Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Changbin Shi"'
Publikováno v:
Guoji laonian yixue zazhi, Vol 45, Iss 4, Pp 444-447 (2024)
Objective To investigate the effect of stereotactic minimally invasive surgery on immune level and activities of daily living in elderly patients with glioma. Methods Ninety elderly patients with glioma admitted to the First Affiliated Hospital of Ha
Externí odkaz:
https://doaj.org/article/810261c6e62742769cd240d023136e01
Autor:
Guofu Li, Ziyu Xiong, Ying Li, Cong Yan, Yingying Cheng, Yuwen Wang, Jingwei Li, Zifeng Dai, Dongdong Zhang, Wenzhong Du, Chunyang Men, Changbin Shi
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Objective Glioma, a malignant primary brain tumor, is notorious for its high incidence rate. However, the clinical application of temozolomide (TMZ) as a treatment option for glioma is often limited due to resistance, which has been linked t
Externí odkaz:
https://doaj.org/article/56facc1dd2104f77bdb51978261e6b47
Autor:
Ying Li, Romuald Girard, Abhinav Srinath, Diana Vera Cruz, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel Romanos, Je Yeong Sone, Thomas Moore, Dorothy DeBiasse, Agnieszka Stadnik, Justine J. Lee, Robert Shenkar, Janne Koskimäki, Miguel A. Lopez-Ramirez, Douglas A. Marchuk, Mark H. Ginsberg, Mark L. Kahn, Changbin Shi, Issam A. Awad
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type
Externí odkaz:
https://doaj.org/article/05cc7d1857bb4df3a29deb810717fcd3
Autor:
Ying Li, Abhinav Srinath, Roberto J. Alcazar-Felix, Stephanie Hage, Akash Bindal, Rhonda Lightle, Robert Shenkar, Changbin Shi, Romuald Girard, Issam A. Awad
Publikováno v:
Brain Sciences, Vol 13, Iss 9, p 1336 (2023)
Cerebral cavernous malformation (CCM) is a common cerebrovascular malformation causing intracranial hemorrhage, seizures, and focal neurologic deficits. A unique CCM lesional inflammatory microenvironment has been shown to influence the clinical cour
Externí odkaz:
https://doaj.org/article/1e7394b03d734e489256bf278f7dabc7
Autor:
Zifeng Dai, Jingwei Li, Ying Li, Rui Wang, Huili Yan, Ziyu Xiong, Shiting Wu, Xi Yang, Dongbo Lu, Dongdong Zhang, Guofu Li, Yuwen Wang, Chunyang Men, Wenzhong Du, Xiangjian Zheng, Changbin Shi
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105642- (2022)
Summary: Cerebral cavernous malformation (CCM) is caused by loss-of-function mutations in CCM1, CCM2, or CCM3 genes of endothelial cells. It is characterized by pericyte deficiency. However, the role of pericytes in CCMs is not yet clarified. We foun
Externí odkaz:
https://doaj.org/article/560453f44d114a23ace36ac49856843b
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 59, Iss 6, Pp 828-834 (2020)
Objective: We aimed to evaluate the therapeutic effects of paclitaxel in combination with mTOR inhibitor everolimus on adriamycin-resistant breast cancer cell line MDA-MB-231 (MDA-MB-231/ADR). Materials and methods: MDA-MB-231/ADR cells were treated
Externí odkaz:
https://doaj.org/article/678499fd9ba74ec5bf81d4a76acf67ae
Autor:
Janne Koskimäki, Dongdong Zhang, Yan Li, Laleh Saadat, Thomas Moore, Rhonda Lightle, Sean P. Polster, Julián Carrión-Penagos, Seán B. Lyne, Hussein A. Zeineddine, Changbin Shi, Robert Shenkar, Sharbel Romanos, Kenneth Avner, Abhinav Srinath, Le Shen, Matthew R. Detter, Daniel Snellings, Ying Cao, Miguel A. Lopez-Ramirez, Gregory Fonseca, Alan T. Tang, Pieter Faber, Jorge Andrade, Mark Ginsberg, Mark L. Kahn, Douglas A. Marchuk, Romuald Girard, Issam A. Awad
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Cerebral cavernous malformations (CCMs) are dilated capillaries causing epilepsy and stroke. Inheritance of a heterozygous mutation in CCM3/PDCD10 is responsible for the most aggressive familial form of the disease. Here we studied the diffe
Externí odkaz:
https://doaj.org/article/d491481086084d3caa544cf265ff3ba4
Autor:
Shiguang Zhao, Jianing Wu, Chunlei Wang, Huailei Liu, Xingli Dong, Chen Shi, Changbin Shi, Yaohua Liu, Lei Teng, Dayong Han, Xiaofeng Chen, Guang Yang, Ligang Wang, Chen Shen, Huadong Li
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63682 (2013)
BACKGROUND: We performed a systematic review and meta-analysis to address the (added) value of intraoperative 5-aminolevulinic acid (5-ALA)-guided resection of high-grade malignant gliomas compared with conventional neuronavigation-guided resection,
Externí odkaz:
https://doaj.org/article/db829d0e8c5f4d9daf6c18c59b2026d3
Autor:
Xi Yang, Zifeng Dai, Caixia Gao, Yongqiang Yin, Changbin Shi, Renjing Liu, Qichuan Zhuge, Yue Huang, Bin Zhou, Zhiming Han, Xiangjian Zheng
Publikováno v:
J Cereb Blood Flow Metab
Cerebral cavernous malformation (CCM) is a brain vascular disease which can cause stroke, cerebral hemorrhage and neurological deficits in affected individuals. Loss-of-function mutations in three genes ( CCM1, CCM2 and CCM3) cause CCM disease. Multi
Autor:
Ying Li, Romuald Girard, Abhinav Srinath, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel Romanos, Thom Moore, Dorothy Debiasse, Mira Antonopoulos, Akash Bindal, Heba Ali, Agnieszka Stadnik, Justine Lee, Miguel A Lopez-Ramirez, Changbin Shi, Issam A Awad
Publikováno v:
Stroke. 54
Introduction: Cavernous Angiomas (CAs) are vascular malformations characterized by clusters of blood-filled capillary spaces lined by “leaky” endothelium. While mutations in endothelial cells have long been recognized as necessary for lesion gene