Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Changhun Park"'
1
Akademický článek
Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy
Autor: Jongsung Hahn, Seungwon Yang, Kyoung Lok Min, Dasohm Kim, Byung Hak Jin, Changhun Park, Min Soo Park, Jin Wi, Min Jung Chang
Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-10 (2019)
Abstract Background Sufentanil is commonly used for analgesia and sedation during extracorporeal membrane oxygenation (ECMO). Both ECMO and the pathophysiological changes derived from critical illness have significant effects on the pharmacokinetics
Externí odkaz: https://doaj.org/article/93969ca6b1654d96928e34b1920bc4d0
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2
Akademický článek
Effects of Pioglitazone on Nonalcoholic Fatty Liver Disease in the Absence of Constitutive Androstane Receptor Expression
Autor: Hwa Young Ahn, Hwan Hee Kim, Ji-Yeon Hwang, Changhun Park, Bo Youn Cho, Young Joo Park
Publikováno v: PPAR Research, Vol 2018 (2018)
Nonalcoholic fatty liver disease or steatohepatitis (NAFLD/NASH) is a fatty liver disease that is closely related to obesity, diabetes, and dyslipidemia. Pioglitazone, which was developed as an antidiabetic drug, is known to improve NALFD. Pioglitazo
Externí odkaz: https://doaj.org/article/82e76e0f924745b3ae56736ad099f561
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4
Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy
Autor: Dasohm Kim, Min Jung Chang, Min Soo Park, Byung Hak Jin, Jin Wi, Seungwon Yang, Jongsung Hahn, Changhun Park, Kyoung Lok Min
Publikováno v: Critical Care, Vol 23, Iss 1, Pp 1-10 (2019)
Critical Care
Background Sufentanil is commonly used for analgesia and sedation during extracorporeal membrane oxygenation (ECMO). Both ECMO and the pathophysiological changes derived from critical illness have significant effects on the pharmacokinetics (PK) of d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103ee54edc03584c4b82a281236c2030
https://doi.org/10.1186/s13054-019-2508-4
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6
The regulation of 2,3-butanediol synthesis in Klebsiella pneumoniae as revealed by gene over-expressions and metabolic flux analysis
Autor: Youngsoon Um, Min Kyu Oh, Soojin Lee, Jinwon Lee, Jungwook Kim, Borim Kim, Mingshou Lu, Changhun Park
Publikováno v: Bioprocess and Biosystems Engineering. 37:343-353
A variety of microorganism species are able naturally to produce 2,3-butanediol (2,3-BDO), although only a few of them are suitable for consideration as having potential for mass production purposes. Klebsiella pneumoniae (K. pneumoniae) is one such
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857e17f81bae980abf7e5877497156be
https://doi.org/10.1007/s00449-013-0999-y
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7
Pharmacokinetics of a nanocrystal-containing megestrol acetate formulation: a single-dose, randomized, open-label, 2-part, 2-period crossover study in healthy Korean subjects
Autor: Jinju Guk, Hankil Son, Kyungsoo Park, Changhun Park, Dongwoo Chae
Publikováno v: International journal of clinical pharmacology and therapeutics. 54(9)
UNLABELLED OBJECTIVE The conventional suspension of megestrol acetate contains micronized megestrol acetate, which was recently discovered to have a disadvantage of decreasing bioavailability when taken in a fasting state. Since megestrol acetate is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb449f5a9a6e61c8af92f1493f669ee
https://pubmed.ncbi.nlm.nih.gov/27191767
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8
Identification of Factors Regulating Escherichia coli 2,3-Butanediol Production by Continuous Culture and Metabolic Flux Analysis
Autor: Kyungmoon Park, Min Kyu Oh, Borim Kim, Mingshou Lu, Soojin Lee, Sang Yup Lee, Changhun Park, Jinwon Lee
Publikováno v: Journal of Microbiology and Biotechnology. 22:659-667
2,3-Butanediol (2,3-BDO) is an organic compound with a wide range of industrial applications. Although Escherichia coli is often used for the production of organic compounds, the wild-type E. coli does not contain two essential genes in the 2,3-BDO b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8fbca33882941ae943ea9f5e2c91327
https://doi.org/10.4014/jmb.1112.12018
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9
Parameter estimation and dynamic control analysis of central carbon metabolism in Escherichia coli
Autor: Wangyun Won, Changhun Park, Sang Yup Lee, Kwang Soon Lee, Jinwon Lee
Publikováno v: Biotechnology and Bioprocess Engineering. 16:216-228
The central carbon metabolic pathway is the most important among metabolic pathways in all microorganisms since it produces energy and precursors for biosynthesis. In this study, a dynamic model for central carbon metabolism in Escherichia coli (E. c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b01d46bfefa599fbf256087a05bdb57
https://doi.org/10.1007/s12257-010-0238-1
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10
Determination of the Intracellular Concentrations of Metabolites in Escherichia coli Collected during the Exponential and Stationary Growth Phases using Liquid Chromatography-Mass Spectrometry
Autor: Changhun Park, Jinwon Lee, Youn Jin Lee, Han Bin Oh, Sang Yup Lee
Publikováno v: Bulletin of the Korean Chemical Society. 32:524-530
In the present study, we demonstrate that SRM LC-MS/MS method developed by Luo et al. (ref. 10) can be successfully applied to the quantitative analysis of intracellular metabolites in E. coli that are collected at the exponential and statio- nary gr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::465445250af3275fda71c1fa17d764fb
https://doi.org/10.5012/bkcs.2011.32.2.524
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