsic signaling in shaping the immunosuppressive TME remains unclear. Here, we found that the Hippo pathw
Externí odkaz:
https://doaj.org/article/78c73de30af2440f83df06f6fbe4a097
Autor:
Suyanee Thongchot, Krittaya Aksonnam, Jaturawitt Prasopsiri, Malee Warnnissorn, Doonyapat Sa-nguanraksa, Pornchai O-Charoenrat, Peti Thuwajit, Pa-thai Yenchitsomanus, Chanitra Thuwajit
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Triple-negative breast cancer (TNBC), known for its aggressiveness and limited treatment options, presents a significant challenge. Adoptive cell transfer, involving the ex vivo generation of antigen-specific T cells from peripher
Externí odkaz:
https://doaj.org/article/541e33883a9746f09090f1d15e1eeb00
Autor:
Thaweesak Chieochansin, Kamonpan Sanachai, Nitchakan Darai, Wannasiri Chiraphapphaiboon, Kornkan Choomee, Pa-thai Yenchitsomanus, Chanitra Thuwajit, Thanyada Rungrotmongkol
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36654- (2024)
Our study employed molecular dynamics (MD) simulations to assess the binding affinity between short peptides derived from the tumor-associated antigen glypican 3 (GPC3) and the major histocompatibility complex (MHC) molecule HLA-A*11:01 in hepatocell
Externí odkaz:
https://doaj.org/article/6586fa72f95b489a8493964d37d7ddc5
Autor:
Narongrid Seesawad, Piyalitt Ittichaiwong, Thapanun Sudhawiyangkul, Phattarapong Sawangjai, Peti Thuwajit, Paisarn Boonsakan, Supasan Sripodok, Kanyakorn Veerakanjana, Komgrid Charngkaew, Ananya Pongpaibul, Napat Angkathunyakul, Narit Hnoohom, Sumeth Yuenyong, Chanitra Thuwajit, Theerawit Wilaiprasitporn
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 5, Pp 514-523 (2024)
Background: Deep learning models for patch classification in whole-slide images (WSIs) have shown promise in assisting follicular lymphoma grading. However, these models often require pathologists to identify centroblasts and manually provide refined
Externí odkaz:
https://doaj.org/article/0c94c612c58b45a59a13709fb48791dd
Autor:
Phimmada Hatthakarnkul, Kathryn Pennel, Peter Alexander, Hester vanWyk, Antonia Roseweir, Jitwadee Inthagard, Jennifer Hay, Ditte Andersen, Noori Maka, James Park, Campbell Roxburgh, Chanitra Thuwajit, Donald McMillan, Joanne Edwards
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract Colorectal cancer (CRC) is a heterogenous malignancy and research is focused on identifying novel ways to subtype patients. In this study, a novel classification system, tumour microenvironment score (TMS), was devised based on Klintrup–M
Externí odkaz:
https://doaj.org/article/7cd476cd4b6e49e793cf072a26acb064
Autor:
Panisa Janyasupab, Kodchanan Singhanat, Malee Warnnissorn, Peti Thuwajit, Apichat Suratanee, Kitiporn Plaimas, Chanitra Thuwajit
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 896 (2024)
Breast cancer has the highest diagnosis rate among all cancers. Tumor budding (TB) is recognized as a recent prognostic marker. Identifying genes specific to high-TB samples is crucial for hindering tumor progression and metastasis. In this study, we
Externí odkaz:
https://doaj.org/article/4341cbbb181e494c81135e7a5c016cbf
Autor:
Nisa Chuangchot, Pranisa Jamjuntra, Supaporn Yangngam, Piriya Luangwattananun, Suyanee Thongchot, Mutita Junking, Peti Thuwajit, Pa-Thai Yenchitsomanus, Chanitra Thuwajit
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Carcinoma-associated fibroblasts (CAFs) play a critical role in cancer progression and immune cell modulation. In this study, it was aimed to evaluate the roles of CAFs-derived IL-6 in doxorubicin (Dox) resistance and PD-L1-mediat
Externí odkaz:
https://doaj.org/article/eb48fc516ca1446f87621c44ad9aef9f
Autor:
Simran Venkatraman, Brinda Balasubramanian, Chanitra Thuwajit, Jaroslaw Meller, Rutaiwan Tohtong, Somchai Chutipongtanate
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
MYC activation is a known hallmark of cancer as it governs the gene targets involved in various facets of cancer progression. Of interest, MYC governs oncometabolism through the interactions with its partners and cofactors, as well as cancer immunity
Externí odkaz:
https://doaj.org/article/c21297c950af4c5e95402930fd4df6dd
Autor:
Sumeth Yuenyong, Paisarn Boonsakan, Supasan Sripodok, Peti Thuwajit, Komgrid Charngkaew, Ananya Pongpaibul, Napat Angkathunyakul, Narit Hnoohom, Chanitra Thuwajit
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionDetection and counting of Centroblast cells (CB) in hematoxylin & eosin (H&E) stained whole slide image (WSI) is an important workflow in grading Lymphoma. Each high power field (HPF) patch of a WSI is inspected for the number of CB cells
Externí odkaz:
https://doaj.org/article/facc13b7ac3549eab0583841bfc8952c
Autor:
Niphat Jirapongwattana, Suyanee Thongchot, Ananya Pongpaibul, Atthaphorn Trakarnsanga, Jean Quinn, Peti Thuwajit, Chanitra Thuwajit, Joanne Edwards
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304666 (2024)
Colorectal cancer (CRC) is the third most common malignancy cause of cancer-related mortality worldwide. Epithelial-mesenchymal transition (EMT) promotes cancer metastasis and a tumour-based Glasgow EMT score was associated with adverse clinical feat
Externí odkaz:
https://doaj.org/article/ffd6bd702c7948f6abf244b779d1c36a