Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Changyoung Jung"'
Publikováno v:
Synthesis. 51:3471-3476
Total syntheses of (–)-7-epi-alexine and (+)-alexine were achieved by using stereoselective allylation via a functionalized pyrrolidine obtained from an extended chiral 1,3-oxazine. The synthetic strategies include pyrrolidine formation via oxazine
Publikováno v:
Tetrahedron Letters. 60:235-239
The stereoselective allylation of acyclic chiral α-amino aldimines affording vicinal diamines, mediated by various Lewis acids (TiCl4, SnCl4, MgBr2·OEt2, BF3·OEt2, ZnCl2), is described. The TiCl4-mediated allylation of an α-N-Boc aldimine afforde
Publikováno v:
Tetrahedron Letters. 59:2422-2425
The asymmetric total syntheses of (+)-2,5-dideoxy-2,5-imino- d -glucitol [(+)-DGDP] 1 and (−)-1-deoxymannojirimycin [(−)-DMJ] 2 were achieved using an extended chiral 1,3-oxazine. The key synthetic strategies included extension of the chirality o
Autor:
In-Soo Myeong, Jin-Seok Kim, Changyoung Jung, Yong-Taek Lee, Muyng-Gyu Park, Hwan-Hee Jeon, Won-Hun Ham
Publikováno v:
Synthesis. 50:2058-2066
The stereoselective allylations of β-amino-α-hydroxy aldehydes are described. Several Lewis acids (BF3·OEt2, SnCl4, TiCl4, ZnCl2, and MgBr2·OEt2) were utilized in the allylations. The allylation of anti-β-NHCbz-α-OTBS substrate mediated by
Publikováno v:
Tetrahedron. 74:506-511
Stereoselective allylation of N-p-methoxyphenyl (PMP)-substituted α-hydroxy aldimines is described. Several Lewis acids (BF3·OEt2, SnCl4, TiCl4, ZnCl2, and MgBr2·OEt2) were employed to mediate the allylation reactions. The addition of the allyl gr
Autor:
Changyoung Jung, Seung Jong Lee, Jin-Seok Kim, In-Hae Ye, Won-Hun Ham, Yong-Taek Lee, Jihun Kang, Sanghyun Lee, In-Soo Myeong, Seok-Hwi Park
Publikováno v:
Tetrahedron: Asymmetry. 28:1053-1060
Stereoselective allylation reactions of acyclic and chiral α-amino-β-hydroxy aldehydes affording chiral β-amino-α,γ-diols are described. Several Lewis acids (BF 3 ·OEt 2 , SnCl 4 , TiCl 4 , ZnCl 2 , and MgBr 2 ·OEt 2 ) were employed to mediate
Autor:
Won-Hun Ham, In-Soo Myeong, Changyoung Jung, Yong-Taek Lee, Jin-Seok Kim, Jong-Cheol Kang, Seok-Hwi Park
Publikováno v:
Tetrahedron: Asymmetry. 27:823-828
The total synthesis of (−)-conduramine A-1 was achieved by using a diastereomerically enriched syn , anti -oxazine intermediate. The key steps in this strategy were the stereoselective extension of the chirality of syn , anti -oxazine, a Wittig rea
Autor:
In-Soo Myeong, Gyu-Jin Lee, Won-Hun Ham, Gun-Woo Kim, Gyung-Ho Choo, Yong-Taek Lee, Jong-Cheol Kang, Seok-Hwi Park, Jin-Seok Kim, Changyoung Jung
Publikováno v:
Tetrahedron: Asymmetry. 27:171-176
The stereoselective total synthesis of (+)-radicamine B was achieved using commercially available d -4-hydroxy-phenylglycine via chiral 1,3-oxazine, which has been applied to synthesis of amino polyols such as DAB-1, d -fagomine, and phytosphingosine
Publikováno v:
Tetrahedron: Asymmetry. 26:657-661
Concise and stereocontrolled syntheses of (+)-1-deoxynojirimycin and (2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine [(+)-DMDP] were achieved via a diastereomerically enriched oxazine intermediate. The key strategies include the use of 1,3-oxazi
Autor:
Sung-Soo Kim, Seok-Hwi Park, Seong-Soo Kim, Won-Hun Ham, Xiangdan Jin, Kee-Young Lee, Changyoung Jung, Jong-Cheol Kang
Publikováno v:
Org. Biomol. Chem.. 13:4539-4550
Concise and stereocontrolled syntheses of (+)-hyacinthacine A2 and sphingofungin B were achieved via a diastereomerically enriched oxazine intermediate. The key strategies include palladium(0)-catalyzed intramolecular oxazine formation and diastereos