Nanoscale Porphyrin Metal-Organic Frameworks Deliver siRNA for Alleviating Early Pulmonary Fibrosis in Acute Lung Injury

Autor: Changmei Weng, Guanhua Li, Dongdong Zhang, Zhaoxia Duan, Kuijun Chen, Jieyuan Zhang, Tao Li, Jianmin Wang

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)

Acute lung injury (ALI) has high mortality and still lacks novel and efficient therapies. Zinc finger E-box binding homeobox 1 and 2 (ZEB1/2) are highly expressed in the early stage of ALI and are positively correlated with the progression of pulmona

Externí odkaz: https://doaj.org/article/20d403f1175f4955afd26a365ef72c98

Intra-articular injection of anti-inflammatory peptide-loaded glycol chitosan/fucoidan nanogels to inhibit inflammation and attenuate osteoarthritis progression

Autor: Yang Huang, Changmei Weng, Shuo Meng, Tao Li, Cheng Chen, Pingju Liu, Rong Li, Liu Yang, Xiaoyuan Gong, Junjun Yang

Publikováno v: International journal of biological macromolecules. 170

Glycol chitosan/fucoidan nanogels loaded with anti-inflammatory peptide KAFAK (GC/Fu@KAFAK NGs) were fabricated based on the electrostatic interaction and genipin cross-linking methods. The prepared NGs had an average size of 286.3 ± 5.0 nm and posi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e8aaeca0dca648a32187fb6e614e9f
https://pubmed.ncbi.nlm.nih.gov/33359610

Regional hypothermia attenuates secondary-injury caused by time-out application of tourniquets following limb fragments injury combined with hemorrhagic shock

Autor: Liangchao Zhang, Tao Li, Xinan Lai, Changmei Weng, Jianmin Wang, Kai Lan

Publikováno v: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 27, Iss 1, Pp 1-11 (2019)

BackgroundTourniquet is the most widely used and effective first-aid equipment for controlling hemorrhage of injured limb in battlefield. However, time-out application of tourniquets leads to ischemic-necrosis of skeletal muscles and ischemia-reperfu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b6b217c86414efff2fa7dfc87dfa84
http://europepmc.org/articles/PMC6873525

The effects of the M2a macrophage-induced axonal regeneration of neurons by arginase 1.

Autor: Jieyuan Zhang, Yue Li, Zhaoxia Duan, Jianyi Kang, Kuijun Chen, Guanhua Li, Changmei Weng, Dongdong Zhang, Lu Zhang, Jianmin Wang, Bingcang Li

Publikováno v: Bioscience Reports; Feb2020, Vol. 40 Issue 2, p1-11, 11p