Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Changlian Zhu"'
Autor:
Mengmeng Du, Shengnan Wu, Yongxing Chen, Shuxian Yuan, Shijie Dong, Huizhen Wang, Haiyan Wei, Changlian Zhu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Methylmalonic acidemia (MMA) is the most common inborn organic acidemia, presenting multisystemic complications. Uric acid may have neurotoxic or neuroprotective effects due to its antioxidant or pro-inflammatory properties; however, its rol
Externí odkaz:
https://doaj.org/article/1b932f73bcfd416b93e8eb86a7123957
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-9 (2024)
Abstract Neurodegenerative diseases pose a significant health burden globally, with limited treatment options available. Among the various cell types involved in the pathogenesis of these disorders, microglia, the resident immune cells of the central
Externí odkaz:
https://doaj.org/article/d55e32784f37458694afecbf71f262e1
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 4, Pp 101357- (2024)
Pediatric monogenetic diseases encompass a spectrum of debilitating neurological disorders that affect infants and children, often resulting in profound cognitive and motor impairments. Gene replacement therapy holds immense promise in addressing the
Externí odkaz:
https://doaj.org/article/e28afc2dadbe4c0e8f5fe8284f513cdd
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 7, Pp 1499-1508 (2024)
Cerebral palsy is a diagnostic term utilized to describe a group of permanent disorders affecting movement and posture. Patients with cerebral palsy are often only capable of limited activity, resulting from non-progressive disturbances in the fetal
Externí odkaz:
https://doaj.org/article/97c32f65d5494372aeabff55d1f116c7
Autor:
Juan Song, Yuyang Yue, Huiqing Sun, Ping Cheng, Falin Xu, Bingbing Li, Kenan Li, Changlian Zhu
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract Background Leukomalacia is a serious form of neonatal brain injury that often leads to neurodevelopmental impairment, and studies on neonatal leukomalacia and its long-term outcomes are lacking. The aim of this study was to analyze the clini
Externí odkaz:
https://doaj.org/article/f8c9dabe20374d71b0a9c097e6854990
Autor:
Qian Li, Man Wang, Yue Zhang, Yubing Li, Xianfen Zhang, Haowei Li, Ying Peng, Changlian Zhu, Pengyuan Zheng, Shaolong Yang, Jiang Li, Jiafu Lin, Rong He, Hongmei Zhang, Huoxiang Zhou
Publikováno v:
Journal of Functional Foods, Vol 112, Iss , Pp 105928- (2024)
Pectic oligosaccharides have been proposed as a novel prebiotic to prevent obesity and associated with metabolic disorders by regulating gut microbiota, but their various probiotic functions in the gut depended on their complex and heterogeneous suga
Externí odkaz:
https://doaj.org/article/4c278e10947e4095bb7f3ab7c4cd984b
Autor:
Wei Han, Eva-Maria Meißner, Stefanie Neunteibl, Madeline Günther, Jörg Kahnt, Amalia Dolga, Cuicui Xie, Nikolaus Plesnila, Changlian Zhu, Klas Blomgren, Carsten Culmsee
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-11 (2023)
Summary Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs
Externí odkaz:
https://doaj.org/article/83f1e396304f48eb9d728d896a1d6a89
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveWe investigated the association between bronchopulmonary dysplasia (BPD) and 3 years death or neurodevelopmental impairment (NDI) in very preterm infants without severe brain injury.MethodOur prospective cohort study recruited preterm infant
Externí odkaz:
https://doaj.org/article/16709a2264cd4d6d8aba0d9927c4c3d6
Publikováno v:
European Radiology Experimental, Vol 6, Iss 1, Pp 1-10 (2022)
Abstract Background The cerebellum is involved in hyperactivity, fear, and anxiety disorders that could be induced by whole-brain irradiation (WBI). However, whether cerebellar irradiation alone (CIA) could induce these disorders is unknown. We inves
Externí odkaz:
https://doaj.org/article/177c882aa22945758314f966d8f887da
Autor:
Yimeng Qiao, Yangong Wang, Yiran Xu, Jin Zhang, Yu Su, Ye Cheng, Dan Bi, Juan Song, Lei Xia, Ming Li, Xiaoli Zhang, Dengna Zhu, Ting Wang, Jian Ding, Xiaoyang Wang, Changlian Zhu, Qinghe Xing
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background Cerebral palsy (CP), the most common physical disability of childhood, is a nonprogressive movement disorder syndrome. Eighty percent of cases are considered idiopathic without a clear cause. Evidence has shown that cytokine abnor
Externí odkaz:
https://doaj.org/article/85bf702066b04fb1bed592e17c8f35b3