Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Changyu Kang"'
Autor:
Ji Eun Kim, Changyu Kang, Phatcharaporn Budluang, Natpaphan Yawut, Il-Rae Cho, Yun Ju Choi, Jaejeong Kim, Sanghyun Ju, Beomgu Lee, Dong Hyun Sohn, Hyung-Soon Yim, Kyeong Won Lee, Jinsol Han, Youngmi Jung, Ho Young Kang, Jin Kyoon Park, Yunjin Jung, Dae Youn Hwang, Young-Hwa Chung
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
As our previous study revealed that N-benzyl-N-methyldecan-1-amine (BMDA), a new molecule originated from Allium sativum, exhibits anti-neoplastic activities, we herein explored other functions of the compound and its derivative [decyl-(4-methoxy-ben
Externí odkaz:
https://doaj.org/article/35bcd7a36ac2466ea03488283a585c87
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2638 (2023)
In our previous study, riluzole azo-linked to salicylic acid (RAS) was prepared as a colon-targeted prodrug of riluzole (RLZ) to facilitate the repositioning of RLZ as an anticolitic drug. RAS is more effective against rat colitis than RLZ and sulfas
Externí odkaz:
https://doaj.org/article/9ea6f3d0f61a46de8c9dd9642f64ae1b
Autor:
Changyu Kang, Jaejeong Kim, Sanghyun Ju, Heeyeong Cho, Hyun Young Kim, In-Soo Yoon, Jin-Wook Yoo, Yunjin Jung
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 41 (2022)
We designed colon-targeted trans-cinnamic acid (tCA) and synthesized its conjugates with glutamic acid (tCA-GA) and aspartic acid (tCA-AA). We evaluated the anti-colitic activity of colon-targeted tCA using a dinitrobenzenesulfonic acid-induced rat c
Externí odkaz:
https://doaj.org/article/0f8bcc681094467e8bdca9d4cfcb9aff
Autor:
Changyu Kang, Jaejeong Kim, Sanghyun Ju, Sohee Park, Jin-Wook Yoo, In-Soo Yoon, Min-Soo Kim, Yunjin Jung
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 684 (2022)
Dapsone (DpS) is an antimicrobial and antiprotozoal agent, especially used to treat leprosy. The drug shares a similar mode of action with sulfonamides. Additionally, it possesses anti-inflammatory activity, useful for treating autoimmune diseases. H
Externí odkaz:
https://doaj.org/article/1f4fbaa9658a4785bfa7994c12e1ab99
Autor:
Seongkeun Jeong, Changyu Kang, Sohee Park, Sanghyun Ju, Jin-Wook Yoo, In-Soo Yoon, Hwayoung Yun, Yunjin Jung
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1092 (2021)
Tranilast (TRL), a synthetic derivative of a tryptophan metabolite, is an anti-allergic drug used to treat bronchial asthma. We investigated how TRL activated the nuclear factor-erythroid 2 p45-related factor 2 (Nrf2)-hemeoxygenase-1 (HO-1) pathway b
Externí odkaz:
https://doaj.org/article/d4c7830b0e65428d8b8d171c5bd527fb
Autor:
Sohee Park, Changyu Kang, Jaejeong Kim, Sanghyun Ju, Jin-Wook Yoo, In-Soo Yoon, Min-Soo Kim, Jaewon Lee, Yunjin Jung
Publikováno v:
Molecular Pharmaceutics. 19:3784-3794
Riluzole (RLZ) is a neuroprotective drug indicated for amyotrophic lateral sclerosis. To examine the feasibility of RLZ for repositioning as an anti-inflammatory bowel disease (IBD) drug, RLZ (2, 5, and 10 mg/kg) was administered orally to rats with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ead67ab3c43726d156e0918e7349791
https://doi.org/10.1021/acs.molpharmaceut.2c00255
https://doi.org/10.1021/acs.molpharmaceut.2c00255
Publikováno v:
Pharmacological reports : PR.
Chloroquine (CQ) is an effective and safe antimalarial drug that is also used as a disease-modifying antirheumatic drug. Recent studies have shown that CQ can sensitize cancer cells to anti-cancer therapies.In this study, we investigated the molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492462609dead5703dd7bf291ef16296
https://pubmed.ncbi.nlm.nih.gov/36508076
https://pubmed.ncbi.nlm.nih.gov/36508076
Autor:
Changyu Kang, Seongkeun Jeong, Jaejeong Kim, Sanghyun Ju, Eunok Im, Gwangbeom Heo, Soyeong Park, Jin‐Wook Yoo, Juho Lee, In‐Soo Yoon, Yunjin Jung
Publikováno v:
Journal of pineal researchREFERENCES. 74(1)
N-Acetylserotonin (NAS) is an intermediate in the melatonin biosynthetic pathway. We investigated the anti-inflammatory activity of NAS by focusing on its chemical feature oxidizable to an electrophile. NAS was readily oxidized by reaction with HOCl,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b04b7a8568c6d007bb591a281c22c4
https://pubmed.ncbi.nlm.nih.gov/36214640
https://pubmed.ncbi.nlm.nih.gov/36214640
Autor:
Jung, Changyu Kang, Jaejeong Kim, Sanghyun Ju, Sohee Park, Jin-Wook Yoo, In-Soo Yoon, Min-Soo Kim, Yunjin
Publikováno v:
Pharmaceutics; Volume 14; Issue 3; Pages: 684
Dapsone (DpS) is an antimicrobial and antiprotozoal agent, especially used to treat leprosy. The drug shares a similar mode of action with sulfonamides. Additionally, it possesses anti-inflammatory activity, useful for treating autoimmune diseases. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::c4e17b0b5c4cbc4171a3713fc173ce64
Autor:
In-Soo Yoon, Yunjin Jung, Jin-Wook Yoo, Sohee Park, Changyu Kang, Sanghyun Ju, Seongkeun Jeong, Hwayoung Yun
Publikováno v:
Pharmaceuticals
Volume 14
Issue 11
Pharmaceuticals, Vol 14, Iss 1092, p 1092 (2021)
Volume 14
Issue 11
Pharmaceuticals, Vol 14, Iss 1092, p 1092 (2021)
Tranilast (TRL), a synthetic derivative of a tryptophan metabolite, is an anti-allergic drug used to treat bronchial asthma. We investigated how TRL activated the nuclear factor-erythroid 2 p45-related factor 2 (Nrf2)-hemeoxygenase-1 (HO-1) pathway b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d1d60eba7e896a2be73c4bd6d50686