Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Changxiu Qu"'
Autor:
Xiu Li, Xuan Zhang, Xin Wen, Daolai Zhang, Changxiu Qu, Xinyi Miao, Wenkai Zhang, Ru Zhang, Guibing Liu, Peng Xiao, Jin-Peng Sun, Weimin Gong
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113893- (2024)
Summary: Prostaglandin F2α (PGF2α) and thromboxane A2 (TXA2) are endogenous arachidonic acid metabolites, modulating diverse physiological processes including inflammation and cardiovascular homeostasis through activating PGF2α receptor (FP) and T
Externí odkaz:
https://doaj.org/article/c4f758df63c04704be776001aedbcc06
Autor:
Zhongliang Zhu, Peng Xiao, Jin-Peng Sun, Zijian Li, Changxiu Qu, Lulu Guo, Lei Liu, Xu Yan, Xiao Yu, Yu Li, Fan Yang, Qun Liu, Guo-Xing Fang, Xu Chen, Yunfei Xu, Chao Zhang, Ning Gao, Guopeng Wang, Jia Wang, Jiuyao Zhou
Publikováno v:
Nature. 600:164-169
In the clades of animals that diverged from the bony fish, a group of Mas-related G-protein-coupled receptors (MRGPRs) evolved that have an active role in itch and allergic signals1,2. As an MRGPR, MRGPRX2 is known to sense basic secretagogues (agent
Autor:
Zhongliang Zhu, Xiaohong Liu, Mengyi Yang, Chunlai Chen, Yirong Yao, Chao Chen, Ming-Jie Han, Changxiu Qu, Dawei Zhang, Fan Yang, Qing-tao He, Yuchuan Wang, Jin-Peng Sun, Jiangyun Wang, Cheng Hu, Xuzhen Guo, Kong-kai Zhu
Publikováno v:
Chemical Science
Single-molecule Förster resonance energy transfer (smFRET) is a powerful tool for investigating the dynamic properties of biomacromolecules. However, the success of protein smFRET relies on the precise and efficient labeling of two or more fluoropho
Autor:
Qingya Shen, Xiaona Tao, Ya-Ni Zhong, Zijian Li, Xin Wen, Caiping Tian, Huibing Zhang, Jin-Peng Sun, Fan Yang, Fan Yi, H. Eric Xu, Xiao Yu, Yi Jiang, Peng Xiao, Guang-Yu Wang, Yan Zhang, Wen-Tao An, Shaolong Li, Changxiu Qu, Zhao Yang, Chunyou Mao, Ru-Jia Zhao, Yu-Qi Ping, Jing Yang, Dan-Dan Shen
Publikováno v:
Nature. 589:620-626
Adhesion G-protein-coupled receptors (GPCRs) are a major family of GPCRs, but limited knowledge of their ligand regulation or structure is available1-3. Here we report that glucocorticoid stress hormones activate adhesion G-protein-coupled receptor G
Autor:
Jing-Yu Lin, Changxiu Qu, Qi Liu, Changwen Jin, Peng Sun, Sheng-chao Guo, Xiaoyan Wang, Xiaogang Niu, Zhao Yang, Zhen Xu, Zijian Li, Peng Xiao, Kunhong Xiao, Zhongliang Zhu, Fahui Li, Qing-tao He, Xin Chen, Zheng Gong, Ke Ruan, Jiangyun Wang, Shao-le Song, Jin-Peng Sun, Kong-kai Zhu, Feng Zhang, Qian-wen Wang, Fan Yang, Zhao-ya Yang, Wei Kong, Xiao Yu, Xiao-xuan Lyu, Ming-Jie Han, Shen-Ming Huang, Alem W. Kahsai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Characterization of the dynamic conformational changes in membrane protein signaling complexes by nuclear magnetic resonance (NMR) spectroscopy remains challenging. Here we report the site-specific incorporation of 4-trimethylsilyl phenylalanine (TMS
Autor:
Fan Yang, Jiangyun Wang, Fahui Li, Jin-Peng Sun, Qi Liu, Ming-Jie Han, Wei Kong, Yingli Jia, Xiao Yu, Changxiu Qu, Shen-Ming Huang, Bai-Yang Cai, Qing-tao He
Publikováno v:
Analytical Chemistry. 91:14936-14942
Forster resonance energy transfer (FRET) is a well-established method for studying macromolecular interactions and conformational changes within proteins. Such a method normally uses fluorescent proteins or chemical-labeling methods which are often o
Autor:
Kiae Kim, Rui-Rui Li, Vsevolod V. Gurevich, Ka Young Chung, Fan Yang, Donghee Ham, Ji Young Park, Changxiu Qu, Min Woo Yun, Jin-Peng Sun, Tina M. Iverson, Qing-Tao He
Publikováno v:
Proc Natl Acad Sci U S A
Arrestins were initially identified for their role in homologous desensitization and internalization of G protein-coupled receptors. Receptor-bound arrestins also initiate signaling by interacting with other signaling proteins. Arrestins scaffold MAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9e0fc3184ac3b6fefc5d9feb60e2c6
https://europepmc.org/articles/PMC8449410/
https://europepmc.org/articles/PMC8449410/
Autor:
Ya-Ni Zhong, Xiaona Tao, Xu Yan, Jin-Peng Sun, Qingya Shen, Xiao Yu, Changxiu Qu, Dan-Dan Shen, Ying Guan, Chao Zhang, Chunyou Mao, Peng-Ju Zhang, Ru-Jia Zhao, Peng Xiao, Guige Hou, Yan Zhang, Guihua Hou, Junyan He, Fan Yang, Huibing Zhang, Renjie Chai, You-Fei Guan, Zijian Li
Publikováno v:
Science Advances. 7
Selective modulation of the heterotrimeric G protein α S subunit-coupled prostaglandin E2 (PGE2) receptor EP2 subtype is a promising therapeutic strategy for osteoporosis, ocular hypertension, neurodegenerative diseases, and cardiovascular disorders
Autor:
Changxiu, Qu, Chunyou, Mao, Peng, Xiao, Qingya, Shen, Ya-Ni, Zhong, Fan, Yang, Dan-Dan, Shen, Xiaona, Tao, Huibing, Zhang, Xu, Yan, Ru-Jia, Zhao, Junyan, He, Ying, Guan, Chao, Zhang, Guihua, Hou, Peng-Ju, Zhang, Guige, Hou, Zijian, Li, Xiao, Yu, Ren-Jie, Chai, You-Fei, Guan, Jin-Peng, Sun, Yan, Zhang
Publikováno v:
Science advances. 7(14)
Selective modulation of the heterotrimeric G protein α S subunit-coupled prostaglandin E
Autor:
Yu-Qi, Ping, Chunyou, Mao, Peng, Xiao, Ru-Jia, Zhao, Yi, Jiang, Zhao, Yang, Wen-Tao, An, Dan-Dan, Shen, Fan, Yang, Huibing, Zhang, Changxiu, Qu, Qingya, Shen, Caiping, Tian, Zi-Jian, Li, Shaolong, Li, Guang-Yu, Wang, Xiaona, Tao, Xin, Wen, Ya-Ni, Zhong, Jing, Yang, Fan, Yi, Xiao, Yu, H Eric, Xu, Yan, Zhang, Jin-Peng, Sun
Publikováno v:
Nature. 589(7843)
Adhesion G-protein-coupled receptors (GPCRs) are a major family of GPCRs, but limited knowledge of their ligand regulation or structure is available