Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Changil Kim"'
Autor:
Marco Mandolesi, Hrishikesh Das, Liset de Vries, Yiqiu Yang, Changil Kim, Manojj Dhinakaran, Xaquin Castro Dopico, Julian Fischbach, Sungyong Kim, Mariia V. Guryleva, Monika Àdori, Mark Chernyshev, Aron Stålmarck, Leo Hanke, Gerald M. McInerney, Daniel J. Sheward, Martin Corcoran, B. Martin Hällberg, Ben Murrell, Gunilla B. Karlsson Hedestam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The continued evolution of SARS-CoV-2 underscores the need to understand qualitative aspects of the humoral immune response elicited by spike immunization. Here, we combine monoclonal antibody (mAb) isolation with deep B cell receptor (BCR)
Externí odkaz:
https://doaj.org/article/dd5bb1c8958649a5ad5a309a8a4fa7ee
Autor:
Klara Lenart, Rodrigo Arcoverde Cerveira, Fredrika Hellgren, Sebastian Ols, Daniel J. Sheward, Changil Kim, Alberto Cagigi, Matthew Gagne, Brandon Davis, Daritza Germosen, Vicky Roy, Galit Alter, Hélène Letscher, Jérôme Van Wassenhove, Wesley Gros, Anne-Sophie Gallouët, Roger Le Grand, Harry Kleanthous, Mimi Guebre-Xabier, Ben Murrell, Nita Patel, Gregory Glenn, Gale Smith, Karin Loré
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract The immune responses to Novavax’s licensed NVX-CoV2373 nanoparticle Spike protein vaccine against SARS-CoV-2 remain incompletely understood. Here, we show in rhesus macaques that immunization with Matrix-MTM adjuvanted vaccines predominant
Externí odkaz:
https://doaj.org/article/c088a289c59c484090d22680d31eac78
Autor:
Khristine Joy C. Antigua, Yun Hee Baek, Won-Suk Choi, Ju Hwan Jeong, Eun-Ha Kim, Sol Oh, Sun-Woo Yoon, Changil Kim, Eung-Gook Kim, So-Young Choi, Seung Kon Hong, Young Ki Choi, Min Suk Song
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 990-1004 (2022)
Novel highly pathogenic avian influenza (HPAI) H5Nx viruses are predominantly circulating worldwide, with an increasing potential threat of an outbreak in humans. It remains largely unknown how the stably maintained HPAI H5N1 suddenly altered its neu
Externí odkaz:
https://doaj.org/article/9e0f757b4751478fa21315f479f75de9
Autor:
Leo Hanke, Hrishikesh Das, Daniel J. Sheward, Laura Perez Vidakovics, Egon Urgard, Ainhoa Moliner-Morro, Changil Kim, Vivien Karl, Alec Pankow, Natalie L. Smith, Bartlomiej Porebski, Oscar Fernandez-Capetillo, Erdinc Sezgin, Gabriel K. Pedersen, Jonathan M. Coquet, B. Martin Hällberg, Ben Murrell, Gerald M. McInerney
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here, the authors isolate and characterize a bispecific monomeric nanobody that induces dimerization of SARS-CoV-2 spike trimers, neutralizes variants of concerns as well as SARS-CoV, and inhibits SARS-CoV-2 infection in mice.
Externí odkaz:
https://doaj.org/article/f14234a7e3914ec1bbba1c457db3bda6
Autor:
Daniel J. Sheward, Marco Mandolesi, Egon Urgard, Changil Kim, Leo Hanke, Laura Perez Vidakovics, Alec Pankow, Natalie L. Smith, Xaquin Castro Dopico, Gerald M. McInerney, Jonathan M. Coquet, Gunilla B. Karlsson Hedestam, Ben Murrell
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 11, Pp 100450- (2021)
Summary: Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) with resistance to neutralizing antibodies are threatening to undermine vaccine efficacy. Vaccination and infection have led to widespread humoral immuni
Externí odkaz:
https://doaj.org/article/f6fbb94e1aa445b28a40632a0756d791
Publikováno v:
IEEE Access, Vol 7, Pp 155158-155170 (2019)
For automated driving technology to move beyond the proof stage and into actual automated driving, it is important to verify the safety of the automated driving system. In this paper, a method to ensure lateral control safety for the lane detection f
Externí odkaz:
https://doaj.org/article/3c1c995868424fc98c9083111ae33d10
Autor:
Marco Mandolesi, Daniel J. Sheward, Leo Hanke, Junjie Ma, Pradeepa Pushparaj, Laura Perez Vidakovics, Changil Kim, Monika Àdori, Klara Lenart, Karin Loré, Xaquin Castro Dopico, Jonathan M. Coquet, Gerald M. McInerney, Gunilla B. Karlsson Hedestam, Ben Murrell
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 4, Pp 100252- (2021)
Summary: The outbreak and spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) is a current global health emergency, and effective prophylactic vaccines are needed urgently. The spike glycoprotein of SARS-CoV-2 mediates entry into h
Externí odkaz:
https://doaj.org/article/7dc9142914f7465a886ef3bfa6172c42
Autor:
Xu Jing, Jieyu Wu, Caijuan Dong, Juan Gao, Takahiro Seki, Changil Kim, Egon Urgard, Kayoko Hosaka, Yunlong Yang, Siwen Long, Ping Huang, Junnian Zheng, Laszlo Szekely, Yuanting Zhang, Wei Tao, Jonathan Coquet, Minghua Ge, Yuguo Chen, Mikael Adner, Yihai Cao
Publikováno v:
Nature Metabolism. 4:1674-1683
Patients with COVID-19 frequently manifest adipose atrophy, weight loss and cachexia, which significantly contribute to poor quality of life and mortality1,2. Browning of white adipose tissue and activation of brown adipose tissue are effective proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8890efc85963d9767b617d9d65d4d43d
https://doi.org/10.1038/s42255-022-00697-4
https://doi.org/10.1038/s42255-022-00697-4
Autor:
Daniel J Sheward, Changil Kim, Roy A Ehling, Alec Pankow, Xaquin Castro Dopico, Robert Dyrdak, Darren P Martin, Sai T Reddy, Joakim Dillner, Gunilla B Karlsson Hedestam, Jan Albert, Ben Murrell
Publikováno v:
The Lancet. Infectious diseases
The SARS-CoV-2 omicron (B.1.1.529) variant, which was first identified in November, 2021, spread rapidly in many countries, with a spike protein highly diverged from previously known variants, and raised concerns that this variant might evade neutral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c7e8735ad1b0c5fad09b3492ba81a0
https://doi.org/10.1016/s1473-3099(22)00129-3
https://doi.org/10.1016/s1473-3099(22)00129-3
Autor:
Su-Jae Lee, Kee-Ho Lee, Haekwon Kim, Young-Hyun Choi, Changil Kim, Sang-Gu Hwang, In-Chul Park, Soon-Young Choi, Min-Jung Kim
Exposure of cells to ionizing radiation induces activation of multiple signaling pathways that play critical roles in determining cell fate. However, the molecular basis for cell death or survival signaling in response to radiation is unclear at pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31747c826fb1fdc05d908824a772a3f0
https://doi.org/10.1158/1541-7786.c.6541786.v1
https://doi.org/10.1158/1541-7786.c.6541786.v1
