Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Changyou, Zhan"'
Autor:
Yulu Wang, Yifang Sun, Zhaoling Shen, Cong Wang, Jun Qian, Qiyu Mao, Yajie Wang, Wenping Song, Yu Kong, Changyou Zhan, Zhenguo Chen, Dimiter S. Dimitrov, Zhenlin Yang, Shibo Jiang, Fan Wu, Lu Lu, Tianlei Ying, Lei Sun, Yanling Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Nipah virus infection, one of the top priority diseases recognized by the World Health Organization, underscores the urgent need to develop effective countermeasures against potential epidemics and pandemics. Here, we identify a fully human
Externí odkaz:
https://doaj.org/article/46eb885c817a4c7290a486dfc966cb8f
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Intrahepatic accumulation dominates organ distribution for most nanomedicines. However, obscure intrahepatic fate largely hampers regulation on their in vivo performance. Herein, PEGylated liposomal doxorubicin is exploited to clarify the in
Externí odkaz:
https://doaj.org/article/d781b2f2daa64ebfa45b98ae2cc299e0
Autor:
Wenjing Zai, Min Yang, Kuan Jiang, Juan Guan, Huijing Wang, Kongying Hu, Chao Huang, Jieliang Chen, Wei Fu, Changyou Zhan, Zhenghong Yuan
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract This study aimed to develop a pan-genotypic and multifunctional small interfering RNA (siRNA) against hepatitis B virus (HBV) with an efficient delivery system for treating chronic hepatitis B (CHB), and explore combined RNA interference (RN
Externí odkaz:
https://doaj.org/article/77699b63f4cc4c27be14f71bca96fa57
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 808-820 (2024)
Folic acid is a fully oxidized synthetic folate with high bioavailability and stability which has been extensively prescribed to prevent congenital disabilities. Here we revealed the immunosuppressive effect of folic acid by targeting splenic margina
Externí odkaz:
https://doaj.org/article/8cd3e9c02bba415792ddb10d5445ad44
Autor:
Qianqian Long, Xinmin Zhao, Lili Gao, Mengyuan Liu, Feng Pan, Xihui Gao, Changyou Zhan, Yang Chen, Jialei Wang, Jun Qian
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 744 (2024)
Background: Nanoparticles conjugated with fluorescent probes have versatile applications, serving not only for targeted fluorescent imaging but also for evaluating the in vivo profiles of designed nanoparticles. However, the relationship between fluo
Externí odkaz:
https://doaj.org/article/4f873eece64b43c8818cf17e980b1d0c
Autor:
Qianwen Shao, Tianhao Ding, Feng Pan, Guanghui Li, Shun Shen, Jun Qian, Changyou Zhan, Xiaoli Wei
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 6, Pp 855-866 (2022)
Liposomes have been widely investigated as a class of promising antibiotic delivery systems for the treatment of life-threatening bacterial infections. However, the inevitable formation of protein corona on the liposomal surface can heavily impact in
Externí odkaz:
https://doaj.org/article/f410be79097e4bc8938b3c125a9087f7
Autor:
Songli Wang, Ruifeng Wang, Nana Meng, Linwei Lu, Jun Wang, Jianfen Zhou, Jiasheng Lu, Qianzhu Xu, Cao Xie, Changyou Zhan, Yao Li, Yang Yu, Weiyue Lu, Min Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 4, Pp 2000-2013 (2022)
Thrombolytic agents have thus far yielded limited therapeutic benefits in the treatment of thrombotic disease due to their short half-life, low targeting ability, and association with serious adverse reactions, such as bleeding complications. Inspire
Externí odkaz:
https://doaj.org/article/b8b1fbaf2ef344b191bfd6d943de062b
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract Photocleavable prodrugs enable controllable drug delivery to target sites modulated by light irradiation. However, the in vivo utility is usually hindered by their insolubility and inefficient delivery. In this study, we report a simple stra
Externí odkaz:
https://doaj.org/article/28f8bd8c373346b2ae97fd70b1cfd1c0
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 1, Pp 120-128 (2021)
Glucose transporter (GLUT)-mediated transcytosis has been validated as an efficient method to cross the blood-brain barrier and enhance brain transport of nanomedicines. However, the transcytosis process remains elusive. Glycopeptide-modified nanodis
Externí odkaz:
https://doaj.org/article/07f8bc71c5744b0b91fc412a155b3ad0
Autor:
Kaiqi Long, Yang Yang, Wen Lv, Kuan Jiang, Yafei Li, Amy Cheuk Yin Lo, Wai Ching Lam, Changyou Zhan, Weiping Wang
Publikováno v:
Advanced Science, Vol 8, Iss 20, Pp n/a-n/a (2021)
Abstract Retinoblastoma is one of the most severe ocular diseases, of which current chemotherapy is limited to the repetitive intravitreal injections of chemotherapeutics. Systemic drug administration is a less invasive route; however, it is also les
Externí odkaz:
https://doaj.org/article/c41ef7fa82874669852d63553e403aa5