Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Changhong Qiao"'
Autor:
Dingyu Liu, Baoling Liu, Zhenwen He, Changhong Qiao, Qin Luo, Xiangyu Chen, Xiaohu Wang, Hua Xiang, Jing Chen, Pian Zhang, Yuan Huang, Gang Wang, Chen Tan, Rujian Cai
Publikováno v:
Animals, Vol 14, Iss 13, p 1861 (2024)
The Hepatitis E virus (HEV) causes acute and chronic Hepatitis E and is a global public health concern. HEV genotypes 3 (HEV-3) and 4 (HEV-4) are common to humans and animals, and domestic pigs and wild boars have been identified as the main reservoi
Externí odkaz:
https://doaj.org/article/52e04df3d5f347c1b85cb95c76134e43
Autor:
Marcello Ziosi, Ivano Di Meo, Giulio Kleiner, Xing‐Huang Gao, Emanuele Barca, Maria J Sanchez‐Quintero, Saba Tadesse, Hongfeng Jiang, Changhong Qiao, Richard J Rodenburg, Emmanuel Scalais, Markus Schuelke, Belinda Willard, Maria Hatzoglou, Valeria Tiranti, Catarina M Quinzii
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 1, Pp 96-111 (2016)
Abstract Coenzyme Q (CoQ) is an electron acceptor for sulfide‐quinone reductase (SQR), the first enzyme of the hydrogen sulfide oxidation pathway. Here, we show that lack of CoQ in human skin fibroblasts causes impairment of hydrogen sulfide oxidat
Externí odkaz:
https://doaj.org/article/c93d874d27cf40a7a84b8c58b34251f8
Data from Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Purpose:Both gain-of-function enhancer of zeste homolog 2 (EZH2) mutations and inactivating histone acetyltransferases mutations, such as CREBBP and EP300, have been implicated in the pathogenesis of germinal center (GC)–derived lymphomas. We hypot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c25494f751d349c18a9a0f314e919e
https://doi.org/10.1158/1078-0432.c.6527655
https://doi.org/10.1158/1078-0432.c.6527655
Autor:
Jennifer E. Amengual, Olivier Elemento, Neil L. Kelleher, Serge Cremers, Renu Nandakumar, Changhong Qiao, Emily I. Chen, Swasti Mehta, Jeannie M. Camarillo, Nebiyu Abshiru, Prabhjot S. Mundi, Akanksha Verma, Yulissa Gonzalez, Yuxuan Liu, Sathyen A. Prabhu, Jennifer K. Lue
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3a7acc7afb6706436cb46f252d3e0a
https://doi.org/10.1158/1078-0432.22470681
https://doi.org/10.1158/1078-0432.22470681
Autor:
Giulio Kleiner, Agustín Hidalgo-Gutiérrez, Luis C. López, Emanuele Barca, Valentina Emmanuele, Saba Tadesse, Yimeng Xu, Marcello Ziosi, Estela Area-Gomez, Changhong Qiao, Catarina M. Quinzii
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3708-3722
Nephrotic syndrome (NS), a frequent chronic kidney disease in children and young adults, is the most common phenotype associated with primary coenzyme Q(10) (CoQ(10)) deficiency and is very responsive to CoQ(10) supplementation, although the pathomec
Autor:
Andrea Califano, Jennifer K. Lue, Eugene Douglass, Beatrice Casadei, Francesca Montanari, Enrica Marchi, Nandakumar Renu, Changchun Deng, Luigi Scotto, Susan E. Bates, Changhong Qiao, Maryam Safari, Owen A. O'Connor, Cristina Kinahan, Lorenzo Falchi
Publikováno v:
Mol Cancer Ther
The peripheral T-cell lymphomas (PTCL) could be considered the prototypical epigenetic disease. As a disease, they are uniquely sensitive to histone deacetylase (HDAC) and DNA methyltransferase (DNMT) inhibitors, both alone and in combination, are ch
Autor:
Jennifer E Amengual, Emily I. Chen, Neil L. Kelleher, Olivier Elemento, Prabhjot Mundi, Jennifer K. Lue, Nebiyu Abshiru, Jeannie M. Camarillo, Yulissa Gonzalez, Changhong Qiao, Serge Cremers, Sathyen A. Prabhu, Swasti Mehta, Renu Nandakumar, Akanksha Verma, Yuxuan Liu
Publikováno v:
Clin Cancer Res
Purpose: Both gain-of-function enhancer of zeste homolog 2 (EZH2) mutations and inactivating histone acetyltransferases mutations, such as CREBBP and EP300, have been implicated in the pathogenesis of germinal center (GC)–derived lymphomas. We hypo
Autor:
Adolfo Mazzeo, Yuxuan Liu, Owen A. O'Connor, Jennifer E Amengual, Shixian Deng, Elisa Calcagno, Cremers Serge, Elisa Zuccarello, Nebiyu Abshiru, Yulissa Gonzalez, Jeannie M. Camarillo, Donald W. Landry, Jole Fiorito, Changhong Qiao, Neil L. Kelleher, Ottavio Arancio, Renu Nandakumar
Publikováno v:
Blood. 132:37-37
Monoalleleic inactivating mutations in histone acetyltransferase (HAT) enzymes promote lymphomagenesis in germinal center derived B-cell lymphomas, follicular lymphoma (FL) and diffuse large B cell lymphoma (DLBCL), occurring in about 40% of patients
Autor:
Yuxuan Liu, Serge Cremers, Changhong Qiao, Renu Nandakumar, Sathyen A. Prabhu, Jennifer E Amengual, Akanksha Verma, Neil L. Kelleher, Jennifer K. Lue, Nebiyu Abshiru, Yulissa Gonzalez, Emily I. Chen, Olivier Elemento
Publikováno v:
Journal of Clinical Oncology. 36:7546-7546
7546Background: EZH2 is the catalytic subunit of PRC2, and induces methylation of H3K27. Activating mutations and overexpression of EZH2 are found in NHL. Inactivating mutations in histone acetyltr...
Autor:
Celeste Rojas, Emily Lichtenstien, Karen Kahn, Jennifer E Amengual, Ahmed Sawas, Serge Cremers, Renu Nandakumar, Yuxuan Liu, Changhong Qiao, Owen A. O'Connor, Jennifer K. Lue, Changchun Deng, Renee Lichtenstein
Publikováno v:
Blood. 128:1824-1824
Peripheral T-cell lymphoma (PTCL) is a heterogeneous group of lymphomas in which only ~25% of patients experience long-term survival with CHOP chemotherapy. Recently several drugs have been approved for this entity including pralatrexate (P), romidep