Výsledky vyhledávání - "Changyin Shen"

Akademický článek

CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis

Autor: Zhimei Qiu, Yan Wang, Weiwei Liu, Chaofu Li, Ranzun Zhao, Xianping Long, Jidong Rong, Wengweng Deng, Changyin Shen, Jinson Yuan, Wengming Chen, Bei Shi

Publikováno v: Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)

Abstract Autophagy and apoptosis are involved in myocardial ischemia/reperfusion (I/R) injury. Research indicates that circular RNA HIPK3 (circHIPK3) is crucial to cell autophagy and apoptosis in various cancer types. However, the role of circHIPK3 i

Externí odkaz: https://doaj.org/article/0283c3d5037d44eda42575231de6ef2b

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Exosomal MiR-29a in Cardiomyocytes Induced by Angiotensin II Regulates Cardiac Microvascular Endothelial Cell Proliferation, Migration and Angiogenesis by Targeting VEGFA

Autor: Bei Shi, Yan Wang, Guangzhao Li, Zhimei Qiu, Chaofu Li, Ranzun Zhao, Yu Zhang, Changyin Shen, Weiwei Liu, Xianping Long, Shaowei Zhuang

Publikováno v: Current Gene Therapy. 22:331-341

Background: Exosomes released from cardiomyocytes (CMs) potentially play an important role in angiogenesis through microRNA (miR) delivery. Studies have reported an important role for miR-29a in regulating angiogenesis and pathological myocardial hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4452e3909616a3abc4f3dbb40090052d
https://doi.org/10.2174/1566523222666220303102951

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Effect of Telemedicine on Quality of Care in Patients with Coexisting Hypertension and Diabetes: A Systematic Review and Meta-Analysis

Autor: Wenhang Zhang, Wei Zhu, Huang Xiaoxia, Changyin Shen, Bo Cheng

Publikováno v: Telemedicine and e-Health. 27:603-614

Background: With the development of technology and the need for individualized and continuous support for patients with chronic conditions, telemedicine has been widely used. Despite the potential ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd777f5da319425f10770335f22b7eca
https://doi.org/10.1089/tmj.2020.0122

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CircUbe3a from M2 macrophage-derived small extracellular vesicles mediates myocardial fibrosis after acute myocardial infarction

Autor: Wei Zhang, Zhimei Qiu, Weiwei Liu, Changyin Shen, Junbo Ge, Zhenglong Wang, Chaofu Li, Bei Shi, Yan Wang, Ranzun Zhao

Publikováno v: Theranostics

Objective: This study aimed to explore the role of circular RNAs (circRNAs) in M2 macrophage (M2M)-derived small extracellular vesicles (SEVs) in myocardial fibrosis development. Methods: The regulatory role of M2M-derived extracellular vesicles (EVs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0666881bd90f8ed6afac3a14352969
https://doi.org/10.7150/thno.52843

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Development of a machine learning model to predict the risk of late cardiogenic shock in patients with ST-segment elevation myocardial infarction

Autor: Wei Zhang, Ranzun Zhao, Yan Wang, Wenwen Deng, Yi Ma, Bei Shi, Zhijiang Liu, Zhixun Bai, Ning Gu, Shan Hu, Zhenglong Wang, Changyin Shen

Publikováno v: Ann Transl Med

Background The in-hospital mortality of patients with ST-segment elevation myocardial infarction (STEMI) increases to more than 50% following a cardiogenic shock (CS) event. This study highlights the need to consider the risk of delayed calculation i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf726aa4f8e31f6eefcfc795d42c0d5f
https://pubmed.ncbi.nlm.nih.gov/34430603

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CircHIPK3 regulates the autophagy and apoptosis of hypoxia/reoxygenation-stimulated cardiomyocytes via the miR-20b-5p/ATG7 axis

Autor: Zhimei Qiu, Changyin Shen, Jinson Yuan, Ranzun Zhao, Bei Shi, Weiwei Liu, Yan Wang, Jidong Rong, Xianping Long, Chaofu Li, Wengming Chen, Wengweng Deng

Publikováno v: Cell Death Discovery
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)

Autophagy and apoptosis are involved in myocardial ischemia/reperfusion (I/R) injury. Research indicates that circular RNA HIPK3 (circHIPK3) is crucial to cell autophagy and apoptosis in various cancer types. However, the role of circHIPK3 in the reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04147fc7c6b4feb7dbf16fee57579ee
https://pubmed.ncbi.nlm.nih.gov/33824287

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Exosomal CircHIPK3 Released from Hypoxia-Induced Cardiomyocytes Regulates Cardiac Angiogenesis after Myocardial Infarction

Autor: Junbo Ge, Yan Wang, Ranzun Zhao, Zhenglong Wang, Bei Shi, Wenwen Deng, Chaofu Li, Wei Zhang, Changyin Shen, Jinson Yuan, Weiwei Liu

Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity

Exosomes play critical roles in mediating cell-to-cell communication by delivering noncoding RNAs (including miRNAs, lncRNAs, and circRNAs). Our previous study found that cardiomyocytes (CMs) subjected to hypoxia released circHIPK3-rich exosomes to r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148b15e76d793b725b513c5f8d508412
https://doaj.org/article/a809ce572b2c4f21b02c697d2686dad3

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[Expression of SDF-1/CXCR4 in acute infarct myocardium after implantation of bone marrow mesenchymal stem cells in rats]

Autor: Jin, Sheng, Yu, Xia, Guanxue, Xu, Ranzun, Zhao, Changyin, Shen, Dongmei, Wang, Zhijiang, Liu, Bei, Shi

Publikováno v: Zhonghua yi xue za zhi. 95(18)

To explore the role of stromal cell derived factor-1 (SDF-1)/CXCR4 axis in acute infarct myocardium after an implantation of bone marrow mesenchymal stem cells (MSCs) in rats.The animals were anesthetized by an intraperitoneal injection of pentobarbi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4a3777c4b6e8fe2760bf2b5b9e8cfda
https://pubmed.ncbi.nlm.nih.gov/26178362

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