Výsledky vyhledávání - "Changjiang Zeng"

Uninfluenced alpha-fetoprotein and treatment of liver primary carcinoma by lobaplatin in combination with 5-fluorouracil and doxorubicin via chemoembolization and transarterial chemoembolization

Autor: Qing Yang, Changjiang Zeng, Weibin Li, Yongpin Chen, Liang Chen

Publikováno v: Cellular and Molecular Biology. 66:48-51

Alpha-fetoprotein (AFP) is a protein encoded by the AFP gene and normally produced by the fetus. The purpose of this study is to investigate the efficacy of lobaplatin in combination with 5-fluorouracil (5-FU) and doxorubicin on AFP and treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5da5b68bff7da971f6f1ee16b91daf0
https://doi.org/10.14715/cmb/2020.66.3.7

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A Computational Framework to Identify Transcriptional and Network Differences between Hepatocellular Carcinoma and Normal Liver Tissue and Their Applications in Repositioning Drugs

Autor: Zuxiang Zheng, Aimin Hu, Xinhong Zhou, Zheng Wei, Changjiang Zeng, Jieming Yi, Bichao Luo

Publikováno v: BioMed Research International, Vol 2021 (2021)
BioMed Research International

Hepatocellular carcinoma (HCC) is one of the most common and lethal malignancies worldwide. Although there have been extensive studies on the molecular mechanisms of its carcinogenesis, FDA-approved drugs for HCC are rare. Side effects, development t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311cc3cde309f72bde136807bccbc592
https://doaj.org/article/bc02d5a3630e49ba95b1bb9ad31c5497

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NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications

N-α-acetyltransferase D (NatD) mediates N-α-terminal acetylation (Nt-acetylation) of histone H4 known to be involved in cell growth. Here we report that NatD promotes the migratory and invasive capabilities of lung cancer cells in vitro and in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6795cfeb6d1d3652a5b7a05ea0d8222
http://link.springer.com/article/10.1038/s41467-017-00988-5

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ε-globin expression is regulated by SUV4-20h1

Autor: Yadong Wang, Loretta Cerruti, Min Nie, Ren-Xiang Tan, Zhuchen Li, Ming Liu, Yupeng Wu, Changjiang Zeng, Chi Ma, Stephen M. Jane, Junyi Ju, Gerhard Rank, Ying Wang, Gunnar Schotta, Feifei Huang, Alexander Nuber, Quan Zhao

Research efforts to establish therapeutic modalities for treating sickle cell disease (SCD) and β-thalassemia have been hindered by our incomplete understanding of the developmental regulation of human β-like globin gene expression. It has been dem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb03d8710cb3336397d2a7c0d1aa8cf
https://europepmc.org/articles/PMC5004379/

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gdt1, a New Signal Transduction Component for Negative Regulation of the Growth–Differentiation Transition inDictyostelium discoideum

Autor: Changjiang Zeng, Karsten Riemann, Angelika Konzok, Wolfgang Nellen, Christophe Anjard

Publikováno v: Molecular Biology of the Cell. 11:1631-1643

Discoidin I expression was used as a marker to screen for mutants affected in the growth–differentiation transition (GDT) ofDictyostelium. By REMI mutagenesis we have isolated mutant 2-9, an overexpressor of discoidin I. It displays normal morphoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776fe9662583c3c7521d0520cdf92259
https://doi.org/10.1091/mbc.11.5.1631

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Large-insert BAC/YAC libraries for selective re-isolation of genomic regions by homologous recombination in yeast

Autor: Pieter J. de Jong, Changjiang Zeng, George A. M. Cross, Natalay Kouprina, Vladimir Larionov, Baoli Zhu, Kazutoyo Osoegawa, Al Cairo, Maarten Hoek

Publikováno v: Genomics. 77(1-2)

We constructed representative large-insert bacterial artificial chromosome (BAC) libraries of two human pathogens (Trypanosoma brucei and Giardia lamblia) using a new hybrid vector, pTARBAC1, containing a yeast artificial chromosome (YAC) cassette (a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51686963ac44a8cd9926e6df74e025e4
https://pubmed.ncbi.nlm.nih.gov/11543629

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Interaction of gdt1 and protein kinase A (PKA) in the growth-differentiation-transition in Dictyostelium

Autor: Birgit Wetterauer, Changjiang Zeng, Christophe Anjard, Wolfgang Nellen, Gerd Primpke, Sandra Wille

Publikováno v: Differentiation; research in biological diversity. 67(1-2)

The gdt1 gene is a negative regulator of the growth-differentiation-transition (GDT) in Dictyostelium. gdt1- cells express the GDT marker discoidin earlier and at higher levels and prematurely enter the differentiation pathway. Protein kinase A is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcd8ee2a2ac343f812f2962857acf1a
https://pubmed.ncbi.nlm.nih.gov/11270120

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A bacterial artificial chromosome library for sequencing the complete human genome

Autor: Kazutoyo Osoegawa, Joseph J. Catanese, Aaron G. Mammoser, Chenyan Wu, Changjiang Zeng, Eirik Frengen, Pieter J. de Jong

Publikováno v: Genome research. 11(3)

A 30-fold redundant human bacterial artificial chromosome (BAC) library with a large average insert size (178 kb) has been constructed to provide the intermediate substrate for the international genome sequencing effort. The DNA was obtained from a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca72e66d53d35f0d3d29806ef05186b
https://pubmed.ncbi.nlm.nih.gov/11230172

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