Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Changqiang Ke"'
Autor:
Qun Zhou, Yatong Zhao, Changqiang Ke, Haojun Wang, Sheng Gao, Hui Li, Yan Zhang, Yang Ye, Yunzi Luo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The multifunctional proteins of class 2 CRISPR systems such as Cas9, have been employed to activate cryptic biosynthetic gene clusters (BGCs) in Streptomyces, which represent a large and hidden reservoir of natural products. However, such ap
Externí odkaz:
https://doaj.org/article/9cb30889cebe4250b09911efaeda39ed
Autor:
Haixia Su, Sheng Yao, Wenfeng Zhao, Yumin Zhang, Jia Liu, Qiang Shao, Qingxing Wang, Minjun Li, Hang Xie, Weijuan Shang, Changqiang Ke, Lu Feng, Xiangrui Jiang, Jingshan Shen, Gengfu Xiao, Hualiang Jiang, Leike Zhang, Yang Ye, Yechun Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
SARS-CoV-2 3CL protease (3CLpro) is essential for coronavirus replication and of great interest as an antiviral drug target. Here, the authors show that the naturally occurring flavonoid myricetin is a non-peptidomimetic and covalent inhibitor of 3CL
Externí odkaz:
https://doaj.org/article/ff68234682c746f3aa209aef3785fbf8
Publikováno v:
Molecules, Vol 28, Iss 10, p 4254 (2023)
Artemisia divaricate belongs to the Artemisia genus of the family of Compositae, a sort of perennial herb endemic in most regions of China. For the first time, a phytochemical investigation was carried out on the whole plant of Artemisia divaricate,
Externí odkaz:
https://doaj.org/article/5a1808c9fafa4c488b803ea44366f8f2
Chantriolides F–P, Highly Oxidized Withanolides with Hepatoprotective Activity from Tacca chantrieri
Autor:
Yue Yang, Fei Zhou, Min Wang, Mukhammadrizo Turanazarov, Xiao-Rong Wang, Changqiang Ke, Sheng Yao, Ligen Lin, Chunping Tang, Yang Ye
Publikováno v:
Molecules, Vol 27, Iss 23, p 8197 (2022)
Eleven highly oxidized withanolides, chantriolides F–P (1–11), together with six known analogues (12–17), were isolated from the rhizomes of Tacca chantrieri. Their structures were established on the basis of comprehensive spectroscopic data an
Externí odkaz:
https://doaj.org/article/55f742b34b2c4680b972e23ac3b2e761
Autor:
Zhuo LI, Hang XIE, Chunping TANG, Lu FENG, Changqiang KE, Yechun XU, Haixia SU, Sheng YAO, Yang YE
Publikováno v:
Chinese Journal of Natural Medicines. 21:65-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df481b0fb3abcb1cfa1a26d08dc570b
https://doi.org/10.1016/s1875-5364(23)60386-3
https://doi.org/10.1016/s1875-5364(23)60386-3
Autor:
Dafu Zhu, Haixia Su, Changqiang Ke, Chunping Tang, Matthias Witt, Ronald J. Quinn, Yechun Xu, Jia Liu, Yang Ye
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis
Graphical Abstract ga1 A native MS-based affinity-selection method was developed to screen compounds that target SARS-CoV-2 3CLpro from TCMs crude extracts.
The 3C-like protease (3CLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-C
The 3C-like protease (3CLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5899a91008b9f92133ec39771a3b8191
http://europepmc.org/articles/PMC8670146
http://europepmc.org/articles/PMC8670146
Publikováno v:
Records of Natural Products. 2014, Vol. 8 Issue 4, p317-322. 6p. 3 Black and White Photographs, 1 Chart.
Autor:
F. Gillardon, Walter Bolek, Changqiang Ke, Olivier Potterat, Klaus Wagner, Carsten H. Puder, Yang Ye
Publikováno v:
ChemInform. 36
A new carbazole alkaloid, named clausine Z, has been isolated from the stems and leaves of Clausena excavata Burm. (Rutaceae). Its structure was established by spectroscopic methods. The compound exhibits inhibitory activity against cyclin-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669c550d13548efdf4fbad5222449723
https://doi.org/10.1002/chin.200550185
https://doi.org/10.1002/chin.200550185
Publikováno v:
Planta Medica; 2017, Vol. 83 Issue 17, p1361-1367, 7p
Publikováno v:
Records of Natural Products. 2015, Vol. 9 Issue 2, p267-270. 4p. 2 Charts, 1 Graph.