Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Changzhu Duan"'
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Hepatitis B virus (HBV) infection is one of main contributors to poor prognosis and rapid progression of hepatocellular cancer (HCC). We previously identified the important role of the phosphorylation of ubiquitin-like with PHD and ring fing
Externí odkaz:
https://doaj.org/article/d33221c48fb5470699b7172e4702acc3
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Lung cancer has emerged as one of the most common cancers in recent years. The mitochondrial electron transport chain (ETC) is closely connected with metabolic pathways and inflammatory response. However, the influence of ETC-associated g
Externí odkaz:
https://doaj.org/article/73e83b2315c44c968e300b2a29b4b198
Publikováno v:
Protein & Cell, Vol 8, Iss 3, Pp 202-218 (2016)
ABSTRACT UHRF2 is a ubiquitin-protein ligase E3 that regulates cell cycle, genomic stability and epigenetics. We conducted a co-immunoprecipitation assay and found that TIP60 and HDAC1 interact with UHRF2. We previously demonstrated that UHRF2 regula
Externí odkaz:
https://doaj.org/article/d5225e75a8374e6d9e5402fd3996de65
Publikováno v:
Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 38(10)
Ubiquitination is one of the reversible protein post-translational modifications, in which ubiquitin molecules bind to the target protein in a cascade reaction of ubiquitin activating enzymes, ubiquitin conjugating enzymes, and ubiquitin ligases. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ac54982713e064966da9f42e604c451
https://pubmed.ncbi.nlm.nih.gov/36305417
https://pubmed.ncbi.nlm.nih.gov/36305417
Autor:
Zhaodi Li, Shangjing Liu, Juan Chen, Rongjuan Chen, Guanhua Qian, Siyuan Chen, Shiming Jiang, Kejia Wu, Ni Tang, Changzhu Duan, Jingjie Sun, Fengjuan Cheng, Yong Chen, Xian-Yun Fang
Publikováno v:
Hepatology International. 15:707-719
The major cause of Hepatocellular carcinoma (HCC) is acute or chronic infection caused by hepatotropic viruses and HBV infection is the main cause. UHRF2, a ubiquitin-protein ligase E3, is associated with cancer development. This study aimed to inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760301568ea72fc90246c775e1e67d8d
https://doi.org/10.1007/s12072-021-10172-z
https://doi.org/10.1007/s12072-021-10172-z
Publikováno v:
Cancer Letters. 534:215631
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a77a83a4bfcf593bfa0dda6a04a0b35
https://doi.org/10.1016/j.canlet.2022.215631
https://doi.org/10.1016/j.canlet.2022.215631
Autor:
Yangyang Wang, Rongjuan Chen, Shengyuan Zeng, Xinke Yan, Changzhu Duan, Fengjuan Cheng, Ting Zhang
Publikováno v:
Biotechnology Letters. 40:1181-1188
To investigate the interaction of E3 ubiquitin ligase UHRF2 with p21 and the mechanism of UHRF2 in repairing DNA damage caused by hydroxyurea (HU) in HEK293 cells. Western blotting indicated that the overexpression of UHRF2 reduced the level of p21,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578000813c755d9c169d14e5282e8c9c
https://doi.org/10.1007/s10529-018-2577-5
https://doi.org/10.1007/s10529-018-2577-5
UHRF2 promotes Hepatocellular Carcinoma Progression by Upregulating ErbB3/Ras/Raf Signaling Pathway.
Publikováno v:
International Journal of Medical Sciences; 2021, Vol. 18 Issue 14, p3097-3105, 9p
Autor:
Shengyuan Zeng, Ya-Lan Wang, Ting Zhang, Linglin Zhao, Changzhu Duan, Junxia Chen, Lu Bai, Zheng Zhang
Publikováno v:
International Journal of Molecular Medicine
Ubiquitin-like with PHD and ring finger domains 2 (UHRF2) is a multi-domain E3 ubiquitin ligase which is involved in epigenetic regulation and plays an essential role in tumorigenesis. However, the role of UHRF2 in histone H3 acetylation has not yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0d92d5002171268905888fd7433f24
http://europepmc.org/articles/PMC5179198
http://europepmc.org/articles/PMC5179198
Publikováno v:
Protein & Cell
Protein & Cell, Vol 8, Iss 3, Pp 202-218 (2016)
Protein & Cell, Vol 8, Iss 3, Pp 202-218 (2016)
UHRF2 is a ubiquitin-protein ligase E3 that regulates cell cycle, genomic stability and epigenetics. We conducted a co-immunoprecipitation assay and found that TIP60 and HDAC1 interact with UHRF2. We previously demonstrated that UHRF2 regulated H3K9a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4480b4666b62c8ac4ede64f0987d599
http://europepmc.org/articles/PMC5326618
http://europepmc.org/articles/PMC5326618