Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Changqin Hu"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The conditions and mechanisms leading to stability differences between ceftriaxone sodium products were examined to ensure drug quality and efficacy. We used a combination of powder X-ray diffraction and thermogravimetric analysis to examine
Externí odkaz:
https://doaj.org/article/87a642c00eb64122b92852928c11e610
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Enteric tablet coating thickness is a critical quality attribute of the coating process that can affect dissolution behavior in vitro as well as release in vivo. Raman mapping offers unique advantages in analyzing the distribution of active pharmaceu
Externí odkaz:
https://doaj.org/article/5a29f23bf74649c4a7e949df5d28cab9
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 12, Iss 3, Pp 481-488 (2022)
Penicillins are one type of the most important antibiotics used in the clinic. Control of drug impurity profiles is an important part of ensuring drug safety. This is particularly important in penicillins where polymerization can lead to polymers as
Externí odkaz:
https://doaj.org/article/0b196389c5d943e79b49dcea518fcb13
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 11, Iss 5, Pp 588-595 (2021)
From a regulatory perspective, drug quality consistency evaluation must concern different processes used for the same drug. In this study, an assessment strategy based on quality by design (QbD) was developed for population pharmaceutical quality eva
Externí odkaz:
https://doaj.org/article/c567e1d50f234f54a3197d9a9a9d88bd
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 243, Iss , Pp 113981- (2022)
Statins are prescribed widely as lipid-lowering agents. However, statins are associated with an increased harmful risk on public health and the ecosystem. Little is known about statins’ toxicity on biological development and the underlying molecula
Externí odkaz:
https://doaj.org/article/0e12f3955cb3470c9493180a6a31e429
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 229, Iss , Pp 113106- (2022)
Antibiotics have emerged as a well-known representative of pharmaceuticals and personal care products (PPCPs) by causing public health and environmental problems due to their potential toxicity. β-lactams are the most commonly used antibiotics in th
Externí odkaz:
https://doaj.org/article/a817752c19154eb596457bd84a8551ed
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Calcium carbonate which is extracted from the Earth in combination with other mineral impurities, is largely used in preparations for pediatric supplements. Elemental impurities in drug products pose toxicological concerns without therapeutic benefit
Externí odkaz:
https://doaj.org/article/935bbe19f81e434eb23e4f901bf31244
Autor:
Lingqiao Li, Xipeng Pan, Wenli Chen, Manman Wei, Yanchun Feng, Lihui Yin, Changqin Hu, Huihua Yang
Publikováno v:
Journal of Innovative Optical Health Sciences, Vol 13, Iss 4, Pp 2050016-1-2050016-12 (2020)
Near infrared (NIR) spectrum analysis technology has outstanding advantages such as rapid, nondestructive, pollution-free, and is widely used in food, pharmaceutical, petrochemical, agricultural products production and testing industries. Convolution
Externí odkaz:
https://doaj.org/article/8afee43acc834b999334053e7a622898
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Cephalosporins are beta-lactam antibiotics that are widely used in China. Five generations of cephalosporins have been introduced in clinical practice to date; moreover, some new candidates are also undergoing clinical evaluations. To improve the suc
Externí odkaz:
https://doaj.org/article/6808526851bc4380899cbaae1df950cf
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Most third- and fourth-generation cephalosporins, such as cefotaxime, cefmenoxime, cefepime, and cefpirome, contain an aminothiazoyl ring at the C-7 position. Drug impurity, which may be produced either during synthesis or upon degradation, can induc
Externí odkaz:
https://doaj.org/article/60dd428f8feb457a83450b082ca73b70