Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Changlu, Liu"'
Publikováno v:
Shipin Kexue, Vol 45, Iss 17, Pp 52-62 (2024)
This study investigated high-throughput screening of inhibitors for the key enzyme CitE in the synthesis of red yeast citrinin through computer simulation. First, Alphafold 2 was used to build the homology model of CitE. and it was aligned with simil
Externí odkaz:
https://doaj.org/article/28f7dd4be04c447593dedf191f41e58b
Publikováno v:
Asian Journal of Surgery, Vol 47, Iss 10, Pp 4341-4342 (2024)
Externí odkaz:
https://doaj.org/article/7f88835b8e7e46f7923bc410e122fa5d
Autor:
Yi Liu, Jichun Ma, Renee L. DesJarlais, Rebecca Hagan, Jason Rech, Changlu Liu, Robyn Miller, Jeffrey Schoellerman, Jinquan Luo, Michael Letavic, Bruce Grasberger, Michael P. Maher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Acid-sensing ion channels (ASICs) are proton-gated cation channels widely expressed in the nervous system. ASIC gating is modulated by divalent cations as well as small molecules; however, the molecular determinants of gating modulation by d
Externí odkaz:
https://doaj.org/article/7532453b22314d01ada9b275f434a0b8
Publikováno v:
Zhongguo dizhi zaihai yu fangzhi xuebao, Vol 34, Iss 3, Pp 58-68 (2023)
Due to the heavy rainfall, from February 26th to 28th 2021, the Moli landslide in Guoye Town, Zhouqu County, experienced creeping deformation with the development of slope cracks and obnious signs of deformation. A total of of 92 households with 402
Externí odkaz:
https://doaj.org/article/9e1e1ad6447945dd9f683670042941e1
Autor:
Yi Liu, Jichun Ma, Renee L. DesJarlais, Rebecca Hagan, Jason Rech, David Lin, Changlu Liu, Robyn Miller, Jeffrey Schoellerman, Jinquan Luo, Michael Letavic, Bruce Grasberger, Michael Maher
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Liu et al study the molecular and structural mechanism of the modulation of ASIC1 channel gating using functional, crystallographic, computational and mutational approaches. They identify small molecules that allosterically stabilize the closed state
Externí odkaz:
https://doaj.org/article/cd6928ca293c4d9a8cd20517994d727a
Autor:
Ling Gong, Gang Liu, Honglan Zhu, Caihong Li, Pengmei Li, Changlu Liu, Hongbo Tang, Kaifeng Wu, Jie Wu, Daishun Liu, Xiaoping Tang
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Epithelial-mesenchymal transition (EMT) is a key process in the onset and development of idiopathic pulmonary fibrosis (IPF) with unclear mechanisms. Our previous studies found that bleomycin and tunicamycin could induce ER stress
Externí odkaz:
https://doaj.org/article/a63f7331f7e2494cb0c62ffc07cd9f28
Publikováno v:
Journal of the Pakistan Medical Association, Vol 71, Iss 4 (2021)
Objective: A number of recent clinical studies have identified a relationship between elevated expressions of 14-3-3 and poorer patient prognosis in the context of several cancers. The present meta-analysis was therefore conducted to gain an enhanced
Externí odkaz:
https://doaj.org/article/44840a54c3c44d149d88fc14334bd468
Autor:
Belinda Liu, Grace Lee, Jiejun Wu, Janise Deming, Chester Kuei, Anthony Harrington, Lien Wang, Jennifer Towne, Timothy Lovenberg, Changlu Liu, Siquan Sun
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0222685 (2020)
Unlike closely related GPCRs, protease-activated receptors (PAR1, PAR2, PAR3, and PAR4) have a predicted signal peptide at their N-terminus, which is encoded by a separate exon, suggesting that the signal peptides of PARs may serve an important and u
Externí odkaz:
https://doaj.org/article/e8b1bd642b6a478a900fecce70696e92
Publikováno v:
Environmental Science and Pollution Research. 30:6245-6261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c2ffc7feb5f8b01250b328d0351fc85
https://doi.org/10.1007/s11356-022-22590-z
https://doi.org/10.1007/s11356-022-22590-z
Autor:
Lien Wang, Grace Lee, Chester Kuei, Xiang Yao, Anthony Harrington, Pascal Bonaventure, Timothy W. Lovenberg, Changlu Liu
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
GPR139, a Gq-coupled receptor that is activated by the essential amino acids L-tryptophan and L-phenylalanine, is predominantly expressed in the brain and pituitary. The physiological function of GPR139 remains elusive despite the availability of pha
Externí odkaz:
https://doaj.org/article/e449a4d4996f49609c3f78519cc16389