Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Changcheng, Zhang"'
Autor:
George L Hamilton, Nabanita Saikia, Sujit Basak, Franceine S Welcome, Fang Wu, Jakub Kubiak, Changcheng Zhang, Yan Hao, Claus AM Seidel, Feng Ding, Hugo Sanabria, Mark E Bowen
Publikováno v:
eLife, Vol 11 (2022)
The scaffold protein PSD-95 links postsynaptic receptors to sites of presynaptic neurotransmitter release. Flexible linkers between folded domains in PSD-95 enable a dynamic supertertiary structure. Interdomain interactions within the PSG supramodule
Externí odkaz:
https://doaj.org/article/253718a2b64044b084b1faac60a77f9a
Autor:
Yan Gao, Ding Yuan, Liyue Gai, Xuelian Wu, Yue Shi, Yumin He, Chaoqi Liu, Changcheng Zhang, Gang Zhou, Chengfu Yuan
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 3, Pp 408-419 (2021)
Background: The decreased renal function is known to be associated with biological aging, of which the main pathological features are chronic inflammation and renal interstitial fibrosis. In previous studies, we reported that total saponins from Pana
Externí odkaz:
https://doaj.org/article/b554846a7f61441e8fb9fbf01a0a18b5
Autor:
Jie Zheng, Shanshan Hu, Jinxin Wang, Xulan Zhang, Ding Yuan, Changcheng Zhang, Chaoqi Liu, Ting Wang, Zhiyong Zhou
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 183-191 (2021)
Context Icariin (ICA) is the main active ingredient of Epimedium brevicornu Maxim (Berberidaceae), which is used in the immune, reproductive, neuroendocrine systems, and anti-aging. Objective To evaluate the effect of ICA on natural aging rat. Materi
Externí odkaz:
https://doaj.org/article/9e54264f7ccc4b0790014292ef6c09ea
Autor:
Yanli Li, Jie Liu, Pawin Pongkorpsakol, Zhengguo Xiong, Li Li, Xuemei Jiang, Haixia Zhao, Ding Yuan, Changcheng Zhang, Yuhui Guo, Yaoyan Dun
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Inflammatory cytokines including TNF-α and IL-1β impair intestinal barrier function in aging by disrupting intestinal tight junction integrity. Icariin (ICA) has a variety of pharmacological effects. Indeed, ICA produces anti-inflammatory, anti-oxi
Externí odkaz:
https://doaj.org/article/facdbadfa5af4f1584c12c5e8d2c51e9
Autor:
Yue Shi, Zhengtai Liu, Liyue Gai, Yan Gao, Yumin He, Chaoqi Liu, Changcheng Zhang, Gang Zhou, Ding Yuan, Chengfu Yuan
Publikováno v:
Journal of Functional Foods, Vol 78, Iss , Pp 104369- (2021)
We aimed to investigate the effects of total saponins from Panax japonicus (TSPJ) on adipocyte inflammation and insulin resistance induced by a high-fat diet (HFD). Moreover, its underlying mechanism was further explored. In vivo, we found that TSPJ
Externí odkaz:
https://doaj.org/article/f6c078135d7a4ed785debcbb5d25f881
Autor:
Haixia Zhao, Xu You, Qian Chen, Siqi Yang, Qiongyan Ma, Yumin He, Chaoqi Liu, Yaoyan Dun, Jie Wu, Changcheng Zhang, Ding Yuan
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Sertoli cells play crucial roles in spermatogenesis and are impaired by aging. Icariin, a flavonoid from Epimedium, has been reported to exhibit anti-aging effects and improve testicular dysfunction in the clinical setting. However, whether icariin i
Externí odkaz:
https://doaj.org/article/fcf5e4b8e6524432a7ef468a6b77b8db
Publikováno v:
Complexity, Vol 2020 (2020)
Innovation subsidy is of great significance to promoting enterprise innovation development. However, in recent years, the frequent occurrence of R&D subsidy deception in China has greatly reduced effectiveness of innovation. From the perspective of t
Externí odkaz:
https://doaj.org/article/c79482eed4bb4b88b4d9fcf431309335
Autor:
Yaoyan Dun, Min Liu, Jing Chen, Danli Peng, Haixia Zhao, Zhiyong Zhou, Ting Wang, Chaoqi Liu, Yuhui Guo, Changcheng Zhang, Ding Yuan
Publikováno v:
Journal of Ginseng Research, Vol 42, Iss 1, Pp 50-56 (2018)
Background: Saponins from Panax japonicus (SPJ) are the most abundant and main active components of P. japonicus, which replaces ginseng roots in treatment for many kinds of diseases in the minority ethnic group in China. Our previous studies have de
Externí odkaz:
https://doaj.org/article/97da2fbe1978421ca8659dfe2649c668
Autor:
Dan Huang, Changcheng Zhang, Ming Xiao, Xie Li, Weicai Chen, Yu Jiang, Yamin Yuan, Yaping Zhang, Yejun Zou, Lei Deng, Yang Wang, Yuying Sun, Wenping Dong, Zhuo Zhang, Li Xie, Zhuo Yu, Chiqi Chen, Ligen Liu, Jing Wang, Yi Yang, Jie Yang, Yuzheng Zhao, Junke Zheng
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Rewiring of redox metabolism has a profound impact on tumor development, but how the cellular heterogeneity of redox balance affects leukemogenesis remains unknown. To precisely characterize the dynamic change in redox metabolism in vivo, we develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ee64f5b725d5d0f577df51e833ffd0
https://doi.org/10.1073/pnas.2210796120
https://doi.org/10.1073/pnas.2210796120
Autor:
Yaoyan Dun, Yanli Li, Yuhui Guo, Liu Aoqi, Chengquan Ma, Zhengguo Xiong, Ding Yuan, Changcheng Zhang, Jihong Zhang
Publikováno v:
Current Medicinal Chemistry. 30
Background: Lipopolysaccharide (LPS) is an endotoxin that causes inflammation, and the content of LPS increases gradually during the process of aging. Whether the response of the colon to LPS stimulation will increase with age is yet unknown. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d34ec95152e467ebcd4c9289a731f013
https://doi.org/10.2174/0929867330666230113112803
https://doi.org/10.2174/0929867330666230113112803