Zobrazeno 1 - 10
of 419
pro vyhledávání: '"Changgeng, Ruan"'
Autor:
Xiuyan Zhang, Yu Wang, Jinchang Lu, Lun Xiao, Hui Chen, Quanxue Li, Yuan-Yuan Li, Peng Xu, Changgeng Ruan, Haixia Zhou, Yun Zhao
Publikováno v:
Cellular & Molecular Biology Letters, Vol 28, Iss 1, Pp 1-19 (2023)
Abstract Background Zinc finger protein X-linked (ZFX) has been shown to promote the growth of tumor cells, including leukemic cells. However, the role of ZFX in the growth and drug response of chronic myeloid leukemia (CML) stem/progenitor cells rem
Externí odkaz:
https://doaj.org/article/e436e224d1b14725b4956af4f5a8b834
Autor:
Ningbo Pang, Yingwei Li, Kangxi Zhou, Chunliang Liu, Rong Yan, Chenglin Sun, Weiling Xiao, Changgeng Ruan, Zhimin Zhai, Kesheng Dai
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTObjectives Cyclic thrombocytopenia (CTP) is a rare blood disorder characterized by periodic fluctuations in platelet counts. CTP usually appears in pre-menopausal women, and these fluctuations of platelets are in phase with the menstrual cycl
Externí odkaz:
https://doaj.org/article/ffe06407db2c413294f4abf0fbf57fe2
Autor:
Hong Wang, Qingyuan Wang, Jiaqian Qi, Xueqian Li, Tiantian Chu, Huiying Qiu, Chengcheng Fu, Xiaowen Tang, Changgeng Ruan, Depei Wu, Yue Han
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PurposeAppropriate pre-transplant strategies in patients with myelodysplastic syndromes (MDS) remain challenging. We sought to assess the effect of different pre-transplant therapies and transplantation interval times on patient prognosis.MethodsWe r
Externí odkaz:
https://doaj.org/article/27a88ad9909d4d84bfe54bec16e2d60a
Autor:
Li Huo, Jundan Xie, Qian Wang, Hongjie Shen, Zixuan Ding, Lijun Wen, Zhao Zeng, Yi Xu, Changgeng Ruan, Suning Chen, Mengxing Xue
Publikováno v:
Clinical Case Reports, Vol 11, Iss 1, Pp n/a-n/a (2023)
Abstract Myeloproliferative neoplasms (MPNs) with concurrent BCR‐ABL1 fusion gene and CALR mutation are especially rare. We report a patient with coexisting BCR‐ABL1 fusion gene, CALR, and TET2 mutations who was treated with the combination of th
Externí odkaz:
https://doaj.org/article/d6db3714854f4969814958734313db10
Autor:
Rong Yan, Xinxin Ge, Ningbo Pang, Honglei Ye, Liuxia Yuan, Bin Cheng, Kangxi Zhou, Mengnan Yang, Yueyue Sun, Suqin Zhang, Zhongren Ding, Jincai Luo, Changgeng Ruan, Kesheng Dai
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Abstract Platelets are generated from the cytoplasm of megakaryocytes (MKs) via actin cytoskeleton reorganization. Zyxin is a focal adhesion protein and wildly expressed in eukaryotes to regulate actin remodeling. Zyxin is upregulated during megakary
Externí odkaz:
https://doaj.org/article/65bcc0b3e8974c0ab597321e2ecbc3ee
Autor:
Tiantian Chu, Hong Wang, Xin Lv, Jiaqian Qi, Yaqiong Tang, Yi Fan, Huiying Qiu, Xiaowen Tang, Chengcheng Fu, Changgeng Ruan, Yue Han, De-Pei Wu
Publikováno v:
Platelets, Vol 32, Iss 5, Pp 677-683 (2021)
Early hemorrhagic death remains a major cause of treatment failure in acute promyelocytic leukemia (APL). This study investigated the role of fibrinogen concentrations in early hemorrhage and overall survival (OS) of APL patients. Laboratory and clin
Externí odkaz:
https://doaj.org/article/663b5d43fc5a4582b10dc4d09a2d21b9
Autor:
Hong Wang, Jiaqian Qi, Xueqian Li, Tiantian Chu, Huiying Qiu, Chengcheng Fu, Xiaowen Tang, Changgeng Ruan, Depei Wu, Yue Han
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Prolonged isolated thrombocytopenia (PT) is a common complication affecting the outcome of stem cell transplantation. In this study, we undertook a real-world study of 303 myelodysplastic syndrome (MDS) patients who received allogeneic hematopoietic
Externí odkaz:
https://doaj.org/article/af133bc60710442498e243aae87ecd5f
Autor:
Ziyan Zhang, Xiaojin Wu, Meng Zhou, Jiaqian Qi, Rui Zhang, Xueqian Li, Chang Wang, Changgeng Ruan, Yue Han
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
ITP is a common autoimmune bleeding disorder with elusive pathogenesis. Our study was implemented to profile the plasma metabolic alterations of patients diagnosed with ITP, aiming at exploring the potential novel biomarkers and partial mechanism of
Externí odkaz:
https://doaj.org/article/8f237c69901449908c68cac76e9b9a5b
Autor:
Xinfeng Wang, Xiaoyu Xu, Wenzhi Cai, Haiyan Bao, Hongming Huang, Yifei Liu, Xi Yang, Changgeng Ruan, Depei Wu, Hongjie Shen, Suning Chen
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-4 (2020)
Abstract Primary testicular lymphoma (PTL), often appearing as focal masses in the scrotum and epididymides, is the most frequent testicular tumor in aged men. Although MYD88 and CD79B mutations were the most common genetic alterations observed, the
Externí odkaz:
https://doaj.org/article/b7c31c01fbc148c48dfade699843d399
Autor:
Tongtong Zhang, Xiebing Bao, Huiying Qiu, Xiaowen Tang, Yue Han, Chengcheng Fu, Aining Sun, Changgeng Ruan, Depei Wu, Suning Chen, Yang Xu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Using targeted exome sequencing, we studied correlations between mutations at diagnosis and transplant outcomes in 332 subjects with acute myeloid leukemia (AML) receiving allotransplantation. A total of 299 patients (299/332, 90.1%) had at least one
Externí odkaz:
https://doaj.org/article/f6e128680f3c4281b8086a2455e78ce7