Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Changjia, Zhong"'
Autor:
Fang Du, Douglas G. Walker, Changjia Zhong, Shijun Yan, Justin T. Douglas, Long Wu, Zhihua Zhang, Qing Yu, Lih-Fen Lue, Yongfu Wang, Shirley ShiDu Yan
Publikováno v:
Diabetes
Mitochondrial abnormalities are well known to cause cognitive decline. However, the underlying molecular basis of mitochondria-associated neuronal and synaptic dysfunction in the diabetic brain remains unclear. Here, using a mitochondrial single-chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba10a842c21274eb260bac34a8dd464d
https://doi.org/10.2337/db16-0556
https://doi.org/10.2337/db16-0556
Autor:
Heng Du, Du Fang, Molly Rabinowitz, Shiqiang Yan, John Xi Chen, Ottavio Arancio, Jhansi Rani Vangavaragu, Yongfu Wang, Zhihua Zhang, Shirley ShiDu Yan, Guy M. McKhann, Shijun Yan, Gang Hu, Elzbieta Glaser, Alexander A. Sosunov, Long Wu, Lan Guo, Qinru Sun, Changjia Zhong
Publikováno v:
Human Molecular Genetics. 24:5198-5210
Accumulation of amyloid-β (Aβ) in synaptic mitochondria is associated with mitochondrial and synaptic injury. The underlying mechanisms and strategies to eliminate Aβ and rescue mitochondrial and synaptic defects remain elusive. Presequence protea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30fa8a5a7ad00b3a93ea65b89382fa3
https://doi.org/10.1093/hmg/ddv241
https://doi.org/10.1093/hmg/ddv241
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 14:360-369
Notoginsenoside R1 (NTR1) is the main active ingredient of the well-known traditional Chinese herbal medicine Panax notoginseng, the root of Panax notoginseng (Burk.) F. H. Chen. Studies demonstrated that NTR1 may have some neuronal protective effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b58bc7319b373e11d794f83f1c1640e
https://doi.org/10.2174/1871527314666150225141521
https://doi.org/10.2174/1871527314666150225141521
Publikováno v:
Journal of Alzheimer's Disease. 43:451-463
Diabetes is considered to be a risk factor in Alzheimer’s disease (AD) pathogenesis. Although recent evidence indicates that diabetes exaggerates pathologic features of AD, the underlying mechanisms are not well understood. To determine whether mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c732e740d59531622ed29c5127d0fcfa
https://doi.org/10.3233/jad-140972
https://doi.org/10.3233/jad-140972
Autor:
Changjia Zhong, Long Wu, Shengbin Huang, Alexander A. Sosunov, Du Fang, Haiyang Yu, Xueqi Gan, Gang Hu, Shirley ShiDu Yan, Guy M. McKhann, Yongfu Wang
Publikováno v:
Diabetes
Diabetes has adverse effects on the brain, especially the hippocampus, which is particularly susceptible to synaptic injury and cognitive dysfunction. The underlying mechanisms and strategies to rescue such injury and dysfunction are not well underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c260027f8aca5f3984e82137f70f4d4b
https://doi.org/10.2337/db14-0758
https://doi.org/10.2337/db14-0758
Autor:
John Xi Chen, Xueqi Gan, Russell H. Swerdlow, Honglian Shi, Haiyang Yu, Long Wu, Shengbin Huang, Guangyue Li, Changjia Zhong, Shirley ShiDu Yan
Publikováno v:
Free Radical Biology and Medicine. 75:230-240
Mild cognitive impairment (MCI) occurs during the predementia stage of Alzheimer disease (AD) and is characterized by a decline in cognitive abilities that frequently represents a transition between normal cognition and AD dementia. Its pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bc8e0b558a9db7b08baa99743f55c0
https://doi.org/10.1016/j.freeradbiomed.2014.07.021
https://doi.org/10.1016/j.freeradbiomed.2014.07.021
Publikováno v:
CNSneurological disorders drug targets. 14(3)
Notoginsenoside R1 (NTR1) is the main active ingredient of the well-known traditional Chinese herbal medicine Panax notoginseng, the root of Panax notoginseng (Burk.) F. H. Chen. Studies demonstrated that NTR1 may have some neuronal protective effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e53b2cf20edfb1d9f3787bf506a0455
https://pubmed.ncbi.nlm.nih.gov/25714973
https://pubmed.ncbi.nlm.nih.gov/25714973
Autor:
Shijun Yan, Fang Du, Long Wu, Zhihua Zhang, Changjia Zhong, Qing Yu, Yongfu Wang, Lih-Fen Lue, Walker, Douglas G., Douglas, Justin T., ShiDu Yan, Shirley
Publikováno v:
Diabetes; Nov2016, Vol. 65 Issue 11, p3482-3494, 13p, 6 Graphs
Autor:
Du Fang, Yongfu Wang, Zhihua Zhang, Heng Du, Shiqiang Yan, Qinru Sun, Changjia Zhong, Long Wu, Vangavaragu, Jhansi Rani, Shijun Yan, Gang Hu, Lan Guo, Rabinowitz, Molly, Glaser, Elzbieta, Arancio, Ottavio, Sosunov, Alexander A., McKhann, Guy M., Xi Chen, John, ShiDu Yan, Shirley
Publikováno v:
Human Molecular Genetics; 9/15/2015, Vol. 24 Issue 18, p5198-5210, 13p
Autor:
Shengbin Huang, Yongfu Wang, Xueqi Gan, Du Fang, Changjia Zhong, Long Wu, Gang Hu, Sosunov, Alexander A., McKhann, Guy M., Haiyang Yu, ShiDu Yan, Shirley
Publikováno v:
Diabetes; May2015, Vol. 64 Issue 5, p1728-1742, 15p, 6 Color Photographs, 1 Graph