Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Changxu Fan"'
Autor:
Changxu Fan, Xiaoyun Xing, Samuel J. H. Murphy, Jennifer Poursine-Laurent, Heather Schmidt, Bijal A. Parikh, Jeesang Yoon, Mayank N. K. Choudhary, Naresha Saligrama, Sytse J. Piersma, Wayne M. Yokoyama, Ting Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Comparative genomics has revealed the rapid expansion of multiple gene families involved in immunity. Members within each gene family often evolved distinct roles in immunity. However, less is known about the evolution of their epigenome and
Externí odkaz:
https://doaj.org/article/2e1544ec47b24a0fa0e54cc35c3f6b85
Autor:
Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, Wayne M Yokoyama
Publikováno v:
eLife, Vol 11 (2022)
BTB domain And CNC Homolog 2 (Bach2) is a transcription repressor that actively participates in T and B lymphocyte development, but it is unknown if Bach2 is also involved in the development of innate immune cells, such as natural killer (NK) cells.
Externí odkaz:
https://doaj.org/article/4803a607778c48e2a158ffe3d291b821
Autor:
Seongmi K. Russell, Jessica K. Harrison, Benjamin S. Olson, Hyung Joo Lee, Valerie P. O’Brien, Xiaoyun Xing, Jonathan Livny, Lu Yu, Elisha D. O. Roberson, Rajdeep Bomjan, Changxu Fan, Marina Sha, Shady Estfanous, Amal O. Amer, Marco Colonna, Thaddeus S. Stappenbeck, Ting Wang, Thomas J. Hannan, Scott J. Hultgren
Publikováno v:
Nature Microbiology. 8:875-888
Previous urinary tract infections (UTIs) can predispose one to future infections; however, the underlying mechanisms affecting recurrence are poorly understood. We previously found that UTIs in mice cause differential bladder epithelial (urothelial)
Autor:
Nakul M. Shah, H. Josh Jang, Yonghao Liang, Ju Heon Maeng, Shin-Cheng Tzeng, Angela Wu, Noah L. Basri, Xuan Qu, Changxu Fan, Amy Li, Benjamin Katz, Daofeng Li, Xiaoyun Xing, Bradley S. Evans, Ting Wang
Publikováno v:
Nature Genetics. 55:631-639
Autor:
Ulezko Antonova, Alina, Lonardi, Silvia, Monti, Matilde, Missale, Francesco, Changxu Fan, Coates, Matthew L., Bugatti, Mattia, Jaeger, Natalia, Fernandes Rodrigues, Patrick, Brioschi, Simone, Trsan, Tihana, Fachi, José L., Khai M. Nguyen, Nunley, Ryan M., Moratto, Daniele, Zini, Stefania, Lingjia Kong, Deguine, Jacques, Peeples, Mark E., Xavier, Ramnik J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 12/26/2023, Vol. 120 Issue 52, p1-11, 35p
Autor:
Maria Cimpean, Molly P. Keppel, Anastasiia Gainullina, Changxu Fan, Nathan C. Schedler, Amanda Swain, Ana Kolicheski, Hannah Shapiro, Howard A. Young, Ting Wang, Maxim N. Artyomov, Megan A. Cooper
Publikováno v:
bioRxiv
Natural killer (NK) effector functions can be triggered by inflammatory cytokines and engagement of activating receptors. NK cell production of IFN-γ, an important immunoregulatory cytokine, exhibits activation-specific IFN-γ regulation. Resting mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe4ac945029f4f901856c17641d7365
https://europepmc.org/articles/PMC10168240/
https://europepmc.org/articles/PMC10168240/
Autor:
Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, Wayne M Yokoyama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03907c44d1f50c98eb455ecda44f3ae6
https://doi.org/10.7554/elife.77294.sa2
https://doi.org/10.7554/elife.77294.sa2
Autor:
Daofeng Li, Deepak Purushotham, Jessica K Harrison, Silas Hsu, Xiaoyu Zhuo, Changxu Fan, Shane Liu, Vincent Xu, Samuel Chen, Jason Xu, Shinyi Ouyang, Angela S Wu, Ting Wang
Publikováno v:
Nucleic acids research.
WashU Epigenome Browser (https://epigenomegateway.wustl.edu/browser/) is a web-based genomic data exploration tool that provides visualization, integration, and analysis of epigenomic datasets. The newly renovated user interface and functions have en
Autor:
Xiao Huang, Julia A. Belk, Yanyan Qi, Marco Colonna, Jing Chen, Nghi Ly, Changxu Fan, Ting Wang, Raki Sudan, Martin Guilliams, Pritesh Desai, Prachi Bagadia, Ansuman T. Satpathy, Stephen T. Ferris, Theresa L. Murphy, Mayank N. K. Choudhary, Yu Xia, Takeshi Egawa, Michael S. Diamond, Kenneth M. Murphy, Sunkyung Kim, Tiantian Liu, Quanming Shi
Publikováno v:
Immunity
The transcriptional repressor ZEB2 regulates development of many cell fates among somatic, neural and hematopoietic lineages, but the basis for its requirement in these diverse lineages is unclear. Here, we identified a 400 basepair (bp) region locat
Autor:
Arnold R. Kriegstein, Ming Hu, Ugomma C. Eze, Michael Song, Changxu Fan, Ian Jones, Ivan Juric, Lenka Maliskova, Yin Shen, Mayank N. K. Choudhary, Ting Wang, Jerry Lee, Bingkun Li, Seth Bergenholtz, Mark-Phillip Pebworth, Jia Wen, Yun Li, Armen Abnousi, Xiekui Cui, Weifang Liu, Alex A. Pollen, Jonathan D. Rosen, Xiaoyu Yang
Publikováno v:
Nature, vol 587, iss 7835
Nature
Nature
Lineage-specific epigenomic changes during human corticogenesis have remained elusive due to challenges with sample availability and tissue heterogeneity. For example, previous studies used single-cell RNA sequencing to identify at least nine major c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62a644c262ff83307505111efd951970
https://escholarship.org/uc/item/9x4848qd
https://escholarship.org/uc/item/9x4848qd