Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Changhee Ha"'
Autor:
Young-gon Kim, Hyunju Kang, Beomki Lee, Hyeok-Jae Jang, Jong-ho Park, Changhee Ha, Hogun Park, Jong-Won Kim
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Despite its importance for regulating gene expression, nonsense-mediated mRNA decay (NMD) remains poorly understood. Here, we extend the findings of a previous landmark study that proposed several factors associated with NMD efficiency using
Externí odkaz:
https://doaj.org/article/97c60f358b134d8a8056f79cde7e8f3b
Autor:
Young-gon Kim, Boram Lee, Changhee Ha, Cheonghwa Lee, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Myung-Ju Ahn, Yoon-La Choi, Sehhoon Park, Jong-Won Kim
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionNumerous studies have suggested high concordance between tissue and circulating tumor DNA (ctDNA) comprehensive genomic profiling (CGP) tests but only few of them focused on fusions. In addition, atypical breakpoints occasionally detected
Externí odkaz:
https://doaj.org/article/dbc81487172d4e9cb14580b7c5c23ec4
Autor:
Woong Ki Park, Soo Yeon Chung, You Jin Jung, Changhee Ha, Jong-Won Kim, Seok Jin Nam, Seok Won Kim, Jonghan Yu, Byung Joo Chae, Jeong Eon Lee, Sung-Won Kim, Jai Min Ryu, Korean Hereditary Breast Cancer Study Group
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-7 (2024)
Abstract Triple-negative breast cancer (TNBC) patients are more likely to have BRCA1/2 mutations, with a prevalence rate of about 10–20%. Although several studies have analyzed the oncologic outcomes between BRCA1/2 carriers and non-carriers, the i
Externí odkaz:
https://doaj.org/article/41e125ef00064d8398ebcb27fe14b877
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: RNA sequence analysis can be effectively used to identify aberrant splicing, and tumor suppressor genes are adequate targets considering their loss-of-function mechanisms. Sanger sequencing is the simplest method for RNA sequence analys
Externí odkaz:
https://doaj.org/article/3929c3d11572458d93308b262879befa
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Titin truncating variants (TTNtvs) are the most common genetic cause of dilated cardiomyopathy (DCM). Among four regions of titin, A-band enrichment of DCM-causing TTNtvs is widely accepted but the underlying mechanism is still unknown. Meanwhile, fe
Externí odkaz:
https://doaj.org/article/0f43fd56d58e4f5c9465c23cacec27aa
Autor:
Changhee Ha, Hyun-Seung Lee, Eun Yeon Joo, Young-Min Shon, Seung Bong Hong, Dae-Won Seo, Soo-Youn Lee
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 826 (2021)
Levetiracetam is a new antiepileptic drug (AED) used for treating and preventing partial or generalized seizures. The usefulness of levetiracetam therapeutic drug monitoring (TDM) is related to inter- or intra-individual pharmacokinetic variability,
Externí odkaz:
https://doaj.org/article/0ea795c1fd4349d09ec2b7c4b77554d4
Publikováno v:
Laboratory Medicine Online. 12:116-121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9a80ef44f6606b6cf14d1b11da2ede9
https://doi.org/10.47429/lmo.2022.12.2.116
https://doi.org/10.47429/lmo.2022.12.2.116
Autor:
Changhee Ha, Sang Jin Kim, Jong Man Kim, Jae-Won Joh, Kee-Taek Jang, Gyu-Seong Choi, Eun-Suk Kang
Publikováno v:
Annals of Transplantation. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::268f35f45548c7900cafa7a7b625eca1
https://doi.org/10.12659/aot.938287
https://doi.org/10.12659/aot.938287
Autor:
Young-gon Kim, Hyemi Kwon, Jong-ho Park, Soo Hyun Nam, Changhee Ha, Sunghwan Shin, Won Young Heo, Hye Jin Kim, Ki Wha Chung, Ja-Hyun Jang, Jong-Won Kim, Byung-Ok Choi
Publikováno v:
Brain Communications. 5
Whole-genome sequencing is the most comprehensive form of next-generation sequencing method. We aimed to assess the additional diagnostic yield of whole-genome sequencing in patients with clinically diagnosed Charcot–Marie–Tooth disease when comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75dd17b8b86d237c03fcaa4062814ba0
https://doi.org/10.1093/braincomms/fcad139
https://doi.org/10.1093/braincomms/fcad139
Publikováno v:
Laboratory Medicine Online. 11:55-59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00963c96e36de8e9e9bb7125640de582
https://doi.org/10.47429/lmo.2021.11.1.55
https://doi.org/10.47429/lmo.2021.11.1.55