Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Changwen Jin"'
Autor:
Xiaoxue Huang, Hao Li, Changwen Jin, Bowen Huang, Xinhang Li, Yiping Zheng, Xianglong Meng, Zhiyong Gao
Publikováno v:
Journal of Materials Research and Technology, Vol 30, Iss , Pp 8240-8247 (2024)
Compositions, surface morphologies and mechanical properties of a novel designed TiNi/Ag bi-layer film grown by DC magnetron sputtering at various processes have been investigated. Ar pressure and sputtering power had significant effects on quality a
Externí odkaz:
https://doaj.org/article/5fd9e3ca847041cfb4388bc8e8f9856e
Autor:
Xu Dong, Lulu Yu, Qiang Zhang, Ju Yang, Zhou Gong, Xiaogang Niu, Hongwei Li, Xu Zhang, Maili Liu, Changwen Jin, Yunfei Hu
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The WRKY transcription factors play essential roles in a variety of plant signaling pathways associated with biotic and abiotic stress response. The transcriptional activity of many WRKY members are regulated by a class of intrinsically diso
Externí odkaz:
https://doaj.org/article/064a5c6c75ae4f60a9cb6cb1824dfe9d
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract β-Arrestins (βarrs) are functionally versatile proteins that play critical roles in the G-protein-coupled receptor (GPCR) signaling pathways. While it is well established that the phosphorylated receptor tail plays a central role in βarr
Externí odkaz:
https://doaj.org/article/a9214942e76246dbaab6dadef4a76603
Autor:
Jie Heng, Yunfei Hu, Guillermo Pérez-Hernández, Asuka Inoue, Jiawei Zhao, Xiuyan Ma, Xiaoou Sun, Kouki Kawakami, Tatsuya Ikuta, Jienv Ding, Yujie Yang, Lujia Zhang, Sijia Peng, Xiaogang Niu, Hongwei Li, Ramon Guixà-González, Changwen Jin, Peter W. Hildebrand, Chunlai Chen, Brian K. Kobilka
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Advances in structural biology have provided important mechanistic insights into signaling by the transmembrane core of G-protein coupled receptors (GPCRs); however, much less is known about intrinsically disordered regions such as the carbo
Externí odkaz:
https://doaj.org/article/6adf05da047844e19288363de84f8e23
Autor:
Jun Xu, Qinggong Wang, Harald Hübner, Yunfei Hu, Xiaogang Niu, Haoqing Wang, Shoji Maeda, Asuka Inoue, Yuyong Tao, Peter Gmeiner, Yang Du, Changwen Jin, Brian K. Kobilka
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Here, using cryo-electron microscopy and solution NMR, the authors reveal the structural and dynamic mechanisms underlying the signaling versatility of a muscarinic receptor regulated by orthosteric and allosteric ligands.
Externí odkaz:
https://doaj.org/article/2a8a4fc6bad2451e913c4050e4dba574
Autor:
Yunfei Hu, Changwen Jin
Publikováno v:
Magnetic Resonance Letters, Vol 2, Iss 3, Pp 139-146 (2022)
G-protein-coupled receptors (GPCRs) mediate a wide range of cellular responses to various ligands or stimuli, and are the most important drug targets associated with human diseases. While major advances in GPCR structural biology have greatly deepene
Externí odkaz:
https://doaj.org/article/eb05add75a164a05b65cad7a399f7e3c
Structural studies of phosphorylation-dependent interactions between the V2R receptor and arrestin-2
Autor:
Qing-Tao He, Peng Xiao, Shen-Ming Huang, Ying-Li Jia, Zhong-Liang Zhu, Jing-Yu Lin, Fan Yang, Xiao-Na Tao, Ru-Jia Zhao, Feng-Yuan Gao, Xiao-Gang Niu, Kun-Hong Xiao, Jiangyun Wang, Changwen Jin, Jin-Peng Sun, Xiao Yu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The interaction between a GPCR, such as the vasopressin receptor-2 (V2R), and arrestin depends on the receptors’ phosphorylation pattern. Here authors use FRET and NMR to analyze the phosphorylation patterns of the V2R-arrestin complex and show tha
Externí odkaz:
https://doaj.org/article/5ffe1d9ce0c04791b889a4c6d158110f
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract The thioredoxin (Trx)-coupled arsenate reductase (ArsC) is a family of enzymes that catalyzes the reduction of arsenate to arsenite in the arsenic detoxification pathway. The catalytic cycle involves a series of relayed intramolecular and in
Externí odkaz:
https://doaj.org/article/f107f36c806848fe9ba43bb176dbaf44
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103936 (2014)
Flavodoxins are a family of small FMN-binding proteins that commonly exist in prokaryotes. They utilize a non-covalently bound FMN molecule to act as the redox center during the electron transfer processes in various important biological pathways. Al
Externí odkaz:
https://doaj.org/article/39cd72b352164ace94dfb36720694b4b
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103157 (2014)
Many proteins are transported across lipid membranes by protein translocation systems in living cells. The twin-arginine transport (Tat) system identified in bacteria and plant chloroplasts is a unique system that transports proteins across membranes
Externí odkaz:
https://doaj.org/article/79b906ea652f4b75b6583799fa294503